Hernando Santamaría‐García
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View article: Patient- and caregiver-subjective memory complaints are associated with sociodemographic and clinical factors in neurocognitive disorders
Patient- and caregiver-subjective memory complaints are associated with sociodemographic and clinical factors in neurocognitive disorders Open
View article: Creative experiences and brain clocks
Creative experiences and brain clocks Open
View article: Cardiovascular risk factors and the allostatic interoceptive network in dementia
Cardiovascular risk factors and the allostatic interoceptive network in dementia Open
Aims Cardiovascular risk factors, such diabetes, hypertension, blood pressure, obesity, and smoking, are linked with allostatic-interoception—the continuous monitoring of internal bodily states in anticipation of environmental demands. The…
View article: Social exposome and brain health outcomes of dementia across Latin America
Social exposome and brain health outcomes of dementia across Latin America Open
A multidimensional social exposome (MSE)—the combined lifespan measures of education, food insecurity, financial status, access to healthcare, childhood experiences, and more—may shape dementia risk and brain health over the lifespan, part…
View article: Chronic pain in the Chilean population: risk factors prevalence and cognitive associations
Chronic pain in the Chilean population: risk factors prevalence and cognitive associations Open
Chronic pain (CP) is a global public health issue and a critical factor in the aging process. Chile, as one of the most aged countries in Latin America, presents a unique context for exploring CP and its associated factors. Despite its sig…
View article: Subjective memory complaints of patients and caregivers and their association with sociodemographic and clinical factors in patients with neurocognitive disorders from Colombia
Subjective memory complaints of patients and caregivers and their association with sociodemographic and clinical factors in patients with neurocognitive disorders from Colombia Open
View article: Source-space EEG Alpha Activity Reveals Brain Age Gaps Due to Neurodegeneration and Disparity
Source-space EEG Alpha Activity Reveals Brain Age Gaps Due to Neurodegeneration and Disparity Open
This study examined whether the brain age gap (BAG), the difference between chronological and predicted brain age, reflects neurodegeneration when estimated from electroencephalographic resting-state (rsEEG) α-oscillations. It also explore…
View article: DNA methylation age from peripheral blood predicts progression to Alzheimer’s disease, white matter disease burden, and cortical atrophy
DNA methylation age from peripheral blood predicts progression to Alzheimer’s disease, white matter disease burden, and cortical atrophy Open
Cross-sectional studies suggest a limited relationship between accelerated epigenetic aging derived from epigenetic clocks, and Alzheimer’s disease (AD) pathophysiology or risk. However, most prior analyses have not utilized longitudinal a…
View article: The effect of childhood trauma on bipolar depression
The effect of childhood trauma on bipolar depression Open
View article: 1278 Feasibility of 48-h Ambulatory BP Assessment in Latinos with Dementia
1278 Feasibility of 48-h Ambulatory BP Assessment in Latinos with Dementia Open
Introduction Ambulatory blood pressure (BP) monitoring encapsulates 24-h BP patterns across the sleep-wake cycle and provides a comprehensive assessment of BP regulation with certain features, such as sleep-time dipping, that can better pr…
View article: Impaired interoception in Colombian victims of armed conflict with PTSD: a preliminary HEP study
Impaired interoception in Colombian victims of armed conflict with PTSD: a preliminary HEP study Open
Individuals who have been exposed to violence are at high risk of developing mental health problems, particularly posttraumatic stress disorder (PTSD). A prominent example is the experience of Colombia, which has suffered systemic violence…
View article: Qualitative and quantitative educational disparities and brain signatures in healthy aging and dementia across global settings
Qualitative and quantitative educational disparities and brain signatures in healthy aging and dementia across global settings Open
View article: Critical Review of the Methodological Shortcoming of Ambulatory Blood Pressure Monitoring and Cognitive Function Studies
Critical Review of the Methodological Shortcoming of Ambulatory Blood Pressure Monitoring and Cognitive Function Studies Open
Growing evidence suggests that abnormal diurnal blood pressure rhythms may be associated with many adverse health outcomes, including increased risk of cognitive impairment and dementia. This study evaluates methodological aspects of resea…
View article: Alpha rhythm and Alzheimer’s disease: Has Hans Berger’s dream come true?
Alpha rhythm and Alzheimer’s disease: Has Hans Berger’s dream come true? Open
In this "centenary" paper, an expert panel revisited Hans Berger's groundbreaking discovery of human restingstate electroencephalographic (rsEEG) alpha rhythms (8-12 Hz) in 1924, his foresight of substantial clinical applications in patien…
View article: Social and health disparities associated with healthy brain ageing in Brazil and in other Latin American countries
Social and health disparities associated with healthy brain ageing in Brazil and in other Latin American countries Open
For the Portuguese and Spanish translations of the abstract see Supplementary Materials section.
View article: Effects of Step Length and Stride Variation During Forward Lunges on Lower-Extremity Muscle Activity
Effects of Step Length and Stride Variation During Forward Lunges on Lower-Extremity Muscle Activity Open
Background: The forward lunge is a closed-chain weight-bearing multi-joint exercise simulating the activities of daily living, such as walking or stair climbing, which mainly activates hip, knee, and ankle musculature and is also used by a…
View article: Chronic Pain in Latin America: Prevalence, Risk Factors, and Their Association with Dementia
Chronic Pain in Latin America: Prevalence, Risk Factors, and Their Association with Dementia Open
Background Chronic pain (CP) is defined as the persistence of pain beyond the expected recovery period of an injury, or alternatively, with a duration exceeding three months. It has been recognized as a risk factor for dementia in European…
View article: Socioeconomic and health‐related disparities associated with healthy brain aging in Latin American countries
Socioeconomic and health‐related disparities associated with healthy brain aging in Latin American countries Open
Background Latin American Countries (LACs) have major health‐related inequities due to historical, cultural, and social aspects. These factors have been suggested as important determinants of healthy aging in LACs. Here, we evaluated class…
View article: Epigenetics of dementia remains unraveled in Latin American and Caribbean populations: A call for collaborative efforts
Epigenetics of dementia remains unraveled in Latin American and Caribbean populations: A call for collaborative efforts Open
View article: Critical Review of the Methodological Shortcomings of Ambulatory Blood Pressure Monitoring and Cognitive Function Studies
Critical Review of the Methodological Shortcomings of Ambulatory Blood Pressure Monitoring and Cognitive Function Studies Open
Growing evidence suggests that abnormal diurnal blood pressure rhythms may be associated with many adverse health outcomes including increased risk of cognitive impairment and dementia. This study evaluates methodological aspects of resear…
View article: DNA methylation age from peripheral blood predicts progression to Alzheimer’s disease, white matter disease burden, and cortical atrophy
DNA methylation age from peripheral blood predicts progression to Alzheimer’s disease, white matter disease burden, and cortical atrophy Open
Cross-sectional studies suggest a limited relationship between accelerated epigenetic aging derived from epigenetic clocks, and Alzheimer’s disease (AD) pathophysiology or risk. However, most prior analyses have not utilized longitudinal a…
View article: Francisco Lopera (1951–2024)
Francisco Lopera (1951–2024) Open
View article: Structural inequality and temporal brain dynamics across diverse samples
Structural inequality and temporal brain dynamics across diverse samples Open
Background Structural income inequality – the uneven income distribution across regions or countries – could affect brain structure and function, beyond individual differences. However, the impact of structural income inequality on the bra…
View article: Author Correction: Brain clocks capture diversity and disparities in aging and dementia across geographically diverse populations
Author Correction: Brain clocks capture diversity and disparities in aging and dementia across geographically diverse populations Open
View article: Brain clocks capture diversity and disparities in aging and dementia across geographically diverse populations
Brain clocks capture diversity and disparities in aging and dementia across geographically diverse populations Open
View article: Educational disparities in brain health and dementia across Latin America and the United States
Educational disparities in brain health and dementia across Latin America and the United States Open
BACKGROUND Education influences brain health and dementia. However, its impact across regions, specifically Latin America (LA) and the United States (US), is unknown. METHODS A total of 1412 participants comprising controls, patients with …
View article: Allostatic Interoceptive Overload Across Psychiatric and Neurological Conditions
Allostatic Interoceptive Overload Across Psychiatric and Neurological Conditions Open
Emerging theories emphasize the crucial role of allostasis (anticipatory and adaptive regulation of the body's biological processes) and interoception (integration, anticipation, and regulation of internal bodily states) in adjusting physi…
View article: Brain clocks capture diversity and disparity in aging and dementia
Brain clocks capture diversity and disparity in aging and dementia Open
View article: Healthy aging meta-analyses and scoping review of risk factors across Latin America reveal large heterogeneity and weak predictive models
Healthy aging meta-analyses and scoping review of risk factors across Latin America reveal large heterogeneity and weak predictive models Open
View article: Brain health in diverse settings: How age, demographics and cognition shape brain function
Brain health in diverse settings: How age, demographics and cognition shape brain function Open