Hermann Aberle
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View article: Formin 3 stabilizes the cytoskeleton of <i>Drosophila</i> tendon cells, thus enabling them to resist muscle tensile forces
Formin 3 stabilizes the cytoskeleton of <i>Drosophila</i> tendon cells, thus enabling them to resist muscle tensile forces Open
The cytoskeleton of Drosophila tendon cells features specialized F-actin and microtubule arrays that endow these cells with resistance to the tensile forces exerted by the attached muscles. In a forward genetic screen for mutants with neur…
View article: Molecular insights into the axon guidance molecules Sidestep and Beaten path
Molecular insights into the axon guidance molecules Sidestep and Beaten path Open
The transmembrane protein Sidestep (Side) functions as a substrate-bound attractant for motor axons in Drosophila . Outgrowing motor axons recognize Side via Beaten path Ia (Beat) and migrate along Side-expressing tissues. Here, we report …
View article: Rearrangements in the musculature correlate with jumping behaviour in legless Mediterranean fruit fly larvae Ceratitis capitata (Tephritidae)
Rearrangements in the musculature correlate with jumping behaviour in legless Mediterranean fruit fly larvae Ceratitis capitata (Tephritidae) Open
Larvae of holometabolic insects evolved different crawling strategies depending on the presence or absence of larval legs or life style. A rather unusual mode of locomotion has independently evolved in legless larvae of several dipteran sp…
View article: Dynamic monitoring of vital functions and tissue re-organization in Saturnia pavonia (Lepidoptera, Saturniidae) during final metamorphosis by non-invasive MRI
Dynamic monitoring of vital functions and tissue re-organization in Saturnia pavonia (Lepidoptera, Saturniidae) during final metamorphosis by non-invasive MRI Open
Magnetic resonance imaging (MRI) is the key whole-body imaging technology for observing processes within a living object providing excellent resolution and contrast between soft tissues. In the present work, we exploited the non-destructiv…
View article: Misregulation of Drosophila Sidestep Leads to Uncontrolled Wiring of the Adult Neuromuscular System and Severe Locomotion Defects
Misregulation of Drosophila Sidestep Leads to Uncontrolled Wiring of the Adult Neuromuscular System and Severe Locomotion Defects Open
Holometabolic organisms undergo extensive remodelling of their neuromuscular system during metamorphosis. Relatively, little is known whether or not the embryonic guidance of molecules and axonal growth mechanisms are re-activated for the …
View article: Axon Guidance and Collective Cell Migration by Substrate-Derived Attractants
Axon Guidance and Collective Cell Migration by Substrate-Derived Attractants Open
Neurons have evolved specialized growth structures to reach and innervate their target cells. These growth cones express specific receptor molecules that sense environmental cues and transform them into steering decisions. Historically, va…
View article: Sidestep-induced neuromuscular miswiring causes severe locomotion defects in <i>Drosophila</i> larvae
Sidestep-induced neuromuscular miswiring causes severe locomotion defects in <i>Drosophila</i> larvae Open
Mutations in motor axon guidance molecules cause aberrant projection patterns of motor nerves. As most studies in Drosophila have analysed these molecules in fixed embryos, the consequences for larval locomotion are entirely unexplored. He…
View article: Correction: Corrigendum: Impaired protein translation in Drosophila models for Charcot–Marie–Tooth neuropathy caused by mutant tRNA synthetases
Correction: Corrigendum: Impaired protein translation in Drosophila models for Charcot–Marie–Tooth neuropathy caused by mutant tRNA synthetases Open
View article: Impaired protein translation in Drosophila models for Charcot–Marie–Tooth neuropathy caused by mutant tRNA synthetases
Impaired protein translation in Drosophila models for Charcot–Marie–Tooth neuropathy caused by mutant tRNA synthetases Open
View article: Hierarchical Microtubule Organization Controls Axon Caliber and Transport and Determines Synaptic Structure and Stability
Hierarchical Microtubule Organization Controls Axon Caliber and Transport and Determines Synaptic Structure and Stability Open