Hetao Bian
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View article: Establishing integrated chronic non-communicable disease management clinics to address China’s looming health burden
Establishing integrated chronic non-communicable disease management clinics to address China’s looming health burden Open
View article: Endovascular treatment for cerebral venous thrombosis: a multicenter study in China
Endovascular treatment for cerebral venous thrombosis: a multicenter study in China Open
View article: A multicenter single‐arm objective performance criteria trial evaluating the efficacy and safety of a dedicated venous sinus thrombectomy device for severe cerebral venous sinus thrombosis
A multicenter single‐arm objective performance criteria trial evaluating the efficacy and safety of a dedicated venous sinus thrombectomy device for severe cerebral venous sinus thrombosis Open
Aim Approximately 21% of patients with cerebral venous sinus thrombosis (CVST) are refractory to anticoagulation treatment and face poor prognosis. These patients may benefit from endovascular therapy. Although numerous studies have report…
View article: Author Correction: Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein
Author Correction: Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein Open
The original version of this Article contained an error in Fig. 4, in which the statistical significance for conditions 410C9 versus Lag3 -
View article: Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein
Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein Open
View article: Multicenter registry study of cerebral venous thrombosis in china (RETAIN‐CH): Rationale and design
Multicenter registry study of cerebral venous thrombosis in china (RETAIN‐CH): Rationale and design Open
Background and rationale Cerebral venous thrombosis (CVT) is a rare cerebrovascular disorder that mainly affects young and middle‐aged adults. Epidemiological data on the incidence, risk factors, diagnosis, treatment, and prognosis of CVT …
View article: Monocytohigh-density lipoprotein ratio has a high predictive value for the diagnosis of multiple system atrophy and the differentiation from Parkinson’s disease
Monocytohigh-density lipoprotein ratio has a high predictive value for the diagnosis of multiple system atrophy and the differentiation from Parkinson’s disease Open
Background and purpose Inflammation is closely related to the pathogenesis of multiple system atrophy (MSA). As markers of inflammation, the monocyte to high-density lipoprotein ratio (MHR), neutrophil to lymphocyte ratio (NLR), and red ce…
View article: Prevalence of stroke in China, 2013–2019: A population-based study
Prevalence of stroke in China, 2013–2019: A population-based study Open
This study was supported by grants from the National Major Public Health Service Projects.
View article: Higher serum occludin after successful reperfusion Is associated with early neurological deterioration
Higher serum occludin after successful reperfusion Is associated with early neurological deterioration Open
Aims Early neurological deterioration (END) is an important factor that affects prognosis in patients with acute ischemic stroke. We explored the relationship between serum occludin levels after successful reperfusion and END in patients t…
View article: Oridonin relieves depressive-like behaviors by inhibiting neuroinflammation and autophagy impairment in rats subjected to chronic unpredictable mild stress
Oridonin relieves depressive-like behaviors by inhibiting neuroinflammation and autophagy impairment in rats subjected to chronic unpredictable mild stress Open
Background: Major depressive disorder (MDD) is a common, chronic, and severe life-threatening disorder with increasing prevalence . Although neuroinflammation is associated with the etiology of depression, the mechanistic interplay between…
View article: Aplp1 and the Aplp1-Lag3 Complex facilitates transmission of pathologic α-synuclein
Aplp1 and the Aplp1-Lag3 Complex facilitates transmission of pathologic α-synuclein Open
Pathologic α-synuclein (α-syn) spreads from cell-to-cell, in part, through binding to the lymphocyte-activation gene 3 (Lag3). Here we report that amyloid β precursor-like protein 1 (Aplp1) forms a complex with Lag3 that facilitates the bi…
View article: Tert-Butylhydroquinone Prevents Neuroinflammation and Relieves Depression Via Regulation of NLRP3 Signaling in Mice
Tert-Butylhydroquinone Prevents Neuroinflammation and Relieves Depression Via Regulation of NLRP3 Signaling in Mice Open
View article: Dihydrolipoic acid protects against lipopolysaccharide-induced behavioral deficits and neuroinflammation via regulation of Nrf2/HO-1/NLRP3 signaling in rat
Dihydrolipoic acid protects against lipopolysaccharide-induced behavioral deficits and neuroinflammation via regulation of Nrf2/HO-1/NLRP3 signaling in rat Open
View article: Dihydrolipoic acid protects against lipopolysaccharide-induced behavioral deficits and neuroinflammation via regulation of Nrf2/HO-1/ NLRP3 signaling in rat
Dihydrolipoic acid protects against lipopolysaccharide-induced behavioral deficits and neuroinflammation via regulation of Nrf2/HO-1/ NLRP3 signaling in rat Open
Background: Recently, depression has been identified as prevalent and severe mental disorder. However, the mechanisms underlying the depression risk remain elusive. The neuroinflammation and NLRP3 inflammasome activation are known to be in…
View article: Dihydrolipoic acid protects against lipopolysaccharide-induced behavioral deficits and neuroinflammation via regulation of Nrf2/HO-1/ NLRP3 signaling in rat
Dihydrolipoic acid protects against lipopolysaccharide-induced behavioral deficits and neuroinflammation via regulation of Nrf2/HO-1/ NLRP3 signaling in rat Open
Background: Recently, depression has been identified as prevalent and severe mental disorder. However, the mechanisms underlying the depression risk remain elusive. The neuroinflammation and NLRP3 inflammasome activation are known to be in…
View article: Dihydrolipoic acid protects against lipopolysaccharide-induced behavioral deficits and neuroinflammation via regulation of Nrf2/HO-1/ NLRP3 signaling in rat
Dihydrolipoic acid protects against lipopolysaccharide-induced behavioral deficits and neuroinflammation via regulation of Nrf2/HO-1/ NLRP3 signaling in rat Open
Background: Recently, depression has been identified as prevalent and severe mental disorder. However, the mechanisms underlying the depression risk remain elusive. The neuroinflammation and NLRP3 inflammasome activation are known to be in…
View article: The arousal effect of hyperbaric oxygen through orexin/hypocretin an upregulation on ketamine/ethanol‐induced unconsciousness in male rats
The arousal effect of hyperbaric oxygen through orexin/hypocretin an upregulation on ketamine/ethanol‐induced unconsciousness in male rats Open
Approaches that facilitate the recovery from coma would have enormous impacts on patient outcomes and medical economics. Orexin‐producing neurons release orexins (also known as hypocretins) energy‐dependently to maintain arousal. Hyperbari…
View article: Prefrontoparietal dysfunction during emotion regulation in anxiety disorder: a meta-analysis of functional magnetic resonance imaging studies
Prefrontoparietal dysfunction during emotion regulation in anxiety disorder: a meta-analysis of functional magnetic resonance imaging studies Open
Impaired cognitive reappraisal in anxiety disorder may be the consequence of hypo-activation of the prefrontoparietal network, consistent with insufficient top-down control. Our findings provide robust evidence that functional impairment i…
View article: Prevalence of Stroke and Vascular Risk Factors in China: a Nationwide Community-based Study
Prevalence of Stroke and Vascular Risk Factors in China: a Nationwide Community-based Study Open
View article: Hyperbaric Oxygen Reduces Infarction Volume and Hemorrhagic Transformation Through ATP/NAD <sup>+</sup> /Sirt1 Pathway in Hyperglycemic Middle Cerebral Artery Occlusion Rats
Hyperbaric Oxygen Reduces Infarction Volume and Hemorrhagic Transformation Through ATP/NAD <sup>+</sup> /Sirt1 Pathway in Hyperglycemic Middle Cerebral Artery Occlusion Rats Open
Background and Purpose— Energy depletion is a critical factor leading to cell death and brain dysfunction after ischemic stroke. In this study, we investigated whether energy depletion is involved in hyperglycemia-induced hemorrhagic trans…