Henry Ng
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View article: Circulating Markers of Neutrophil Extracellular Traps Are of Prognostic Value in Patients With COVID-19
Circulating Markers of Neutrophil Extracellular Traps Are of Prognostic Value in Patients With COVID-19 Open
OBJECTIVE: The full spectrum of coronavirus disease 2019 (COVID-19) infection ranges from asymptomatic to acute respiratory distress syndrome, characterized by hyperinflammation and thrombotic microangiopathy. The pathogenic mechanisms are…
View article: BDNF val66met genotype is not associated with psychological distress: A cross-sectional study in Indonesian Pharmacy young adults
BDNF val66met genotype is not associated with psychological distress: A cross-sectional study in Indonesian Pharmacy young adults Open
The number of mental disorders has been increasing but has yet to receive sufficient attention. In particular, healthcare students and professionals tend to have high stress burden. Finding the root cause of psychological distress is impor…
View article: Correlates of protection, viral load trajectories and symptoms in BA.1, BA.1.1 and BA.2 breakthrough infections in triple vaccinated healthcare workers
Correlates of protection, viral load trajectories and symptoms in BA.1, BA.1.1 and BA.2 breakthrough infections in triple vaccinated healthcare workers Open
Background Booster vaccine doses offer protection against severe COVID-19 caused by omicron but are less effective against infection. Characteristics such as serological correlates of protection, viral abundance, and clearance of omicron i…
View article: Long‐term SARS‐CoV‐2‐specific and cross‐reactive cellular immune responses correlate with humoral responses, disease severity, and symptomatology
Long‐term SARS‐CoV‐2‐specific and cross‐reactive cellular immune responses correlate with humoral responses, disease severity, and symptomatology Open
Background Cellular immune memory responses post coronavirus disease 2019 (COVID‐19) have been difficult to assess due to the risks of contaminating the immune response readout with memory responses stemming from previous exposure to endem…
View article: Duration of SARS-CoV-2 Immune Responses Up to Six Months Following Homologous or Heterologous Primary Immunization with ChAdOx1 nCoV-19 and BNT162b2 mRNA Vaccines
Duration of SARS-CoV-2 Immune Responses Up to Six Months Following Homologous or Heterologous Primary Immunization with ChAdOx1 nCoV-19 and BNT162b2 mRNA Vaccines Open
Heterologous primary immunization against SARS-CoV-2 is part of applied recommendations. However, little is known about duration of immune responses after heterologous vaccine regimens. To evaluate duration of immune responses after primar…
View article: SARS-CoV-2 induces a durable and antigen specific humoral immunity after asymptomatic to mild COVID-19 infection
SARS-CoV-2 induces a durable and antigen specific humoral immunity after asymptomatic to mild COVID-19 infection Open
Current SARS-CoV-2 serological assays generate discrepant results, and the longitudinal characteristics of antibodies targeting various antigens after asymptomatic to mild COVID-19 are yet to be established. This longitudinal cohort study …
View article: Impact of SARS‐CoV‐2 infection on vaccine‐induced immune responses over time
Impact of SARS‐CoV‐2 infection on vaccine‐induced immune responses over time Open
Objective To determine the long‐term impact of prior SARS‐CoV‐2 infection on immune responses after COVID‐19 vaccination. Methods Using longitudinally collected blood samples from the COMMUNITY study, we determined binding (WHO BAU mL −1 )…
View article: Impact of SARS-CoV-2 infection on vaccine-induced immune responses over time
Impact of SARS-CoV-2 infection on vaccine-induced immune responses over time Open
People with previous SARS-CoV-2 infection mount potent immune responses to COVID-19 vaccination, but long-term effects of prior infection on these immune responses are unknown. We investigated the long-term impact of prior SARS-CoV-2 infec…
View article: Robust humoral and cellular immune responses and low risk for reinfection at least 8 months following asymptomatic to mild COVID‐19
Robust humoral and cellular immune responses and low risk for reinfection at least 8 months following asymptomatic to mild COVID‐19 Open
Background Emerging data support detectable immune responses for months after severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection and vaccination, but it is not yet established to what degree and for how long protection …
View article: Neutralization of VOCs including Delta one year post COVID-19 or vaccine
Neutralization of VOCs including Delta one year post COVID-19 or vaccine Open
Background SARS-CoV-2 variants, such as Alpha, Beta, Gamma and Delta, are raising concern about the efficiency of neutralizing antibodies (NAb) induced by wild-type infection or vaccines based on the wild-type spike. Methods We determined …
View article: Antibody Responses After a Single Dose of ChAdOx1 nCoV-19 Vaccine in Healthcare Workers Previously Infected with SARS-CoV-2
Antibody Responses After a Single Dose of ChAdOx1 nCoV-19 Vaccine in Healthcare Workers Previously Infected with SARS-CoV-2 Open
Background Recent reports demonstrate robust serological responses to a single dose of messenger RNA (mRNA) vaccines in individuals previously infected with SARS-CoV-2. Data on immune responses following a single-dose adenovirus-vectored v…
View article: SARS-CoV-2 induces a durable and antigen specific humoral immunity after asymptomatic to mild COVID-19 infection
SARS-CoV-2 induces a durable and antigen specific humoral immunity after asymptomatic to mild COVID-19 infection Open
Current SARS-CoV-2 serological assays generate discrepant results, and the longitudinal characteristics of antibodies targeting various antigens after asymptomatic to mild COVID-19 are yet to be established. This longitudinal cohort study …
View article: Circulating Markers of Neutrophil Extracellular Traps Are of Prognostic Value in Patients With COVID-19
Circulating Markers of Neutrophil Extracellular Traps Are of Prognostic Value in Patients With COVID-19 Open
Objective: The full spectrum of coronavirus disease 2019 (COVID-19) infection ranges from asymptomatic to acute respiratory distress syndrome, characterized by hyperinflammation and thrombotic microangiopathy. The pathogenic mechanisms are…
View article: SARS-CoV-2 exposure, symptoms and seroprevalence in health care workers
SARS-CoV-2 exposure, symptoms and seroprevalence in health care workers Open
Background SARS-CoV-2 may pose an occupational health risk to health care workers, but the prevalence of infections in this population is unknown. We examined the seroprevalence of SARS-CoV-2 antibodies among health care workers at a large…
View article: BDNF val66met genotype is not associated with psychological distress: A cross-sectional study in Indonesian young adults
BDNF val66met genotype is not associated with psychological distress: A cross-sectional study in Indonesian young adults Open
Background The number of mental disorders has been increasing but has yet to receive sufficient attention. Healthcare students and professionals tend to have high stress burden. Finding the root cause of psychological distress is important…
View article: <p>Polymorphism Of The <em>APM1</em> Gene In Subjects With Central Obesity Related To Lower High-Density Lipoprotein Cholesterol</p>
Polymorphism Of The <em>APM1</em> Gene In Subjects With Central Obesity Related To Lower High-Density Lipoprotein Cholesterol Open
This finding suggests that the T allele of the APM1 SNP rs2241766 is dominant in the Bandung population, and subjects with the homozygous TT genotype have a higher incidence of metabolic disorder.
View article: Elav-Mediated Exon Skipping and Alternative Polyadenylation of the Dscam1 Gene Are Required for Axon Outgrowth
Elav-Mediated Exon Skipping and Alternative Polyadenylation of the Dscam1 Gene Are Required for Axon Outgrowth Open
Many metazoan genes express alternative long 3' UTR isoforms in the nervous system, but their functions remain largely unclear. In Drosophila melanogaster, the Dscam1 gene generates short and long (Dscam1-L) 3' UTR isoforms because of alte…
View article: Elav-mediated exon skipping and alternative polyadenylation of the <i>Dscam1</i> gene is required for axon outgrowth
Elav-mediated exon skipping and alternative polyadenylation of the <i>Dscam1</i> gene is required for axon outgrowth Open
Summary Many metazoan genes express alternative long 3′ UTR isoforms in the nervous system, but their functions remain largely unclear. In Drosophila melanogaster , the Dscam1 gene generates short and long ( Dscam1-L ) 3′ UTR isoforms due …
View article: Psychological Distress Induces Poor Sleep Quality: A Cross-Sectional Study of Pharmacy Students in Bandung City, Indonesia
Psychological Distress Induces Poor Sleep Quality: A Cross-Sectional Study of Pharmacy Students in Bandung City, Indonesia Open
Introduction: Poor subjective sleep quality in undergraduate students has not been widely studied in Bandung city, Indonesia. Poor sleep quality has been related to a number of risk factors for poor health outcomes. Objective: To analyze t…
View article: Polymorphism of pfcrt K76T and pfatpase6 S769N Genes in Malaria Patients at Teluk Bintuni Regency, Papua, Indonesia
Polymorphism of pfcrt K76T and pfatpase6 S769N Genes in Malaria Patients at Teluk Bintuni Regency, Papua, Indonesia Open
Indonesia is one of the country with the highest prevalence of malaria infections. In order to achieve malaria control as an act to support Millenium Development Goals, complete eradication of Plasmodium parasites needs to be conducted. Dr…
View article: Polymorphism of pfcrt K76T and pfatpase6 S769N in Malaria Patients at Teluk Bintuni Regency, Papua, Indonesia
Polymorphism of pfcrt K76T and pfatpase6 S769N in Malaria Patients at Teluk Bintuni Regency, Papua, Indonesia Open
Indonesia is one of the country with the highest prevalence of malaria infections. In order to achieve malaria control as an act to support Millenium Development Goals, complete eradication of Plasmodium parasites needs to be conducted. Dr…