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View article: WCN24-360 The use of convalescent plasma in a kidney transplant recipient COVID-19 patient: A case report from the perspective of viral load evolution and immune response
WCN24-360 The use of convalescent plasma in a kidney transplant recipient COVID-19 patient: A case report from the perspective of viral load evolution and immune response Open
By mid-2020, most of the world was grappling with the millions of deaths caused by the COVID-19 pandemic. In this context, Uruguay was an outlier, managing the situation with remarkable success 1. By this time, convalescent plasma (CP) the…
View article: What have we learned from a case of convalescent plasma treatment in a two-time kidney transplant recipient COVID-19 patient? A case report from the perspective of viral load evolution and immune response
What have we learned from a case of convalescent plasma treatment in a two-time kidney transplant recipient COVID-19 patient? A case report from the perspective of viral load evolution and immune response Open
Coronavirus disease 2019 (COVID-19), an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, can have a wide range of clinical manifestations, ranging from asymptomatic disease to potentially…
View article: Antioxidant Capacity and NF-kB-Mediated Anti-Inflammatory Activity of Six Red Uruguayan Grape Pomaces
Antioxidant Capacity and NF-kB-Mediated Anti-Inflammatory Activity of Six Red Uruguayan Grape Pomaces Open
Grape pomaces have a wide and diverse antioxidant phenolics composition. Six Uruguayan red grape pomaces were evaluated in their phenolics composition, antioxidant capacity, and anti-inflammatory properties. Not only radical scavenging met…
View article: Murine colon organoids as a novel model to study Trypanosoma cruzi infection and interactions with the intestinal epithelium
Murine colon organoids as a novel model to study Trypanosoma cruzi infection and interactions with the intestinal epithelium Open
Chagas disease (CD) is a life-threatening illness caused by the parasite Trypanosoma cruzi ( T. cruzi ). With around seven million people infected worldwide and over 50,000 deaths per year, CD is a major public health issue in Latin Americ…
View article: Jejunum-derived NF-κB reporter organoids as 3D models for the study of TNF-alpha-induced inflammation
Jejunum-derived NF-κB reporter organoids as 3D models for the study of TNF-alpha-induced inflammation Open
Inflammation is an important process for epithelial barrier protection but when uncontrolled, it can also lead to tissue damage. The nuclear factor-kappa light chain enhancer of activated B cells (NF-κB) signaling pathway is particularly r…
View article: ¿What did we learn from Convalescent plasma treatment in a COVID-19 patient two-time kidney transplanted? A case report from the viral and immune response evolution perspective
¿What did we learn from Convalescent plasma treatment in a COVID-19 patient two-time kidney transplanted? A case report from the viral and immune response evolution perspective Open
Background: COVID-19, an infectious disease caused by SARS-CoV-2 virus, can provoke a vast range of clinical manifestations, ranging from asymptomatic to potentially life-threatening complications. At the beginning, convalescent plasma the…
View article: Ivermectin reduces in vivo coronavirus infection in a mouse experimental model
Ivermectin reduces in vivo coronavirus infection in a mouse experimental model Open
View article: The Anticancer Peptide CIGB-552 Exerts Anti-Inflammatory and Anti-Angiogenic Effects through COMMD1
The Anticancer Peptide CIGB-552 Exerts Anti-Inflammatory and Anti-Angiogenic Effects through COMMD1 Open
CIGB-552 is a synthetic anti-tumor peptide capable of reducing tumor size and increasing the lifespan of tumor-bearing mice. Part of its anti-cancer effects consists of inducing apoptosis, modulating NF-kB signaling pathway, and the angiog…
View article: Ivermectin reduces coronavirus infection<i>in vivo</i>: a mouse experimental model
Ivermectin reduces coronavirus infection<i>in vivo</i>: a mouse experimental model Open
SARS-CoV2 is a single strand RNA virus member of the type 2 coronavirus family, responsible for causing COVID-19 disease in humans. The objective of this study was to test the ivermectin drug in a murine model of coronavirus infection usin…