Héloïse Rach
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A study on electroretinography as a biomarker for seasonal vulnerability in depression Open
Depressive disorders involve disruptions in light signal processing. Seasonal Affective Disorder (SAD) has been linked to abnormalities in phototransduction, including impaired retinal responses and sleep disturbances. Similar retinal anom…
Pupillary response to blue light as a biomarker of seasonal pattern in Major Depressive Episode: A clinical study using pupillometry Open
Depressive disorders are characterized by disturbances in light signal processing. More specifically, an alteration of the melanopsin response is suggested. The post-illumination pupillary response (PIPR) to blue light (post-blue PIPR) is …
The electroretinography to identify biomarkers of idiopathic hypersomnia and narcolepsy type 1 Open
Summary Hypersomnia spectrum disorders are underdiagnosed and poorly treated due to their heterogeneity and absence of biomarkers. The electroretinography has been proposed as a proxy of central dysfunction and has proved to be valuable to…
Pupillometry to differentiate idiopathic hypersomnia from narcolepsy type 1 Open
Summary Idiopathic hypersomnia is poorly diagnosed in the absence of biomarkers to distinguish it from other central hypersomnia subtypes. Given that light plays a main role in the regulation of sleep and wake, we explored the retinal mela…