Henriette Stoy
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View article: Nuclear actin polymerization rapidly mediates replication fork remodeling upon stress by limiting PrimPol activity
Nuclear actin polymerization rapidly mediates replication fork remodeling upon stress by limiting PrimPol activity Open
Cells rapidly respond to replication stress actively slowing fork progression and inducing fork reversal. How replication fork plasticity is achieved in the context of nuclear organization is currently unknown. Using nuclear actin probes i…
View article: Excessive reactive oxygen species induce transcription-dependent replication stress
Excessive reactive oxygen species induce transcription-dependent replication stress Open
View article: Replication fork plasticity upon replication stress requires rapid nuclear actin polymerization
Replication fork plasticity upon replication stress requires rapid nuclear actin polymerization Open
Cells rapidly respond to replication stress actively slowing fork progression and inducing fork reversal. How replication fork plasticity is achieved in the context of nuclear organization is currently unknown. Using nuclear actin probes i…
View article: Direct visualization of transcription-replication conflicts reveals post-replicative DNA:RNA hybrids
Direct visualization of transcription-replication conflicts reveals post-replicative DNA:RNA hybrids Open
View article: Short Arrestin-3-Derived Peptides Activate JNK3 in Cells
Short Arrestin-3-Derived Peptides Activate JNK3 in Cells Open
Arrestins were first discovered as suppressors of G protein-mediated signaling by G protein-coupled receptors. It was later demonstrated that arrestins also initiate several signaling branches, including mitogen-activated protein kinase ca…
View article: Locus-Specific Analysis of Replication Dynamics and Detection of DNA–RNA Hybrids by Immuno Electron Microscopy
Locus-Specific Analysis of Replication Dynamics and Detection of DNA–RNA Hybrids by Immuno Electron Microscopy Open
View article: Identification of a novel compound that simultaneously impairs the ubiquitin-proteasome system and autophagy
Identification of a novel compound that simultaneously impairs the ubiquitin-proteasome system and autophagy Open
The ubiquitin-proteasome system (UPS) and macroautophagy/autophagy are the main proteolytic systems in eukaryotic cells for preserving protein homeostasis, i.e., proteostasis. By facilitating the timely destruction of aberrant proteins, th…
View article: Poly(ADP-ribosyl)ation temporally confines SUMO-dependent ataxin-3 recruitment to control DNA double-strand break repair
Poly(ADP-ribosyl)ation temporally confines SUMO-dependent ataxin-3 recruitment to control DNA double-strand break repair Open
DNA damage-induced SUMOylation serves as a signal for two antagonizing proteins that both stimulate repair of DNA double-strand breaks (DSBs). Here, we demonstrate that the SUMO-dependent recruitment of the deubiquitylating enzyme ataxin-3…
View article: Cyclin A2 localises in the cytoplasm at the S/G2 transition to activate PLK1
Cyclin A2 localises in the cytoplasm at the S/G2 transition to activate PLK1 Open
Cyclin A2 is a key regulator of the cell cycle, implicated both in DNA replication and mitotic entry. Cyclin A2 participates in feedback loops that activate mitotic kinases in G2 phase, but why active Cyclin A2-CDK2 during the S phase does…
View article: HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis
HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis Open
View article: Histone Ubiquitination by the DNA Damage Response Is Required for Efficient DNA Replication in Unperturbed S Phase
Histone Ubiquitination by the DNA Damage Response Is Required for Efficient DNA Replication in Unperturbed S Phase Open
View article: Cyclin A2 localises in the cytoplasm at the S/G2 transition to activate PLK1
Cyclin A2 localises in the cytoplasm at the S/G2 transition to activate PLK1 Open
Cyclin A2 is a key regulator of the cell cycle, implicated both in DNA replication and mitotic entry. Cyclin A2 participates in feedback loops that activate mitotic kinases in G2-phase, but why active Cyclin A2-CDK2 during S phase does not…
View article: DNA damage during S-phase mediates the proliferation-quiescence decision in the subsequent G1 via p21 expression
DNA damage during S-phase mediates the proliferation-quiescence decision in the subsequent G1 via p21 expression Open
View article: Wall teichoic acids mediate increased virulence in Staphylococcus aureus
Wall teichoic acids mediate increased virulence in Staphylococcus aureus Open
View article: Peptide mini-scaffold facilitates JNK3 activation in cells
Peptide mini-scaffold facilitates JNK3 activation in cells Open
View article: How genetic errors in GPCRs affect their function: Possible therapeutic strategies
How genetic errors in GPCRs affect their function: Possible therapeutic strategies Open