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View article: Hypovitaminosis D Does Not Aggravate the Progression of Gentamicin-Induced Kidney Injury in Rats
Hypovitaminosis D Does Not Aggravate the Progression of Gentamicin-Induced Kidney Injury in Rats Open
Background/Objectives: Gentamicin is one of the most effective and widely used antibiotics to treat serious infections. In addition to its bactericidal properties, gentamicin has a nephrotoxic effect that results in acute kidney injury (AK…
View article: Paricalcitol Improves the Angiopoietin/Tie-2 and VEGF/VEGFR2 Signaling Pathways in Adriamycin-Induced Nephropathy
Paricalcitol Improves the Angiopoietin/Tie-2 and VEGF/VEGFR2 Signaling Pathways in Adriamycin-Induced Nephropathy Open
Renal endothelial cell (EC) injury and microvascular dysfunction contribute to chronic kidney disease (CKD). In recent years, increasing evidence has suggested that EC undergoes an endothelial-to-mesenchymal transition (EndoMT), which migh…
View article: Editorial: Contributing Factors to Renal Dysfunction: Fetal Programming, Hormones, and Epigenetic
Editorial: Contributing Factors to Renal Dysfunction: Fetal Programming, Hormones, and Epigenetic Open
EDITORIAL article Front. Physiol., 06 December 2021Sec. Renal Physiology and Pathophysiology https://doi.org/10.3389/fphys.2021.793730
View article: Effect of Calcitriol on the Renal Microvasculature Differentiation Disturbances Induced by AT1 Blockade During Nephrogenesis in Rats
Effect of Calcitriol on the Renal Microvasculature Differentiation Disturbances Induced by AT1 Blockade During Nephrogenesis in Rats Open
Alterations in the renal vasculature during fetal programming can cause disturbances in renal structure and function that persist into adulthood. Calcitriol can affect cellular differentiation and proliferation, and promote endothelial cel…
View article: Protective effect of calcitriol on rhabdomyolysis-induced acute kidney injury in rats
Protective effect of calcitriol on rhabdomyolysis-induced acute kidney injury in rats Open
Glycerol injection in rats can lead to rhabdomyolysis, with the release of the intracellular muscle content to the extracellular compartment and acute kidney injury (AKI). Oxidative stress and the inflammatory processes contribute to the d…
View article: Renal developmental disturbances and their long-term consequences in female pups from vitamin D-deficient mothers: involved mechanisms
Renal developmental disturbances and their long-term consequences in female pups from vitamin D-deficient mothers: involved mechanisms Open
The mechanisms involved in kidney disturbances during development, induced by vitamin D 3 deficiency in female rats, that persist into adulthood were evaluated in this study. Female offspring from mothers fed normal (control group, n =8) o…
View article: Calcitriol reduces kidney development disorders in rats provoked by losartan administration during lactation
Calcitriol reduces kidney development disorders in rats provoked by losartan administration during lactation Open
View article: Cryogenic role of central endogenous hydrogen sulfide in the rat model of endotoxic shock
Cryogenic role of central endogenous hydrogen sulfide in the rat model of endotoxic shock Open
View article: Involvement of endogenous central hydrogen sulfide (H<sub>2</sub>S) in hypoxia-induced hypothermia in spontaneously hypertensive rats
Involvement of endogenous central hydrogen sulfide (H<sub>2</sub>S) in hypoxia-induced hypothermia in spontaneously hypertensive rats Open
Spontaneously hypertensive rats (SHR) display autonomic imbalance and abnormal body temperature (Tb) adjustments. Hydrogen sulfide (H 2 S) modulates hypoxia-induced hypothermia, but its role in SHR thermoregulation is unknown. We tested th…