Hervé Seligmann
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View article: Viroviroids of giant viruses expand the spectrum of hosts of the smallest parasites
Viroviroids of giant viruses expand the spectrum of hosts of the smallest parasites Open
The evolution of organisms is partly linked to parasitism by transposons or their equivalents. Viroids, the smallest pathogens, have been described in plants. They consist of circular stem-loop hairpin-containing RNA sequences. Recently vi…
View article: The application of ARIMA model to analyze COVID-19 incidence pattern in several countries
The application of ARIMA model to analyze COVID-19 incidence pattern in several countries Open
International audience
View article: Estimation of Daily Reproduction Numbers during the COVID-19 Outbreak
Estimation of Daily Reproduction Numbers during the COVID-19 Outbreak Open
(1) Background: The estimation of daily reproduction numbers throughout the contagiousness period is rarely considered, and only their sum R0 is calculated to quantify the contagiousness level of an infectious disease. (2) Methods: We prov…
View article: Unpredictable, Counter-Intuitive Geoclimatic and Demographic Correlations of COVID-19 Spread Rates
Unpredictable, Counter-Intuitive Geoclimatic and Demographic Correlations of COVID-19 Spread Rates Open
We present spread parameters for first and second waves of the COVID-19 pandemic for USA states, and for consecutive nonoverlapping periods of 20 days for the USA and 51 countries across the globe. We studied spread rates in the USA states…
View article: Geoclimatic, demographic and socio-economic determinants of the Covid-19 prevalence
Geoclimatic, demographic and socio-economic determinants of the Covid-19 prevalence Open
<p>We propose a panorama of already known Covid-19 determinants and some other new factors depending on three families of variables, i.e., geoclimatic (like temperature or elevation), demographic (like population density or median ag…
View article: Balanced evaluation of preliminary data on a candidate COVID-19 hydroxychloroquine treatment
Balanced evaluation of preliminary data on a candidate COVID-19 hydroxychloroquine treatment Open
View article: Estimation of Daily Reproduction rates in COVID-19 Outbreak
Estimation of Daily Reproduction rates in COVID-19 Outbreak Open
(1) Background The estimation of daily reproduction rates throughout the infectivity period is rarely considered and only their sum R o is calculated to quantify the level of virulence of an infectious agent; (2) Methods We give the equati…
View article: Combinatorial Fusion Rules to Describe Codon Assignment in the Standard Genetic Code
Combinatorial Fusion Rules to Describe Codon Assignment in the Standard Genetic Code Open
We propose combinatorial fusion rules that describe the codon assignment in the standard genetic code simply and uniformly for all canonical amino acids. These rules become obvious if the origin of the standard genetic code is considered a…
View article: SARS-CoV-2 and miRNA-like inhibition power
SARS-CoV-2 and miRNA-like inhibition power Open
View article: Summer COVID-19 third wave: faster high altitude spread suggests high UV adaptation
Summer COVID-19 third wave: faster high altitude spread suggests high UV adaptation Open
We present spread parameters for first and second waves of the COVID-19 pandemy for USA states, and third wave for 32 regions (19 countries and 13 states of the USA) detected beginning of August 2020. USA first/second wave spreads increase…
View article: Inverted Covariate Effects for First versus Mutated Second Wave Covid-19: High Temperature Spread Biased for Young
Inverted Covariate Effects for First versus Mutated Second Wave Covid-19: High Temperature Spread Biased for Young Open
(1) Background: Here, we characterize COVID-19’s waves, following a study presenting negative associations between first wave COVID-19 spread parameters and temperature. (2) Methods: Visual examinations of daily increases in confirmed COVI…
View article: Inverted covariate effects for mutated 2<sup>nd</sup> vs 1<sup>st</sup> wave Covid-19: high temperature spread biased for young
Inverted covariate effects for mutated 2<sup>nd</sup> vs 1<sup>st</sup> wave Covid-19: high temperature spread biased for young Open
(1) Background Here, we characterize COVID-19 2 nd waves, following a study presenting negative associations between 1 st wave COVID-19 spread parameters and temperature; (2) Methods Visual examinations of daily increase in confirmed COVID…
View article: Theoretical minimal RNA rings mimick molecular evolution before tRNA-mediated translation: codon-amino acid affinities increase from early to late RNA rings
Theoretical minimal RNA rings mimick molecular evolution before tRNA-mediated translation: codon-amino acid affinities increase from early to late RNA rings Open
Nucleotide affinities for noncovalent interactions with amino acids produce associations between mRNAs and cognate peptides, potentially regulating ribosomal translation. Correlations between nucleotide affinities and residue hydrophobicit…
View article: Comparisons between small ribosomal RNA and theoretical minimal RNA ring secondary structures confirm phylogenetic and structural accretion histories
Comparisons between small ribosomal RNA and theoretical minimal RNA ring secondary structures confirm phylogenetic and structural accretion histories Open
View article: Temperature Decreases Spread Parameters of the New Covid-19 Case Dynamics
Temperature Decreases Spread Parameters of the New Covid-19 Case Dynamics Open
(1) Background: The virulence of coronavirus diseases due to viruses like SARS-CoV or MERS-CoV decreases in humid and hot weather. The putative temperature dependence of infectivity by the new coronavirus SARS-CoV-2 or covid-19 has a high …
View article: Systematic Nucleotide Exchange Analysis of ESTs From the Human Cancer Genome Project Report: Origins of 347 Unknown ESTs Indicate Putative Transcription of Non-Coding Genomic Regions
Systematic Nucleotide Exchange Analysis of ESTs From the Human Cancer Genome Project Report: Origins of 347 Unknown ESTs Indicate Putative Transcription of Non-Coding Genomic Regions Open
Expressed sequence tags (ESTs) provide an imprint of cellular RNA diversity irrespectively of sequence homology with template genomes. NCBI databases include many unknown RNAs from various normal and cancer cells. These are usually ignored…
View article: Accretion history of large ribosomal subunits deduced from theoretical minimal RNA rings is congruent with histories derived from phylogenetic and structural methods
Accretion history of large ribosomal subunits deduced from theoretical minimal RNA rings is congruent with histories derived from phylogenetic and structural methods Open
View article: The primordial tRNA acceptor stem code from theoretical minimal RNA ring clusters
The primordial tRNA acceptor stem code from theoretical minimal RNA ring clusters Open
View article: Codon Directional Asymmetry Suggests Swapped Prebiotic 1st and 2nd Codon Positions
Codon Directional Asymmetry Suggests Swapped Prebiotic 1st and 2nd Codon Positions Open
Background: Codon directional asymmetry (CDA) classifies the 64 codons into palindromes (XYX, CDA = 0), and 5′- and 3′-dominant (YXX and XXY, CDA < 0 and CDA > 0, respectively). Previously, CDA was defined by the purine/pyrimidine divide (…
View article: La température diminue les paramètres de la dynamique de propagation des nouveaux cas de Covid-19
La température diminue les paramètres de la dynamique de propagation des nouveaux cas de Covid-19 Open
(1) Contexte: La virulence des maladies a coronavirus dues a des virus comme le SRAS-CoV ou le MERS-CoV diminue par temps humide et chaud. La dependance putative de l'infectiosite a la temperature pour le nouveau coronavirus SARS-CoV-2 ou …
View article: Des ARNs circulaires possibles chaînons de l’évolution de la traduction médiée par les ARNts : les affinités codons-acides aminés augmentent en fonction de l’ancienneté des ARN circulaires
Des ARNs circulaires possibles chaînons de l’évolution de la traduction médiée par les ARNts : les affinités codons-acides aminés augmentent en fonction de l’ancienneté des ARN circulaires Open
Les affinites nucleotidiques des interactions non covalentes avec les acides amines produisent des associations entre les ARNm et les peptides apparentes, regulant potentiellement la traduction ribosomale. Les correlations entre les affini…
View article: Les anneaux d'ARN minimaux théoriques imitent l'évolution moléculaire avant la traduction médiée par l'ARNt : les affinités codon-acide aminé augmentent des anneaux d'ARN précoces à tardifs
Les anneaux d'ARN minimaux théoriques imitent l'évolution moléculaire avant la traduction médiée par l'ARNt : les affinités codon-acide aminé augmentent des anneaux d'ARN précoces à tardifs Open
View article: Syntenies Between Cohosted Mitochondrial, Chloroplast, and Phycodnavirus Genomes: Functional Mimicry and/or Common Ancestry?
Syntenies Between Cohosted Mitochondrial, Chloroplast, and Phycodnavirus Genomes: Functional Mimicry and/or Common Ancestry? Open
Recent analyses suggest bacterial and/or mitochondrion-like ancestry for giant viruses (Megavirales sensu latu): amoeban mitochondrial gene arrangements resemble those of their candidate homologs in megaviral genomes. This presumed …
View article: Transcripts with systematic nucleotide deletion of 1-12 nucleotide in human mitochondrion suggest potential non-canonical transcription
Transcripts with systematic nucleotide deletion of 1-12 nucleotide in human mitochondrion suggest potential non-canonical transcription Open
Raw transcriptomic data contain numerous RNA reads whose homology with template DNA doesn't match canonical transcription. Transcriptome analyses usually ignore such noncanonical RNA reads. Here, analyses search for noncanonical mitochondr…
View article: Theoretical minimal RNA rings recapitulate the order of the genetic code's codon-amino acid assignments
Theoretical minimal RNA rings recapitulate the order of the genetic code's codon-amino acid assignments Open
View article: Chimeric Translation for Mitochondrial Peptides: Regular and Expanded Codons
Chimeric Translation for Mitochondrial Peptides: Regular and Expanded Codons Open
Frameshifting protein translation occasionally results from insertion of amino acids at isolated mono- or dinucleotide-expanded codons by tRNAs with expanded anticodons. Previous analyses of two different types of human mitochondrial MS pr…
View article: Swinger RNAs in the Human Mitochondrial Transcriptome
Swinger RNAs in the Human Mitochondrial Transcriptome Open
Transcriptomes include coding and non-coding RNAs and RNA fragments with no apparent homology to parent genomes. Non-canonical transcriptions systematically transforming template DNA sequences along precise rules explain some transcripts. …
View article: Directed Mutations Recode Mitochondrial Genes: From Regular to Stopless Genetic Codes
Directed Mutations Recode Mitochondrial Genes: From Regular to Stopless Genetic Codes Open
Mitochondrial genetic codes evolve as side effects of stop codon ambiguity: suppressor tRNAs with anticodons translating stops transform genetic codes to stopless genetic codes. This produces peptides from frames other than regular ORFs, p…
View article: A New Highly Sensitive and Specific Real-Time PCR Assay Targeting the Malate Dehydrogenase Gene of Kingella kingae and Application to 201 Pediatric Clinical Specimens
A New Highly Sensitive and Specific Real-Time PCR Assay Targeting the Malate Dehydrogenase Gene of Kingella kingae and Application to 201 Pediatric Clinical Specimens Open
Kingella kingae is a significant pediatric pathogen responsible for bone and joint infections, occult bacteremia, and endocarditis in early childhood. Past efforts to detect this bacterium using culture and broad-range 16S rRNA gene PCR as…
View article: A review of sexual dimorphism of eye size in Colubroidea snakes
A review of sexual dimorphism of eye size in Colubroidea snakes Open
Eye size is interesting in snakes because in most species body length differs between the sexes, while the eye’s performance depends on its absolute size. So, does the smaller sex see less well? We hypothesized that eye sexual mensural dim…