Henrik Fox
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View article: Nocturnal Hypoxemic Burden Predicts Mortality in Patients Awaiting Heart Transplantation
Nocturnal Hypoxemic Burden Predicts Mortality in Patients Awaiting Heart Transplantation Open
Risk stratification for patients with end‐stage heart failure (HF) awaiting heart transplantation (HTX) is crucial. Sleep‐disordered breathing (SDB) is a prevalent comorbidity, yet the impact of its resultant hypoxemic burden remains uncle…
View article: Reducing sudden cardiac death by involving sleep disordered breathing in the big picture: why this novel approach deserves recognition
Reducing sudden cardiac death by involving sleep disordered breathing in the big picture: why this novel approach deserves recognition Open
Reducing sudden cardiac death by involving sleep disordered breathing @fox_henrik https://bit.ly/4n3Xszy.
View article: Comparative analysis of cardiac function before LVAD implantation in patients with and without early, acute right heart failure: insights from cardiac magnetic resonance
Comparative analysis of cardiac function before LVAD implantation in patients with and without early, acute right heart failure: insights from cardiac magnetic resonance Open
Background Early acute right heart failure (eaRHF) during left ventricular assist device (LVAD) implantation significantly impacts patient survival and complicates perioperative management. Although numerous clinical, echocardiographic, an…
View article: Safety and 1‐Year Outcomes After Transplanting Hearts From SARS‐CoV‐2 Positive Donors: Insights From an International Analysis
Safety and 1‐Year Outcomes After Transplanting Hearts From SARS‐CoV‐2 Positive Donors: Insights From an International Analysis Open
Background Uncertainties persist regarding the utilization of hearts from SARS‐CoV‐2‐positive donors for heart transplant (HT). This international study analyzed such HTs within the United States (US) and Germany, focusing on 1‐year outcom…
View article: Three-Year Outcomes of Catheter Ablation in Patients With End-Stage Heart Failure and Atrial Fibrillation
Three-Year Outcomes of Catheter Ablation in Patients With End-Stage Heart Failure and Atrial Fibrillation Open
View article: Sex and Treatment Outcomes of Atrial Fibrillation Ablation in End-Stage Heart Failure
Sex and Treatment Outcomes of Atrial Fibrillation Ablation in End-Stage Heart Failure Open
View article: A novel approach to treat atrial tachycardia by catheter ablation in patients after orthotopic biatrial heart transplantation: The L-line
A novel approach to treat atrial tachycardia by catheter ablation in patients after orthotopic biatrial heart transplantation: The L-line Open
View article: Effect of adaptive servo-ventilation on circulating biomarkers in patients with sleep apnoea after myocardial infarction: results of an ancillary analysis of the randomised TEAM-ASV I trial
Effect of adaptive servo-ventilation on circulating biomarkers in patients with sleep apnoea after myocardial infarction: results of an ancillary analysis of the randomised TEAM-ASV I trial Open
NCT02093377.
View article: Effects of atrial fibrillation ablation on arrhythmia burden and ventricular function in end‐stage heart failure: Lessons from CASTLE‐HTx
Effects of atrial fibrillation ablation on arrhythmia burden and ventricular function in end‐stage heart failure: Lessons from CASTLE‐HTx Open
Aims The CASTLE‐HTx trial showed the benefit of atrial fibrillation (AF) ablation compared to medical therapy in decreasing mortality, need for left ventricular assist device implantation or heart transplantation (HTx) in patients with end…
View article: Different ECLS Pump Configurations for Temporary Right Ventricular Assist Device in LVAD Patients: A Retrospective Case–Control Study
Different ECLS Pump Configurations for Temporary Right Ventricular Assist Device in LVAD Patients: A Retrospective Case–Control Study Open
Background: Acute right ventricular failure is a critical complication after left ventricular assist device (LVAD) implantation, often managed with a temporary paracorporeal right ventricular assist device (RVAD). This study examined three…
View article: Propensity score-based comparison of high-risk coronary artery bypass grafting vs. left ventricular assist device implantation in patients with coronary artery disease and advanced heart failure
Propensity score-based comparison of high-risk coronary artery bypass grafting vs. left ventricular assist device implantation in patients with coronary artery disease and advanced heart failure Open
Objectives Revascularization in patients with severely reduced left ventricular function and coronary artery disease (CAD) is associated with a high perioperative risk. In this setting, implantation of a durable left ventricular assist dev…
View article: Treating central sleep apnoea in heart failure: is positive airway pressure and adaptive servo-ventilation in particular the gold standard?
Treating central sleep apnoea in heart failure: is positive airway pressure and adaptive servo-ventilation in particular the gold standard? Open
This correspondence aims to discuss an alternative treatment algorithm for Cheyne–Stokes respiration in heart failure with reduced ejection fraction https://bit.ly/4dAfQdP
View article: Outcomes after <scp>SynCardia</scp>® temporary total artificial heart implantation: A 20‐year single‐center experience in 196 patients
Outcomes after <span>SynCardia</span>® temporary total artificial heart implantation: A 20‐year single‐center experience in 196 patients Open
Background The SynCardia® temporary total artificial heart (TAH) serves as a mechanical circulatory support device for patients suffering from irreversible biventricular failure. Methods This retrospective study analyzed 196 consecutive pa…
View article: Prognosis of patients in end-stage heart failure with atrial fibrillation treated with ablation: Insights from CASTLE-HTx
Prognosis of patients in end-stage heart failure with atrial fibrillation treated with ablation: Insights from CASTLE-HTx Open
View article: Sleep apnea in patients undergoing coronary artery bypass grafting: Impact on perioperative outcomes
Sleep apnea in patients undergoing coronary artery bypass grafting: Impact on perioperative outcomes Open
Summary Sleep‐disordered breathing is common in patients with coronary artery disease undergoing coronary artery bypass grafting. Sleep‐disordered breathing is associated with increased perioperative morbidity, arrhythmias (e.g. atrial fib…
View article: Pulmonary Vascular Resistance to Predict Right Heart Failure in Patients Undergoing Left Ventricular Assist Device Implantation
Pulmonary Vascular Resistance to Predict Right Heart Failure in Patients Undergoing Left Ventricular Assist Device Implantation Open
Right heart failure (RHF) is associated with poor outcomes, especially in patients undergoing left ventricular assist device (LVAD) implantation. The aim of this study was to identify predictors of RHF after LVAD implantation. Of 129 conse…
View article: Inflammation and Fibrosis in Sleep-Disordered Breathing after Acute Myocardial Infarction
Inflammation and Fibrosis in Sleep-Disordered Breathing after Acute Myocardial Infarction Open
Background: After acute myocardial infarction (AMI), inflammatory processes promote tissue remodeling at the infarct site. Procollagen III amino-terminal propeptide (PIIINP) is a circulating biomarker of type III collagen synthesis that ha…
View article: Echocardiographic mechanical dyssynchrony predicts long-term mortality in patients with cardiac resynchronisation therapy
Echocardiographic mechanical dyssynchrony predicts long-term mortality in patients with cardiac resynchronisation therapy Open
View article: A case report: transfemoral transcatheter aortic valve replacement with a dedicated valve system for severe aortic regurgitation in a patient with a left ventricular assist device
A case report: transfemoral transcatheter aortic valve replacement with a dedicated valve system for severe aortic regurgitation in a patient with a left ventricular assist device Open
Background Up to 30% of patients with the left ventricular assist device (LVAD) develop moderate to severe aortic regurgitation (AR) within the first year. Surgical aortic valve replacement (SAVR) is the treatment of choice in patients wit…
View article: Value of implant-based telemonitoring in the high-risk population of ventricular assist device patients
Value of implant-based telemonitoring in the high-risk population of ventricular assist device patients Open
Funding Acknowledgements Type of funding sources: None. Background Telemonitoring of heart failure (HF) patients is an evolving field. Prior studies presented promising results. However, the relevance of telemonitoring in the specific coho…
View article: Left Ventricular Unloading in Patients on Venoarterial Extracorporeal Membrane Oxygenation Therapy in Cardiogenic Shock: Prophylactic Versus Bail-Out Strategy
Left Ventricular Unloading in Patients on Venoarterial Extracorporeal Membrane Oxygenation Therapy in Cardiogenic Shock: Prophylactic Versus Bail-Out Strategy Open
Background: The benefit of prophylactic left ventricular (LV) unloading during venoarterial extracorporeal membrane oxygenation (VA-ECMO) in selected patients at risk of developing LV distension remains unclear. Methods: We enrolled 136 pa…
View article: Blood taken immediately after fatal resuscitation attempts yields higher quality DNA for genetic studies as compared to autopsy samples
Blood taken immediately after fatal resuscitation attempts yields higher quality DNA for genetic studies as compared to autopsy samples Open
Background The out-of-hospital cardiac arrest (OHCA) in the young may be associated with a genetic predisposition which is relevant even for genetic counseling of relatives. The identification of genetic variants depends on the availabilit…
View article: The Role of Daily Implant-Based Multiparametric Telemonitoring in Patients with a Ventricular Assist Device
The Role of Daily Implant-Based Multiparametric Telemonitoring in Patients with a Ventricular Assist Device Open
The telemonitoring of heart failure (HF) patients is becoming increasingly important. This study aimed to evaluate the benefit of telemonitoring in end-stage HF patients with a ventricular-assistance device (VAD). A total of 26 HF-patients…
View article: Long-term assist device patients admitted to ICU: Tips and pitfalls
Long-term assist device patients admitted to ICU: Tips and pitfalls Open
Left ventricular assist device (LVAD) therapy is well-established in the treatment of end-stage cardiac failure. Indications are bridge to transplant (BTT), bridge to candidacy (BTC), bridge to recovery (BTR), and destination therapy (DT).…
View article: Cognitive function in late‐stage HFpEF patients with tricuspid regurgitation undergoing transcatheter tricuspid valve intervention
Cognitive function in late‐stage HFpEF patients with tricuspid regurgitation undergoing transcatheter tricuspid valve intervention Open
Objectives This study evaluates the impact of transcatheter tricuspid valve interventions (TTVI) on cognitive function (CF), quality of life (QOL), and exercise capacity in late‐stage heart failure with preserved ejection fraction (HFpEF) …
View article: Noninvasive evaluation of the hemodynamic status in patients after heart transplantation or left ventricular assist device implantation
Noninvasive evaluation of the hemodynamic status in patients after heart transplantation or left ventricular assist device implantation Open
Introduction Hemodynamic assessment is crucial after heart transplantation (HTX) or left ventricular assist device (LVAD) implantation. Gold-standard is invasive assessment via thermodilution (TD). Noninvasive pulse contour analysis (NPCA)…
View article: Early identification of heart failure deterioration through respiratory monitoring with adaptive servo‐ventilation
Early identification of heart failure deterioration through respiratory monitoring with adaptive servo‐ventilation Open
Summary Cardiac decompensation is associated with worse prognosis in patients with heart failure. Reliable methods to predict cardiac decompensation events are not yet available. Sleep‐disordered breathing (SDB) is a frequent comorbidity i…
View article: Preoperative Nutritional Optimization and Physical Exercise for Patients Scheduled for Elective Implantation for a Left-Ventricular Assist Device—The PROPER-LVAD Study
Preoperative Nutritional Optimization and Physical Exercise for Patients Scheduled for Elective Implantation for a Left-Ventricular Assist Device—The PROPER-LVAD Study Open
Background: Prehabilitation is gaining increasing interest and shows promising effects on short- and long-term outcomes among patients undergoing major surgery. The effect of multimodal, interdisciplinary prehabilitation has not yet been s…
View article: Design of the remedē System Therapy (rēST) study: A prospective non-randomized post-market study collecting clinical data on safety and effectiveness of the remedē system for the treatment of central sleep apnea
Design of the remedē System Therapy (rēST) study: A prospective non-randomized post-market study collecting clinical data on safety and effectiveness of the remedē system for the treatment of central sleep apnea Open
This will be the largest prospective study evaluating long-term safety and effectiveness of transvenous phrenic nerve stimulation for the treatment of moderate to severe CSA in adult patients.
View article: Impact of Sleep-Disordered Breathing Treatment on Ventricular Tachycardia in Patients with Heart Failure
Impact of Sleep-Disordered Breathing Treatment on Ventricular Tachycardia in Patients with Heart Failure Open
Background: Sleep-disordered breathing (SDB) is a highly common comorbidity in patients with heart failure (HF), and a known risk factor for ventricular tachycardia (VT) development. However, little is known about the impact of SDB treatme…