2018-01-01
Tolerability of inhaled N-chlorotaurine in humans: a double-blind randomized phase I clinical study
2018-01-01 • Roland Arnitz, Markus Stein, P Bauer, Barbara Lanthaler, Herbert Jamnig, Sabine Scholl‐Bürgi, Katharina Stempfl-Al-Jazrawi, Hanno Ulmer, Bernhard B...
Background: N-chlorotaurine (NCT), a long-lived oxidant produced by human leukocytes, can be synthesized chemically and used topically as a well-tolerated antiseptic to different body regions including sensitive ones. The aim of this study was to test the tolerability of inhaled 1% NCT in aqueous solution upon repeated application. Methods: The study was performed double-blind and randomized with a parallel test group (1% NCT) and control group (0.9% NaCl as placebo). There were two Austrian centres involved, the …