Hessam Kakavand
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View article: Atorvastatin versus Placebo in ICU Patients with COVID-19: Ninety-day Results of the INSPIRATION-S Trial
Atorvastatin versus Placebo in ICU Patients with COVID-19: Ninety-day Results of the INSPIRATION-S Trial Open
Background In the INSPIRATION-S trial, atorvastatin versus placebo was associated with a nonsignificant 16% reduction in 30-day composite of venous/arterial thrombosis or death in intensive care unit (ICU) patients with COVID-19. Thrombo-i…
View article: Evaluating the role of intravenous pentoxifylline administration on primary percutaneous coronary intervention success rate in patients with ST-elevation myocardial infarction (PENTOS-PCI)
Evaluating the role of intravenous pentoxifylline administration on primary percutaneous coronary intervention success rate in patients with ST-elevation myocardial infarction (PENTOS-PCI) Open
View article: Atorvastatin versus placebo in patients with covid-19 in intensive care: randomized controlled trial
Atorvastatin versus placebo in patients with covid-19 in intensive care: randomized controlled trial Open
Objective To assess the effect of statin treatment versus placebo on clinical outcomes in patients with covid-19 admitted to the intensive care unit (ICU). Design INSPIRATION/INSPIRATION-S was a multicenter, randomized controlled trial wit…
View article: Investigating Lipid-Modulating Agents for Prevention or Treatment of COVID-19
Investigating Lipid-Modulating Agents for Prevention or Treatment of COVID-19 Open
View article: Use of novel antithrombotic agents for COVID‐19: Systematic summary of ongoing randomized controlled trials
Use of novel antithrombotic agents for COVID‐19: Systematic summary of ongoing randomized controlled trials Open
View article: Lipid-Modulating Agents for Prevention or Treatment of COVID-19 in Randomized Trials
Lipid-Modulating Agents for Prevention or Treatment of COVID-19 in Randomized Trials Open
Coronavirus disease 2019 (COVID-19) is associated with systemic inflammation, endothelial activation, and multi-organ manifestations. Lipid modulating agents may be useful in treating patients with COVID-19. They may inhibit viral entry by…
View article: Intermediate-Dose versus Standard-Dose Prophylactic Anticoagulation in Patients with COVID-19 Admitted to the Intensive Care Unit: 90-Day Results from the INSPIRATION Randomized Trial
Intermediate-Dose versus Standard-Dose Prophylactic Anticoagulation in Patients with COVID-19 Admitted to the Intensive Care Unit: 90-Day Results from the INSPIRATION Randomized Trial Open
Background Thrombotic complications are considered among the main extrapulmonary manifestations of coronavirus disease 2019 (COVID-19). The optimal type and duration of prophylactic antithrombotic therapy in these patients remain unknown. …
View article: Recent Randomized Trials of Antithrombotic Therapy for Patients With COVID-19
Recent Randomized Trials of Antithrombotic Therapy for Patients With COVID-19 Open
View article: Effect of Intermediate-Dose vs Standard-Dose Prophylactic Anticoagulation on Thrombotic Events, Extracorporeal Membrane Oxygenation Treatment, or Mortality Among Patients With COVID-19 Admitted to the Intensive Care Unit
Effect of Intermediate-Dose vs Standard-Dose Prophylactic Anticoagulation on Thrombotic Events, Extracorporeal Membrane Oxygenation Treatment, or Mortality Among Patients With COVID-19 Admitted to the Intensive Care Unit Open
ClinicalTrials.gov Identifier: NCT04486508.
View article: Comparing the Effects of Acceptance and Commitment Therapy and Metacognitive Therapy on Blood Pressure in Hemodialysis Patients
Comparing the Effects of Acceptance and Commitment Therapy and Metacognitive Therapy on Blood Pressure in Hemodialysis Patients Open
Background and Objectives: Dialysis patients encounter numerous psychological distress, aggravating their psycho-social problems. Currently, the third wave of psychological treatment has surpassed other treatments in solving the problems o…
View article: Antithrombotic Therapy in COVID-19: Systematic Summary of Ongoing or Completed Randomized Trials
Antithrombotic Therapy in COVID-19: Systematic Summary of Ongoing or Completed Randomized Trials Open
Endothelial injury and microvascular/macrovascular thrombosis are common pathophysiologic features of coronavirus disease-2019 (COVID-19). However, the optimal thromboprophylactic regimens remain unknown across the spectrum of illness seve…
View article: Cardiovascular Complications of COVID-19: Pharmacotherapy Perspective
Cardiovascular Complications of COVID-19: Pharmacotherapy Perspective Open
View article: Cardiovascular Considerations in Treating Patients With Coronavirus Disease 2019 (COVID-19)
Cardiovascular Considerations in Treating Patients With Coronavirus Disease 2019 (COVID-19) Open
A novel betacoronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread rapidly across the globe since December 2019. Coronavirus disease 2019 (COVID-19) has a significantly higher mortality rate than seasonal inf…