Explanipedia

Can PIM3 predict mortality adequately for patients admitted to Pediatric Intensive Care Unit in a resource limited setting? A single-center study Open

Desy Rusmawatiningtyas, Renova Astriani Hutapea, Antonius Hocky Pudjiadi, Firdian Makrufardi, Hennie Knoester , et al. · 2025

Hospital to Home Transitions for Children With Medical Complexity: A Scoping Review of Healthcare Professionals’ Experiences Open

Heleen N. Haspels, Hennie Knoester, Faridi S. van Etten‐Jamaludin, Clara D. van Karnebeek, Mattijs W. Alsem · 2025

Background Hospital‐to‐home (H2H) transitions for children with medical complexity (CMC) are challenging and time‐intensive, often overwhelming parents due to insufficient care coordination, poor communication among healthcare professional…

Bridging hospital to home for children with medical complexity and their families: an observational prospective cohort study protocol to assess the effectiveness of an innovative transitional care unit in the Netherlands (BRIDGE study) Open

Heleen N. Haspels, Misja Mikkers, Hennie Knoester, Nicolaas J. G. Jansen, Inge M. L. Ahout , et al. · 2025

Introduction Children with Medical Complexities (CMC) often require 24/7 expert care, which frequently necessitates prolonged (re)admissions to a university medical centre (UMC), thereby impeding discharge to home. The transition from hosp…

Hospital to home transition of children with medical complexities in the Netherlands: current practice Open

Heleen N. Haspels, Hennie Knoester, N. J. G. Jansen, Inge M. L. Ahout, Clara D. van Karnebeek , et al. · 2025

Children with Medical Complexity (CMC) often require 24/7 expert care, which may impede discharge from hospital to home (H2H) resulting in prolonged admission. Limited research exists on pediatric patients with delayed discharges and the u…

A Dutch paediatric palliative care guideline: a systematic review and evidence-based recommendations for symptom treatment Open

Kim C. van Teunenbroek, Renée L. Mulder, Inge M. L. Ahout, Karen Bindels‐de Heus, Catharina M. Delsman-van Gelder , et al. · 2024

Palliative care for children: methodology for the development of a national clinical practice guideline Open

Kim C. van Teunenbroek, Leontien C.M. Kremer, Eduard Verhagen, Johannes Verheijden, Hester Rippen , et al. · 2023

Background Provision of paediatric palliative care for children with life-threatening or life-limiting conditions and their families is often complex. Guidelines can support professionals to deliver high quality care. Stakeholders expresse…

Predicting long-term neurocognitive outcome after pediatric intensive care unit admission for bronchiolitis—preliminary exploration of the potential of machine learning Open

Eleonore S. V. de Sonnaville, Jacob Vermeule, Kjeld Oostra, Hennie Knoester, Job B. M. van Woensel , et al. · 2023

Purpose For successful prevention and intervention, it is important to unravel the complex constellation of factors that affect neurocognitive functioning after pediatric intensive care unit (PICU) admission. This study aims (1) to elucida…

Long-Term Follow-Up of Daily Life Functioning After Pediatric Intensive Care Unit Admission Open

Eleonore S. V. de Sonnaville, Marsh Königs, Cornelieke S.H. Aarnoudse-Moens, Job B. M. van Woensel, Jaap Oosterlaan , et al. · 2023

Children admitted to the PICU are at risk for long-term adverse daily life outcomes in terms of academic performance and school-related QoL. Findings suggest that lower intelligence may contribute to academic difficulties after PICU admiss…

Predicting Long-term Neurocognitive Outcome after Pediatric Intensive Care Unit Admission - Exploring the Potential of Machine Learning Open

Eleonore S. V. de Sonnaville, Jacob Vermeule, Kjeld Oostra, Hennie Knoester, Job B. M. van Woensel , et al. · 2023

Purpose: For successful prevention and intervention, it is important to unravel the complex constellation of factors that affect neurocognitive functioning after Pediatric Intensive Care Unit (PICU) admission. This study aims (1) to elucid…

Structured Multidisciplinary Follow-Up After Pediatric Intensive Care: A Model for Continuous Data-Driven Health Care Innovation Open

Eleonore S. V. de Sonnaville, Job B. M. van Woensel, Johannes B. van Goudoever, M.H. Otten, Lorynn Teela , et al. · 2023

OBJECTIVES: Morbidity after PICU admission for critical illness is a growing concern. Sequelae may occur in various domains of functioning and can only appropriately be determined through structured follow-up. Here, we describe the process…

Factors Associated With Delirium in Children: A Systematic Review and Meta-Analysis* Open

Erwin Ista, Chani Traube, Marjorie de Neef, Jan N. M. Schieveld, Hennie Knoester , et al. · 2023

OBJECTIVES: Pediatric delirium (PD) is a neuropsychiatric syndrome caused by a complex interplay between predisposing factors (e.g., age, cognitive impairment), acute illness, and environmental triggers. PD is associated with substantial m…

Neurocognitive, Psychosocial, and Quality of Life Outcomes After Multisystem Inflammatory Syndrome in Children Admitted to the PICU* Open

M.H. Otten, Corinne Buysse, Emmeline P. Buddingh, Suzanne W. J. Terheggen-Lagro, Erik G. J. von Asmuth , et al. · 2023

OBJECTIVES: To investigate neurocognitive, psychosocial, and quality of life (QoL) outcomes in children with Multisystem Inflammatory Syndrome in Children (MIS-C) seen 3–6 months after PICU admission. DESIGN: National prospective cohort st…

A Core Outcome Measurement Set for Pediatric Critical Care* Open

Neethi Pinto, Aline B. Maddux, Leslie A. Dervan, Alan G. Woodruff, Jessica Jarvis , et al. · 2022

Objectives: To identify a PICU Core Outcome Measurement Set (PICU COMS), a set of measures that can be used to evaluate the PICU Core Outcome Set (PICU COS) domains in PICU patients and their families. Design: A modified Delphi consensus p…

Long-Term Pulmonary Outcomes in Children Mechanically Ventilated for Severe Bronchiolitis* Open

Eleonore S. V. de Sonnaville, Hennie Knoester, Suzanne W. J. Terheggen‐Lagro, Marsh Königs, Jaap Oosterlaan , et al. · 2022

Objectives: Bronchiolitis is a common indication for mechanical ventilation in the PICU. Both bronchiolitis and invasive mechanical ventilation may cause adverse long-term pulmonary outcomes. This study investigates children with a history…

Long-term Neurocognitive Outcomes after Pediatric Intensive Care Unit Admission: Exploring the Role of Drug Exposure Open

Eleonore S. V. de Sonnaville, Jaap Oosterlaan, Sima A. Ghiassi, Ouke van Leijden, Hanneke van Ewijk , et al. · 2022

Introduction Concerns exist regarding the impact of widely-used clinical drugs on brain development. This study investigates long-term neurocognitive functioning in relation to frequently used drug exposure at the Pediatric Intensive Care …

Intelligence outcome of pediatric intensive care unit survivors: a systematic meta-analysis and meta-regression Open

Eleonore S. V. de Sonnaville, Marsh Königs, Ouke van Leijden, Hennie Knoester, Job B. M. van Woensel , et al. · 2022

Trends in Pediatric Palliative Care Research (TTPCR) 2021; Issue #12: Commentary on Vallianatos et al. Open

Arno Colenbrander, Hennie Knoester · 2022

This TPPCR commentary discusses the 2021 paper by Vallianatos et al, “Development of the Dutch Structure for Integrated Children's Palliative Care.” published in Children.

Intelligence Outcome of Pediatric Intensive Care Unit Survivors: A Systematic Meta-Analysis and Meta-Regression Open

Eleonore S. V. de Sonnaville, Marsh Königs, Ouke van Leijden, Hennie Knoester, Job B. M. van Woensel , et al. · 2021

Health Care Professionals' Experiences With Preloss Care in Pediatrics: Goals, Strategies, Obstacles, and Facilitators Open

Eline M. Kochen, Paul A. Boelen, Saskia Teunissen, Floor Jenken, Roos R. de Jonge , et al. · 2020

HCPs strive to improve parental coping after the child's death, yet apply strategies that positively influence parental preparedness and well-being during the end of life as well. Individual HCPs are left with many uncertainties. A more ro…

Hennie Knoester YOU? Author Swipe