Heping Lei
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View article: Modulating Micro-Arc Oxidation Coating Properties on 6061 Aluminum Alloy via OH− to F− Ion Ratio Optimization
Modulating Micro-Arc Oxidation Coating Properties on 6061 Aluminum Alloy via OH− to F− Ion Ratio Optimization Open
We investigate the influence of the NaOH to KF ratio in a silicate electrolyte on the corrosion resistance and tribological properties of micro-arc oxidation (MAO) coatings on a 6061 aluminum alloy. By optimizing the electrolyte compositio…
View article: The Effect of Oxidation Time on the Organization and Corrosion Performance of 6061 Aluminum Alloy Micro-Arc Oxidation Coatings
The Effect of Oxidation Time on the Organization and Corrosion Performance of 6061 Aluminum Alloy Micro-Arc Oxidation Coatings Open
This study investigates the influence of micro-arc oxidation (MAO) duration on the formation and characteristics of ceramic coatings on 6061 aluminum alloys. MAO treatments were conducted in a silicate-based electrolyte for varying duratio…
View article: Optimization of Process Parameters and Microstructure of CoCrFeNiTiAl High-Performance High-Entropy Alloy Coating
Optimization of Process Parameters and Microstructure of CoCrFeNiTiAl High-Performance High-Entropy Alloy Coating Open
CoCrFeNiTiAl high-entropy alloy coatings have been prepared by laser cladding technology based on response surface methodology (RSM). The results show that the effects of laser power, cladding speed, and pulse width on the dilution rate an…
View article: Update of Indoles: Promising molecules for ameliorating metabolic diseases
Update of Indoles: Promising molecules for ameliorating metabolic diseases Open
Obesity and metabolic disorders have gradually become public health-threatening problems. The metabolic disorder is a cluster of complex metabolic abnormalities which are featured by dysfunction in glucose and lipid metabolism, and results…
View article: Hirsutine ameliorates hepatic and cardiac insulin resistance in high-fat diet-induced diabetic mice and in vitro models
Hirsutine ameliorates hepatic and cardiac insulin resistance in high-fat diet-induced diabetic mice and in vitro models Open
Closely associated with type 2 diabetes mellitus (T2DM), hepatic steatosis and cardiac hypertrophy resulting from chronic excess intake can exacerbate insulin resistance (IR). The current study aims to investigate the pharmacological effec…
View article: UGT1A1 rs4148323 A Allele is Associated With Increased 2-Hydroxy Atorvastatin Formation and Higher Death Risk in Chinese Patients With Coronary Artery Disease
UGT1A1 rs4148323 A Allele is Associated With Increased 2-Hydroxy Atorvastatin Formation and Higher Death Risk in Chinese Patients With Coronary Artery Disease Open
It is widely accepted that genetic polymorphisms impact atorvastatin (ATV) metabolism, clinical efficacy, and adverse events. The objectives of this study were to identify novel genetic variants influencing ATV metabolism and outcomes in C…
View article: Genome‐wide association study of metabolites in patients with coronary artery disease identified novel metabolite quantitative trait loci
Genome‐wide association study of metabolites in patients with coronary artery disease identified novel metabolite quantitative trait loci Open
We performed a metabolome-based genome-wide association study (metaboGWAS) in a Chinese cohort with coronary artery disease (CAD). We identified seven novel metabolite quantitative trait loci (metaboQTLs) and revealed the possible clinical…
View article: Insights into the prognosis of lipidomic dysregulation for death risk in patients with coronary artery disease
Insights into the prognosis of lipidomic dysregulation for death risk in patients with coronary artery disease Open
Background Dyslipidaemia contributes to the progression of coronary artery disease (CAD) toward adverse outcomes. Plasma lipidomic measure may improve the prognostic performances of clinical endpoints of CAD. Our research is designed to id…
View article: High Plasma Exposure of Statins Associated With Increased Risk of Contrast-Induced Acute Kidney Injury in Chinese Patients With Coronary Artery Disease
High Plasma Exposure of Statins Associated With Increased Risk of Contrast-Induced Acute Kidney Injury in Chinese Patients With Coronary Artery Disease Open
The role of statins in reducing the incidence of contrast-induced acute kidney injury (CI-AKI) remains controversial. We sought to evaluate the association between CI-AKI and high plasma exposure of statins in coronary artery disease (CAD)…