Hend Abd-Allah
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View article: Effect of Moringa oleifera and ivermectin nanoparticles on the immunopathological response during experimental trichinosis in mice
Effect of Moringa oleifera and ivermectin nanoparticles on the immunopathological response during experimental trichinosis in mice Open
Trichinella spiralis ( T. spiralis ) infection dynamically modulates macrophage polarization. It promotes M1 macrophage polarization, enhancing the pro-inflammatory pathways. This study investigates how ivermectin nanoparticles (IVM-NP) an…
View article: Genetic Characterization and Pathogenesis of Highly Pathogenic Avian Influenza Virus A (H5N1) Isolated in Egypt During 2021–2023
Genetic Characterization and Pathogenesis of Highly Pathogenic Avian Influenza Virus A (H5N1) Isolated in Egypt During 2021–2023 Open
Highly pathogenic avian influenza (HPAI) viruses have recently had a substantial impact on global poultry production and public health. In Egypt, clade 2.3.4.4b HPAI H5N1 viruses were first isolated from wild birds in 2021 and then became …
View article: Evaluating the In Vitro Anthelmintic Activity of Zinc Oxide Nanoparticles (ZnO‐NPs) Against the Adult Stages of <i>Fasciola hepatica</i>
Evaluating the In Vitro Anthelmintic Activity of Zinc Oxide Nanoparticles (ZnO‐NPs) Against the Adult Stages of <i>Fasciola hepatica</i> Open
Background Fascioliasis represents one of the most significant parasitic and foodborne zoonotic diseases in the world. Resistance to currently deployed human and veterinary flukicides is a growing health problem. Zinc oxide nanoparticles (…
View article: Genetic and pathogenic potential of highly pathogenic avian influenza H5N8 viruses from live bird markets in Egypt in avian and mammalian models
Genetic and pathogenic potential of highly pathogenic avian influenza H5N8 viruses from live bird markets in Egypt in avian and mammalian models Open
Since its first isolation from migratory birds in Egypt in 2016, highly pathogenic avian influenza (HPAI) H5N8 has caused several outbreaks among domestic poultry in various areas of the country affecting poultry health and production syst…
View article: Simplex Lattice Design and Machine Learning Methods for the Optimization of Novel Microemulsion Systems to Enhance p-Coumaric Acid Oral Bioavailability: In Vitro and In Vivo Studies
Simplex Lattice Design and Machine Learning Methods for the Optimization of Novel Microemulsion Systems to Enhance p-Coumaric Acid Oral Bioavailability: In Vitro and In Vivo Studies Open
Novel p-coumaric acid microemulsion systems were developed to circumvent its absorption and bioavailability challenges. Simplex-lattice mixture design and machine learning methods were employed for optimization. Two optimized formulations …
View article: Gastroprotective Chitosan Nanoparticles Loaded with Oleuropein: An In Vivo Proof of Concept
Gastroprotective Chitosan Nanoparticles Loaded with Oleuropein: An In Vivo Proof of Concept Open
Oleuropein is the main constituent of olive leaf extract, and it has shown antioxidant and gastroprotective properties against gastric ulcers. Chitosan nanoparticles are known for their mucoadhesive abilities, and consequently, they can in…
View article: Combined Systemic Intake of K-ATP Opener (Nicorandil) and Mesenchymal Stem Cells Preconditioned With Nicorandil Alleviates Pancreatic Insufficiency in a Model of Bilateral Renal Ischemia/Reperfusion Injury
Combined Systemic Intake of K-ATP Opener (Nicorandil) and Mesenchymal Stem Cells Preconditioned With Nicorandil Alleviates Pancreatic Insufficiency in a Model of Bilateral Renal Ischemia/Reperfusion Injury Open
We used nicorandil, a K-ATP channel opener, to study the role of these channels in the amelioration of renal ischemia/reperfusion (I/R)-induced pancreatic injury, and the possible involvement of PI3K/Akt/mTOR signaling pathway. Forty-two m…
View article: CHITOSAN BASED POLYELECTROLYTE COMPLEX NANOPARTICLES: PREPARATION AND CHARACTERIZATION
CHITOSAN BASED POLYELECTROLYTE COMPLEX NANOPARTICLES: PREPARATION AND CHARACTERIZATION Open
Recently, the use of biodegradable polymers for specialized applications such as controlled release of drug formulations gained considerable attention. Biodegradable nanoparticles have been widely utilized in drug delivery systems. In this…
View article: Biological and Pharmacological Characterization of Ascorbic Acid and Nicotinamide Chitosan Nanoparticles against Insulin-Resistance-Induced Cognitive Defects: A Comparative Study
Biological and Pharmacological Characterization of Ascorbic Acid and Nicotinamide Chitosan Nanoparticles against Insulin-Resistance-Induced Cognitive Defects: A Comparative Study Open
High consumption of industrialized food with high fat content is generally associated with insulin resistance, which in turn causes memory impairment and cognitive decline. Nicotinamide and ascorbic acid are among the promising neuroprotec…