Hellem Cristina Silva Carneiro
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View article: The Dynamics of Cryptococcus neoformans Cell and Transcriptional Remodeling during Infection
The Dynamics of Cryptococcus neoformans Cell and Transcriptional Remodeling during Infection Open
The phenotypic plasticity of Cryptococcus neoformans is widely studied and demonstrated in vitro, but its influence on pathogenicity remains unclear. In this study, we investigated the dynamics of cryptococcal cell and transcriptional remo…
View article: Environmental Triazole Induces Cross-Resistance to Clinical Drugs and Affects Morphophysiology and Virulence of Cryptococcus gattii and C. neoformans
Environmental Triazole Induces Cross-Resistance to Clinical Drugs and Affects Morphophysiology and Virulence of Cryptococcus gattii and C. neoformans Open
Cryptococcus gattii and Cryptococcus neoformans are environmental fungi that cause cryptococcosis, which is usually treated with amphotericin B and fluconazole. However, therapeutic failure is increasing because of the emergence of resista…
View article: Influenza A Virus as a Predisposing Factor for Cryptococcosis
Influenza A Virus as a Predisposing Factor for Cryptococcosis Open
Influenza A virus (IAV) infects millions of people annually and predisposes to secondary bacterial infections. Inhalation of fungi within the Cryptococcus complex causes pulmonary disease with secondary meningo-encephalitis. Underlying pul…
View article: A subdose of fluconazole alters the virulence of<i>Cryptococcus gattii</i>during murine cryptococcosis and modulates type I interferon expression
A subdose of fluconazole alters the virulence of<i>Cryptococcus gattii</i>during murine cryptococcosis and modulates type I interferon expression Open
Cryptococcosis is an invasive infection caused by yeast-like fungus of the genera Cryptococcus spp. The antifungal therapy for this disease provides some toxicity and the incidence of infections caused by resistant strains increased. Thus,…