Peter Herbert Kann
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View article: Spontaneous hypoglycemia: should we mind the gap? Long-term follow-up of healthy people who met Whipple’s triad criteria
Spontaneous hypoglycemia: should we mind the gap? Long-term follow-up of healthy people who met Whipple’s triad criteria Open
Context Patients discharged as “healthy” with the symptoms of spontaneous hypoglycemia, commonly known as Whipple’s triad, need more attention. Objective Characterization and long-term follow-up of symptom development in patients with spon…
View article: Relevance of Endoscopic Ultrasound in Endocrinology Today: Multiple Endocrine Neoplasia Type 1, Insulinoma, Primary Aldosteronism—An Expert’s Perspective Based on Three Decades of Scientific and Clinical Experience
Relevance of Endoscopic Ultrasound in Endocrinology Today: Multiple Endocrine Neoplasia Type 1, Insulinoma, Primary Aldosteronism—An Expert’s Perspective Based on Three Decades of Scientific and Clinical Experience Open
In endocrinology, endoscopic ultrasound (EUS) may be used to image the adrenals, the endocrine pancreas, and other organs where endocrine neoplasms may occur. During the recent decades, EUS has been established predominantly to assess mult…
View article: Spontaneous hypoglycemia: Should we mind the gap? Long-term follow-up of healthy people who met Whipple´s Triad
Spontaneous hypoglycemia: Should we mind the gap? Long-term follow-up of healthy people who met Whipple´s Triad Open
Context: Patients discharged as “healthy” with the symptom of spontaneous hypoglycemia need more attention. Objective Characterization and long-term follow-up of these patients Methods Retrospective analysis and questionnaire follow-up Set…
View article: Two Case Reports of Subacute Thyroiditis after Receiving Vaccine for COVID-19
Two Case Reports of Subacute Thyroiditis after Receiving Vaccine for COVID-19 Open
The ongoing COVID-19 pandemic, caused by a coronavirus named SARS-CoV-2, has struck the planet with great force. As of December 2019, the virus has made its devasting route across all continents . In January 2022, the World Health Organiza…
View article: Pancreaticoduodenectomy Is the Best Surgical Procedure for Zollinger–Ellison Syndrome Associated with Multiple Endocrine Neoplasia Type 1
Pancreaticoduodenectomy Is the Best Surgical Procedure for Zollinger–Ellison Syndrome Associated with Multiple Endocrine Neoplasia Type 1 Open
Aim: The aim of this research was to evaluate the long-term outcome of pancreaticoduodenectomy (PD) versus other duodenopancreatic resections (non-PD) for the surgical treatment of the Zollinger–Ellison syndrome (ZES) in patients with mult…
View article: Pheochromocytoma and Adrenocortical Carcinoma: Morphological Characteristics in Endoscopic Ultrasound Imaging
Pheochromocytoma and Adrenocortical Carcinoma: Morphological Characteristics in Endoscopic Ultrasound Imaging Open
Purpose Pheochromocytoma (PCC) and adrenocortical carcinoma (ACC) are two rare endocrine diseases. Early diagnosis is crucial to significantly reduce morbidity and mortality. In this study, we used endoscopic ultrasound (EUS) for high-reso…
View article: The Effect of Obstructive Sleep Apnea and Continuous Positive Airway Pressure Therapy on Skeletal Muscle Lipid Content in Obese and Nonobese Men
The Effect of Obstructive Sleep Apnea and Continuous Positive Airway Pressure Therapy on Skeletal Muscle Lipid Content in Obese and Nonobese Men Open
Obstructive sleep apnea (OSA), independently of obesity (OBS), predisposes to insulin resistance (IR) for largely unknown reasons. Because OSA-related intermittent hypoxia triggers lipolysis, overnight increases in circulating free fatty a…
View article: Gender Differences in Multiple Endocrine Neoplasia Type 1: Implications for Screening?
Gender Differences in Multiple Endocrine Neoplasia Type 1: Implications for Screening? Open
Background: Some gender-related differences have been reported in multiple endocrine neoplasia type 1 (MEN1), although not all reports are conclusive. This systematic review with analysis of the own MEN1 cohort evaluates gender differences…
View article: The effects of prolonged single night session of videogaming on sleep and declarative memory
The effects of prolonged single night session of videogaming on sleep and declarative memory Open
Use of electronic media is widespread among adolescents. Many male adolescents spend a major part of their evenings playing video games. The increased exposure to artificial light as well as the exciting nature of this pastime is under sus…
View article: Surgical Management, Preoperative Tumor Localization, and Histopathology of 80 Patients Operated on for Insulinoma
Surgical Management, Preoperative Tumor Localization, and Histopathology of 80 Patients Operated on for Insulinoma Open
Introduction Diagnosis and pathological classification of insulinomas are challenging. Aim To characterize localization of tumors, surgery outcomes, and histopathology in patients with insulinoma. Methods Patients with surgically resected …
View article: Clinicopathological hallmarks and biomarkers of colorectal neuroendocrine neoplasms
Clinicopathological hallmarks and biomarkers of colorectal neuroendocrine neoplasms Open
Chromogranin A (CgA) is a well-established marker for diagnosis and follow up of patients with gastroenteropancreatic neuroendocrine neoplasms (GEP-NEN). Recently, it has been shown that plasma levels of CgA correlate with tumor load and p…
View article: Gender-, age- and time-dependent dosing of growth hormone in adults – real-world data from a decade of clinical practice in Germany
Gender-, age- and time-dependent dosing of growth hormone in adults – real-world data from a decade of clinical practice in Germany Open
We evaluated treatment patterns and gender-dependent dosing of growth hormone (GH) substitution in adults with GH deficiency (AGHD). Data on GH dose were collected (2003–2013) from 509 GH-treated patients (mean age: 48.9 years; 47% female)…
View article: Clinical and Laboratory Evaluation of a New Specific Point-of-Care Test for Intact Proinsulin
Clinical and Laboratory Evaluation of a New Specific Point-of-Care Test for Intact Proinsulin Open
Background: Intact proinsulin is a biomarker for pancreatic ß-cell dysfunction. In large prospective studies in nondiabetic subjects, elevated intact proinsulin predicted development of type 2 diabetes and/or macrovascular events up to 7 y…
View article: An unusual phenotype of MEN1 syndrome with a SI-NEN associated with a deletion of the MEN1 gene
An unusual phenotype of MEN1 syndrome with a SI-NEN associated with a deletion of the MEN1 gene Open
Summary We report about a young female who developed an unusual and an aggressive phenotype of the MEN1 syndrome characterized by the development of a pHPT, malignant non-functioning pancreatic and duodenal neuroendocrine neoplasias, a pit…