Explanipedia

T Lymphoblastic Leukemia Presenting as Bilateral Renal Masses: A Case Report Open

Chhavi Goyal, Ajay Yadav, Hemant Malhotra, Julia Vasant, Abhilash Reddy , et al. · 2025

Gossypiboma: diagnostic impasse - a case report Open

Ashish Kumar, Gunjan Malhotra, Hemant Malhotra, Raman Malhotra · 2025

Gossypiboma/textiloma is a retained foreign body reaction to a surgical gauze or towel unintentionally retained inside the body following surgery, which is often missed to be diagnosed. The foreign body reaction to the retained gauze piece…

Juvenile Hereditary Hemochromatosis: A Case Report Open

Chhavi Goyal, Omkar Kalidasrao Choudhari, Disha SATYA, Priyanka Soni, Naveen Gupta , et al. · 2025

Introduction: Hereditary hemochromatosis is an inherited condition where an excess of iron is absorbed from the diet, causing its accumulation in vital organs and subsequent organ damage. Very few cases of hereditary hemochromatosis have b…

Retrospective Analysis of Patients with Multiple Myeloma Post Autologous Stem Cell Transplant Open

Disha SATYA, Priyanka CHOUDHARY, Chhavi Goyal, Omkar Kalidasrao Choudhari, Priyanka Soni , et al. · 2025

Introduction: Multiple myeloma is a plasma cell disorder characterised by hypercalcaemia, renal dysfunction, and anaemia with bony lytic lesions. While multiple myeloma remains incurable, advancements in treatment have significantly improv…

Clinical and Molecular Profiles and Treatment Outcomes in Patients With Acute Promyelocytic Leukaemia: A Single-Centre Experience Open

Omkar Kalidasrao Choudhari, Priyanka Soni, Lalit Mohan Sharma, Disha SATYA, Satyajeet Soni , et al. · 2025

Most patients with APL presented with fever and bleeding. The bcr1 transcript of PML-RARα was the most commonly observed. ATRA and ATO-based treatment was associated with high remission rates, manageable toxicity, and a low relapse rate.

2025 European LeukemiaNet recommendations for the management of chronic myeloid leukemia Open

Jane F. Apperley, Dragana Milojković, Nicholas C.P. Cross, Henrik Hjorth‐Hansen, Andreas Hochhaus , et al. · 2025

In this 5th version of the European LeukemiaNet guidance for adult patients, there are important changes in several areas of management based on evidence available since 2020, including the World Health Organisation’s reclassification of C…

Management of chronic myeloid leukemia in 2025 Open

Hagop M. Kantarjian, Massimo Breccia, Fadi G. Haddad, Rüdiger Hehlmann, Ghayas C. Issa , et al. · 2025

Chronic myeloid leukemia (CML) has an annual incidence of approximately two cases per 100,000. The reduction in annual mortality from 10%–20% to 1% with BCR::ABL1 tyrosine kinase inhibitors (TKIs) has resulted in an increased prevalence in…

NAMS task force report on breast cancer in India Open

Sudeep Gupta, Atul Batra, Shankar Prinja, Hemant Malhotra, T. Mohanapriya , et al. · 2025

Tacrolimus-Induced Diabetic Ketoacidosis (DKA) in Post Bone Marrow Transplant Patient Open

Omkar Kalidasrao Choudhari, Disha SATYA, Naveen Gupta, Priyanka Bhatia Soni, Purvish M. Parikh , et al. · 2025

Introduction. Hematopoietic stem cell transplant is an established management in various Blood disorders. This contemporary management has improved patient survival; tackling immunosuppression and managing post-transplant complications is …

Genetic Counselling, Testing, and Management of Hereditary Breast and Ovarian Cancer Syndrome in India: Updated Expert Consensus Recommendations from Indian Society of Medical and Pediatric Oncology Open

Hemant Malhotra, Raja Pramanik, S. Srinivas, Pradyna Kotwal, Nikita Mehra , et al. · 2025

Introduction Hereditary breast and ovarian cancer (HBOC) is driven by mutations in BRCA1/2 and related genes. Their understanding is vital to appropriate management of such patients and at-risk families, including counselling and genetic t…

Quality-of-care indicators for oncology management: an analysis of Asia-Pacific healthcare and oncology indicators Open

Ravindran Kanesvaran, Evelyn Wong, B. Keam, N. Prasongsook, Hemant Malhotra , et al. · 2025

Clinical Outcomes of Patients with Multiple Myeloma Presenting with Renal Failure Open

Julia Vasant, Naveen Gupta, Hemant Malhotra, Suraj Godara, Ajay Yadav , et al. · 2025

Aims and Objective This article studies the clinical outcome of patients with multiple myeloma who have renal failure at presentation. Methodology Patients with multiple myeloma presenting with serum creatinine of more than or equal to 2 m…

Efficacy and Safety of Biosimilar Cetuximab Versus Innovator Cetuximab in Indian Patients With Head and Neck Cancer: A Multicenter, Randomized, Double-Blind, Phase III Trial Open

Kumar Prabhash, Chetan Deshmukh, Hemant Malhotra, Atul Sharma, Minish Jain , et al. · 2024

PURPOSE Squamous cell carcinoma of the head and neck (SCCHN) is the sixth most common cancer, with approximately 225,419 new cases with over 125,000 deaths annually in India. This trial compared the efficacy and safety of biosimilar cetuxi…

Practical Consensus Guidelines on the Use of Cetuximab in Head and Neck Squamous Cell Carcinoma (HNSCC) Open

Purvish M. Parikh, Ghanashyam Biswas, N. Dhamne, Chetan Dilip Deshmukh, Sewanti Limaye , et al. · 2024

Head and neck squamous cell carcinoma (HNSCC) is the most common malignancy group in India and several other low- and middle-income countries. Currently, majority of the patients present in advanced stage where systemic therapy is standard…

Early Diagnosis of Gall Bladder Cancer: An Appeal Open

Vinay K. Kapoor, Ajay Sharma, Hemant Malhotra, Neha Sethi, Nikhil Bansal , et al. · 2024

A team of gastroenterologists, oncologists, pathologists, radiologists, and surgeons from a university teaching hospital in western India make an appeal, through the Journal, to the statutory bodies and the scientific societies related to …

Indian Society of Medical and Paediatric Oncology (ISMPO)—Breast Cancer in Young Guidelines Open

Jyoti Bajpai, Shruti Sanjay Gandhi, Senthil Rajappa, Rima Pathak, Shalaka Joshi , et al. · 2024

Breast cancer (BC) is the most common type of cancer globally and in India. In India, BC is more common among younger women compared with Western counterparts. Younger women with BC tend to have a less favorable outcome as they are more li…

ISMPO Guidelines for Diagnosis and Management of Early Breast Cancer Open

Randeep Singh, Aditya Sarin, Padmaj Kulkarni, Amit Verma, Arun Kumar Rathi , et al. · 2024

The management of breast cancer has become increasingly complex and multidisciplinary in the recent past. Further, there are unique constraints and opportunities for cancer care delivery in India, including socioeconomic, geographic, and o…

Bringing global hematology research to the forefront Open

Andrés Gómez‐De León, Andrés Noyola‐Perez, Lourdes Gil-Flores, Hemant Malhotra, Vasile Musteata , et al. · 2024

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Association of Positive Family History and Clinicopathological Features in Breast Cancer in Young Indian Females – A Pilot Study Open

Jaishree Goyal, Ajay Yadav, Hemant Malhotra · 2024

A BSTRACT Introduction: Breast cancer is the most common cancer in Indian females, accounting for 31.8% of all cancers. Young women with breast cancer are those under 40 years of age. These patients have higher chances of positive family h…

Oncofertility and Pregnancy in Adolescent and Young Adult Cancers: Physicians' Knowledge and Preferences in India Open

Sharada Mailankody, Jyoti Bajpai, Puneet Arora, Rinoy Sreedharan, Prakash Chitalkar , et al. · 2024

PURPOSE The treatment outcomes of adolescent and young adult (AYA) cancers have improved with advanced oncology care. Hence, fertility preservation (FP) and post-therapy pregnancies (PTPs) become vital issues. MATERIALS AND METHODS An onli…

FDG PET-CT in Clinical Management of a Rare Case of Primary Hepatic Lymphoma: Role and Challenges Open

Tarun Kumar Jain, Naveen Gupta, Hemant Malhotra, Lalit Mohan Sharma · 2023

The common differential diagnoses for multiple space-occupying hepatic lesions (SOL) are metastases, multifocal hepatocellular carcinoma, and abscess. Primary hepatic lymphomas are rare entities that present many challenges with regard to …

Genetic counseling for hereditary cancers: Not everybody’s cup of tea! Open

Rekha Gupta, Satyajeet Soni, Hemant Malhotra · 2023

We read with deep interest the review article published in the previous issue of Cancer Research Statistics and Treatment authored by Ulhaq et al.[1] We feel that this manuscript is of utmost importance for practicing oncologists and the j…

Outcome in patients with multiple myeloma: Does age matter? Open

Satyajeet Soni, Hemant Malhotra · 2023

Plasma cell dyscrasias are a mixed bag of plasma cell malignancies and include indolent monoclonal gammopathy of undetermined significance (MGUS) at one end of the spectrum and aggressive plasma cell leukemia at the other end. Multiple mye…

ChatGPT—Preliminary Overview with Implications for Medicine and Oncology Open

Purvish M. Parikh, Dinesh Shah, Urvish Parikh, Ajit Venniyoor, Govind Babu , et al. · 2023

This review provides an overview about the OpenAI system's natural language chat bot called ChatGPT. It focuses on the preliminary assessment of its unique features, advantages, limitations, role in manuscript writing, value in oncology, a…

Practical Clinical Consensus Guidelines for the Management of Cancer Associated Anemia in Low- and Middle-Income Countries Open

Purvish M. Parikh, Shyam Aggarwal, Ghanashyam Biswas, Seema Gulia, Vivek Agarwala , et al. · 2023

Cancer-associated anemia (CAA) remains a major unmet need that compromises overall survival (OS) and quality of life (QoL). Currently, available guidelines do not take into consideration the unique challenges in low- and middle-income coun…

Hypercalcemia in Chronic Myeloid Leukemia: An Unusual Presentation Open

Khushboo Agarwal, Naveen Gupta, Hemant Malhotra · 2023

Hypercalcemia in CML is an unusual paraneoplastic syndrome and is associated with worse prognosis and reduced survival. It usually seen in blast crisis or accelerated phase but can also indicate bony infiltration by cancer cells. Multiple …

Editorial Open

Purvish Parikh, Hemant Malhotra, Lalit Mohan Sharma, Ajay Singh Yadav, Naveen Gupta · 2022

International Journal of Molecular and Immuno Oncology (IJMIO) is a peer-reviewed journal where clinicians and researchers can contribute and keep up with the fast-paced developments in Molecular Biology and Immuno oncology.

Patterns of Neck Nodal Metastasis from Oral Cavity Carcinoma Open

Nitin Khunteta, Ayush Makkar, Jaspreet Singh Badwal, Prakhar Katta, Dinesh Choudhary , et al. · 2022

Objectives The aim is to study the patterns of lymph node metastasis from various sites in oral cavity cancer and determine the risk factors for metastasis. Materials and Methods It is a prospective observational study. The inclusion crite…

Pembrolizumab weight based dosing – A call for policy change Open

Amol Patel, Amol Akhade, Purvish M. Parikh, Atul Sharma, Hemant Malhotra , et al. · 2022

Immuno-oncology (IO) drugs are now approved for use in metastatic, adjuvant, and/or neoadjuvant setting for a growing list of cancers including non-small cell lung cancer, small cell lung cancer, melanoma, urothelial cancer, renal cell car…

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