Hermann Neitz
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View article: Trapped in translocation – Stalling of XPD on a crosslinked DNA substrate
Trapped in translocation – Stalling of XPD on a crosslinked DNA substrate Open
The super family 2 (SF2) helicase XPD is a central component of the general transcription factor II H (TFIIH) which is essential for transcription and nucleotide excision DNA repair (NER) 1 . Within these two processes XPDs helicase functi…
A tolane-modified 5-ethynyluridine as a universal and fluorogenic photochemical DNA crosslinker Open
A new photoinduced fluorogenic interstrand crosslinking reaction is reported in three different DNA architectures using the hydrophobic tolane-containing nucleoside Tol dU.
Tailored Tolane‐Perfluorotolane Assembly as Supramolecular Base Pair Replacement in DNA Open
Arene‐fluoroarene interactions offer outstanding possibilities for engineering of supramolecular systems, including nucleic acids. Here, we implement the tolane‐perfluorotolane interaction as base pair replacement in DNA. Tolane (THH) and …
Tailored Tolane‐Perfluorotolane Assembly as Supramolecular Base Pair Replacement in DNA Open
Arene‐fluoroarene interactions offer outstanding possibilities for engineering of supramolecular systems, including nucleic acids. Here, we implement the tolane‐perfluorotolane interaction as base pair replacement in DNA. Tolane (THH) and …
Identification of novel functional mini-receptors by combinatorial screening of split-WW domains Open
A combinatorial approach toward novel functional WW domains based on coiled-coil-mediated reconstitution of split WW domains is presented. As such, an ATP-binding WW domain was found from a 4-by-6 library of N- and C-terminal WW domain fra…