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View article: 89P BIMAP: Breast cancer intra-operative margin assessment using PET-CT
89P BIMAP: Breast cancer intra-operative margin assessment using PET-CT Open
View article: Menopause hormone therapy significantly alters pathophysiological biomarkers of Alzheimer's disease
Menopause hormone therapy significantly alters pathophysiological biomarkers of Alzheimer's disease Open
Introduction This increasing body of literature indicates that menopause hormonal replacement therapy (MHT) may substantially mitigate the risk of developing late‐life cognitive decline due to progressive Alzheimer's disease (AD) pathophys…
View article: Establishment of reference values for plasma neurofilament light based on healthy individuals aged 5–90 years
Establishment of reference values for plasma neurofilament light based on healthy individuals aged 5–90 years Open
The recent development of assays that accurately quantify neurofilament light, a neuronal cytoskeleton protein, in plasma has generated a vast literature supporting that it is a sensitive, dynamic, and robust biomarker of neuroaxonal damag…
View article: Prolonged recombinant pregnancy hormone use in BRCA1 and BRCA2 mutation carriers
Prolonged recombinant pregnancy hormone use in BRCA1 and BRCA2 mutation carriers Open
Background An early first full-time pregnancy substantially reduces the risk of developing breast cancer later in life. Extensive studies indicate that this protective effect is mediated by the pregnancy hormone human chorionic gonadotroph…
View article: β-Secretase1 biological markers for Alzheimer’s disease: state-of-art of validation and qualification
β-Secretase1 biological markers for Alzheimer’s disease: state-of-art of validation and qualification Open
View article: Differential default mode network trajectories in asymptomatic individuals at risk for Alzheimer's disease
Differential default mode network trajectories in asymptomatic individuals at risk for Alzheimer's disease Open
Introduction The longitudinal trajectories of functional brain dynamics and the impact of genetic risk factors in individuals at risk for Alzheimer's disease are poorly understood. Methods In a large‐scale monocentric cohort of 224 amyloid…
View article: Breast Lymphoma
Breast Lymphoma Open
Teaching point: Primary breast lymphoma is a rare disease, especially in males, but should be considered in the differential diagnosis of a breast mass because of the different treatment and prognosis.
View article: Exploratory analysis of the human breast DNA methylation profile upon soymilk exposure
Exploratory analysis of the human breast DNA methylation profile upon soymilk exposure Open
Upon soy consumption, isoflavone metabolites attain bioactive concentrations in breast tissue possibly affecting health. Though in vitro epigenetic activity of soy metabolites has been described, the in vivo impact on the epigenome is larg…
View article: Precision medicine and drug development in Alzheimer’s disease: the importance of sexual dimorphism and patient stratification
Precision medicine and drug development in Alzheimer’s disease: the importance of sexual dimorphism and patient stratification Open