Hongda Pan
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View article: Development and validation of a cancer-associated fibroblast-derived lncRNA signature for predicting clinical outcomes in colorectal cancer
Development and validation of a cancer-associated fibroblast-derived lncRNA signature for predicting clinical outcomes in colorectal cancer Open
Cancer-associated fibroblasts (CAFs) are actively involved in cancer progression through generating extracellular matrix and orchestrating the crosstalk within the tumor microenvironment (TME). This study aimed to develop and validate a CA…
View article: Corrigendum: EXOSC5 as a Novel Prognostic Marker Promotes Proliferation of Colorectal Cancer via Activating the ERK and AKT Pathways
Corrigendum: EXOSC5 as a Novel Prognostic Marker Promotes Proliferation of Colorectal Cancer via Activating the ERK and AKT Pathways Open
Error in Figure/TableIn the original article, there were mistakes in Figure 2 as published. In Figure 2D and F, an unintentional error occurred upon using Adobe Illustrator to organize the images, and incorrect images of the colony formati…
View article: Supplementary Material for: A Chinese Case of X-Linked Acrogigantism and Systematic Review
Supplementary Material for: A Chinese Case of X-Linked Acrogigantism and Systematic Review Open
Introduction: This study described a Chinese case of X-linked acrogigantism (X-LAG) and summarized the characteristics and treatment of all reported cases. Methods: Clinical materials and biological samples from a 5-year and 2-month-old fe…
View article: Survival-Associated Alternative Splicing Events and Prognostic Signatures in Pancreatic Cancer
Survival-Associated Alternative Splicing Events and Prognostic Signatures in Pancreatic Cancer Open
The survival-associated AS events and prognostic signatures identified in this study can serve as useful tool for predicting prognosis of patients with PC. Moreover, the SF-AS regulatory networks may provide clues for the mechanisms underl…
View article: Development and Validation of an m6A RNA Methylation Regulator-Based Signature for Prognostic Prediction in Cervical Squamous Cell Carcinoma
Development and Validation of an m6A RNA Methylation Regulator-Based Signature for Prognostic Prediction in Cervical Squamous Cell Carcinoma Open
Background: Cervical squamous cell carcinoma (CESC) is one of the most common causes of cancer-related death worldwide. N6-methyladenosine (m6A) plays an important role in various cellular responses by regulating mRNA biology. This study a…
View article: <p>Construction and Validation of an m6A RNA Methylation Regulators-Based Prognostic Signature for Esophageal Cancer</p>
Construction and Validation of an m6A RNA Methylation Regulators-Based Prognostic Signature for Esophageal Cancer Open
Our study constructed and validated an m6A RNA methylation regulators-based prognostic signature. This might provide important information for developing diagnostic and therapeutic strategies.
View article: Prognostic significance of preoperative plasma fibrinogen levels in primary gastrointestinal stromal tumours: a retrospective cohort study
Prognostic significance of preoperative plasma fibrinogen levels in primary gastrointestinal stromal tumours: a retrospective cohort study Open
Background Improved prediction of prognosis for gastrointestinal stromal tumours (GISTs) has become increasingly important since the introduction of small molecule tyrosine kinase inhibitors. Here, we aimed to evaluate the prognostic signi…
View article: Construction of a Competitive Endogenous RNA Network and Identification of Potential Regulatory Axis in Gastric Cancer
Construction of a Competitive Endogenous RNA Network and Identification of Potential Regulatory Axis in Gastric Cancer Open
Background: Increasing studies has found that long non-coding RNAs (lncRNAs) play critical roles in carcinogenesis, but the underlying mechanisms remain unclear. The aim of this study is to construct a competitive endogenous RNA (ceRNA) ne…
View article: EXOSC5 as a Novel Prognostic Marker Promotes Proliferation of Colorectal Cancer via Activating the ERK and AKT Pathways
EXOSC5 as a Novel Prognostic Marker Promotes Proliferation of Colorectal Cancer via Activating the ERK and AKT Pathways Open
Background and Objective: Exosome component 5 (EXOSC5) is a novel cancer-related gene that is aberrantly expressed in various malignances. However, the molecular mechanism and biological role of EXOSC5 have not been explored in colorectal …
View article: Identification and development of long non‐coding RNA‐associated regulatory network in colorectal cancer
Identification and development of long non‐coding RNA‐associated regulatory network in colorectal cancer Open
Colorectal cancer (CRC) is one of the leading causes of cancer‐associated death globally. Long non‐coding RNAs (lncRNAs) have been identified as micro RNA (miRNA) sponges in a competing endogenous RNA (ceRNA) network and are involved in th…
View article: MicroRNA‑423‑5p inhibits colon cancer growth by promoting caspase‑dependent apoptosis
MicroRNA‑423‑5p inhibits colon cancer growth by promoting caspase‑dependent apoptosis Open
Plasma microRNA (miR)-423-5p is a potential biomarker for the detection of colon cancer. However, the expression and biological role of miR-423-5p in colon tumorigenesis remains unclear. In the current study, reverse transcription-quantita…
View article: The quality of total mesorectal excision specimen: A review of its macroscopic assessment and prognostic significance
The quality of total mesorectal excision specimen: A review of its macroscopic assessment and prognostic significance Open
As a surgical procedure which could significantly lower the recurrence rate of cancers, total mesorectal excision (TME) has been the gold standard for middle and lower rectal cancer treatment. However, previous studies have shown that the …
View article: Pulmonary metastasis in rectal cancer: a retrospective study of clinicopathological characteristics of 404 patients in Chinese cohort
Pulmonary metastasis in rectal cancer: a retrospective study of clinicopathological characteristics of 404 patients in Chinese cohort Open
Objectives This study aim to investigate the incidence, timing and risk factors of metachronous pulmonary recurrence after curative resection in patients with rectal cancer. Design A retrospective cohort study. Setting This study was condu…
View article: High levels of serum platelet-derived growth factor-AA and human epidermal growth factor receptor-2 are predictors of colorectal cancer liver metastasis
High levels of serum platelet-derived growth factor-AA and human epidermal growth factor receptor-2 are predictors of colorectal cancer liver metastasis Open
PDGFAA in tumor drainage and HER2 in PV blood may be useful predictive factors for synchronous liver metastasis of colorectal cancer.