Hideaki Ono
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View article: EPCO-31. CLINICALLY APPLICABLE MOLECULAR GROUPING OF INTRACRANIAL MENINGIOMAS BASED ON HIGH-RISK COPY NUMBER ALTERATIONS AND <i>NF2</i> /22Q STATUS
EPCO-31. CLINICALLY APPLICABLE MOLECULAR GROUPING OF INTRACRANIAL MENINGIOMAS BASED ON HIGH-RISK COPY NUMBER ALTERATIONS AND <i>NF2</i> /22Q STATUS Open
BACKGROUND The 2021 WHO classification of meningiomas incorporated molecular markers such as CDKN2A/B homozygous deletion and TERT promoter (pTERT) mutations as diagnostic criteria for grade 3 tumors. Although large-scale multi-omics studi…
View article: A multicenter phase II study of eribulin for BRAF V600E mutant metastatic colorectal cancer: the BRAVERY study (EPOC1701)
A multicenter phase II study of eribulin for BRAF V600E mutant metastatic colorectal cancer: the BRAVERY study (EPOC1701) Open
View article: Two molecular subtypes of skull base meningiomas with extracranial extension
Two molecular subtypes of skull base meningiomas with extracranial extension Open
View article: Integrated molecular and detailed anatomical profiling identifies a prognostically adverse subtype of posterior fossa meningiomas: high-risk copy number alterations are associated with midline predilection and predict poor prognosis
Integrated molecular and detailed anatomical profiling identifies a prognostically adverse subtype of posterior fossa meningiomas: high-risk copy number alterations are associated with midline predilection and predict poor prognosis Open
View article: Quantitative evaluation of the vasodilatory effect of clazosentan in preventing cerebral vasospasm after subarachnoid hemorrhage
Quantitative evaluation of the vasodilatory effect of clazosentan in preventing cerebral vasospasm after subarachnoid hemorrhage Open
Background and Purpose Although many studies have reported the efficacy of clazosentan in preventing delayed cerebral ischemia associated with cerebral vasospasm after aneurysmal subarachnoid hemorrhage (aSAH), recent studies have shown th…
View article: Outcomes and Complications of Endovascular Treatment in Patients with Moyamoya Disease: A Systematic Review
Outcomes and Complications of Endovascular Treatment in Patients with Moyamoya Disease: A Systematic Review Open
For the patients with MMD, EVT of distal aneurysms would likely be unsuccessful because of the access difficulties. Furthermore, EVT for intracranial arterial stenosis often results in unsatisfactory treatment and has limited indications o…
View article: Video-Based Propagation of Tacit Knowledge During Coil Embolization of Intracranial Aneurysms
Video-Based Propagation of Tacit Knowledge During Coil Embolization of Intracranial Aneurysms Open
Our hybrid and wearable recording and editing methods facilitated the propagation of tacit knowledge of coil embolization and enhanced surgical education by enabling more efficient learning of technical tips.
View article: Current molecular understanding of central nervous system schwannomas
Current molecular understanding of central nervous system schwannomas Open
A deeper exploration of these molecular findings could clarify the mechanisms of schwannoma tumorigenesis and progression, ultimately guiding the development of new therapeutic targets. This review offers a comprehensive overview of the cu…
View article: Contribution of watertight dural closure to prevention of postoperative cerebrospinal fluid leakage in endoscopic transnasal surgery for intradural lesions
Contribution of watertight dural closure to prevention of postoperative cerebrospinal fluid leakage in endoscopic transnasal surgery for intradural lesions Open
OBJECTIVE The goal of this study was to evaluate the efficacy of watertight dural closure (WTDC) in preventing postoperative CSF leakage during extended endoscopic transnasal surgery (ETS) for skull base tumors, while preserving sinonasal …
View article: RNF213 p.Arg4810Lys Variant Is Associated with Higher Stenosis Progression in Asymptomatic Intracranial Artery Stenosis
RNF213 p.Arg4810Lys Variant Is Associated with Higher Stenosis Progression in Asymptomatic Intracranial Artery Stenosis Open
View article: N-butyl Cyanoacrylate Use in Various Neuroendovascular Diseases
N-butyl Cyanoacrylate Use in Various Neuroendovascular Diseases Open
This review discusses the use of N-butyl cyanoacrylate (NBCA) in various neuroendovascular treatments. Despite the increase in the ONYX, NBCA continues to have significant usage. It is particularly useful for the treatment of arteriovenous…
View article: Acute Hemorrhagic-Onset Atypical Meningioma: A Report of Two Cases with Emergent Resection Achieving Mid-Term Tumor Control and Neurological Preservation
Acute Hemorrhagic-Onset Atypical Meningioma: A Report of Two Cases with Emergent Resection Achieving Mid-Term Tumor Control and Neurological Preservation Open
The majority of meningiomas are slow-growing benign tumors that can potentially be highly vascularized; however, acute hemorrhagic onset is rare. Herein, we describe two patients who presented with disturbance of consciousness and severe h…
View article: Association of Genetic Variants with Postoperative Donor Artery Development in Moyamoya Disease: RNF213 and Other Moyamoya Angiopathy-Related Gene Analysis
Association of Genetic Variants with Postoperative Donor Artery Development in Moyamoya Disease: RNF213 and Other Moyamoya Angiopathy-Related Gene Analysis Open
View article: Open Surgery First Strategy for Ruptured Cerebral Aneurysms in the Current Neurosurgical Circumstance
Open Surgery First Strategy for Ruptured Cerebral Aneurysms in the Current Neurosurgical Circumstance Open
View article: Usefulness of Digital Illustration Creation for Neurosurgery
Usefulness of Digital Illustration Creation for Neurosurgery Open
View article: Orbital Arteriovenous Fistula Causing Only Visual Impairment due to Compression of the Optic Nerve by the Dilated Superior Ophthalmic Vein
Orbital Arteriovenous Fistula Causing Only Visual Impairment due to Compression of the Optic Nerve by the Dilated Superior Ophthalmic Vein Open
Orbital arteriovenous fistula (AVF) is a rare disease, and its standard therapeutic strategy has not been established. A 70-year-old male consulted an ophthalmologist due to a visual field defect in his left eye. Neurological findings show…
View article: RNF213 p.Arg4810Lys Wild Type is Associated with De Novo Hemorrhage in Asymptomatic Hemispheres with Moyamoya Disease
RNF213 p.Arg4810Lys Wild Type is Associated with De Novo Hemorrhage in Asymptomatic Hemispheres with Moyamoya Disease Open
View article: Comparative Study of a Membranous Labyrinth and Osseous Labyrinth Model
Comparative Study of a Membranous Labyrinth and Osseous Labyrinth Model Open
A 1.5-time-scale mockup of the head with a built-in 10-time-scale mockup of the osseous semicircular canals was made based on the CT image of the healthy human temporal bone. When we use this model for the original canalith repositioning p…
View article: 230 A STRESS-RELATED NEUROPEPTIDE CORTICOTROPIN-RELEASING FACTOR INDUCES FACILITATION OF THE RAT MICTURITION THROUGH BRAIN GLUTAMATERGIC RECEPTORS
230 A STRESS-RELATED NEUROPEPTIDE CORTICOTROPIN-RELEASING FACTOR INDUCES FACILITATION OF THE RAT MICTURITION THROUGH BRAIN GLUTAMATERGIC RECEPTORS Open
View article: STA-A3 Bypass Using Radial Artery Graft for Progressive Cerebral Infarction of Bilateral ACA Region after STA-MCA Bypass Surgery for Moyamoya Disease
STA-A3 Bypass Using Radial Artery Graft for Progressive Cerebral Infarction of Bilateral ACA Region after STA-MCA Bypass Surgery for Moyamoya Disease Open
Direct revascularization surgery, such as superficial temporal artery (STA)-middle cerebral artery (MCA) bypass, is effective in preventing ischemia and hemorrhage for moyamoya disease. On the other hand, when ischemia of the anterior cere…
View article: Centrally administered corticotropin-releasing factor facilitates the rat micturition reflex via brain glutamatergic receptors
Centrally administered corticotropin-releasing factor facilitates the rat micturition reflex via brain glutamatergic receptors Open
Roles of brain corticotropin-releasing factor (CRF), a representative stress-related neuropeptide, on micturition reflex are controversial, both suppressive and facilitatory roles are reported. In this study, we examined effects of intrace…
View article: Basic Techniques for the Clipping of Middle Cerebral Aneurysms: Gaining Expertise with Limited Surgical Experience
Basic Techniques for the Clipping of Middle Cerebral Aneurysms: Gaining Expertise with Limited Surgical Experience Open
中大脳動脈瘤クリッピング術は,脳動脈瘤クリッピング術の基本として位置づけられる.当院では若手術者が限られた症例数の中で手術手技を習得できるように,手術の細部にいたるまでコンセプトを明確にし統一徹底している.sylvian fissureの展開に関しては,安全で精確なretractionとsharp dissectionを用いて必要十分な広範囲の展開を,動脈瘤へのアプローチに関しては動脈瘤非癒着側からの剝離手順を,それぞれ徹底している.今回これらのコンセプトを紹介するとともに…
View article: Mechanisms of hydrogen sulfide-induced protective effect on rat bladder dysfunction induced by cyclophosphamide
Mechanisms of hydrogen sulfide-induced protective effect on rat bladder dysfunction induced by cyclophosphamide Open
We have reported protective effect of NaHS [hydrogen sulfide (H2S) donor] on cyclophosphamide (CYP)-induced rat bladder dysfunction by improving CYP-induced shortening of intercontraction intervals (ICI) and increases in non-voiding contra…
View article: Correction to: RNF213 p.Arg4810Lys Heterozygosity in Moyamoya Disease Indicates Early Onset and Bilateral Cerebrovascular Events
Correction to: RNF213 p.Arg4810Lys Heterozygosity in Moyamoya Disease Indicates Early Onset and Bilateral Cerebrovascular Events Open
View article: Extradural Middle Fossa and Transcavernous Approach for Resection of Trigeminal Neurinoma at Lateral Cavernous Sinus
Extradural Middle Fossa and Transcavernous Approach for Resection of Trigeminal Neurinoma at Lateral Cavernous Sinus Open
We present a 52-year-old male case of right trigeminal neurinoma at lateral cavernous sinus. The tumor was 40 mm in maximum diameter, obviously compressed temporal lobe and encased internal carotid artery. Extradural middle fossa and trans…
View article: Giant Fusiform and Dolichoectatic Aneurysms of the Basilar Trunk and Vertebrobasilar Junction—Clinicopathological and Surgical Outcome
Giant Fusiform and Dolichoectatic Aneurysms of the Basilar Trunk and Vertebrobasilar Junction—Clinicopathological and Surgical Outcome Open
Nakatomi, Hirofumi MD, PhD; Kiyofuji, Satoshi MD; Ono, Hideaki MD, PhD; Tanaka, Minoru MD, PhD; Kamiyama, Hiroyasu MD; Takizawa, Katsumi MD; Imai, Hideaki MD, PhD; Saito, Nobuhito MD, PhD; Shiokawa, Yoshiaki MD, PhD; Morita, Akio MD, PhD; …
View article: MP08-01 BRAIN α7 NICOTINIC ACETYLCHOLINE RECEPTORS ARE INVOLVED IN SUPPRESSION OF THE RAT MICTURITION REFLEX VIA BRAIN GABA RECEPTORS
MP08-01 BRAIN α7 NICOTINIC ACETYLCHOLINE RECEPTORS ARE INVOLVED IN SUPPRESSION OF THE RAT MICTURITION REFLEX VIA BRAIN GABA RECEPTORS Open
You have accessJournal of UrologyBladder & Urethra: Anatomy, Physiology & Pharmacology (MP08)1 Sep 2021MP08-01 BRAIN α7 NICOTINIC ACETYLCHOLINE RECEPTORS ARE INVOLVED IN SUPPRESSION OF THE RAT MICTURITION REFLEX VIA BRAIN GABA RECEPTORS Ta…
View article: Differences in Clinical Features among Different Onset Patterns in Moyamoya Disease
Differences in Clinical Features among Different Onset Patterns in Moyamoya Disease Open
Moyamoya disease is characterized by severe stenosis at the ends of the bilateral internal carotid arteries and the development of collateral circulation. The disease is very diverse in terms of age at onset, onset patterns, radiological f…
View article: T11/T12 ossification of the yellow ligament contributing to thoracic myelopathy in patient with posterior fossa arachnoid cyst and acquired incidental Chiari I malformation/syrinx
T11/T12 ossification of the yellow ligament contributing to thoracic myelopathy in patient with posterior fossa arachnoid cyst and acquired incidental Chiari I malformation/syrinx Open
Background: Thoracic ossification of the yellow ligament (OYL) may contribute to myelopathy. In the case presented, the patient additionally had a chronic posterior fossa arachnoid cyst with an acquired Chiari I malformation and cervicotho…
View article: Stimulation of brain α7-nicotinic acetylcholine receptors suppresses the rat micturition through brain GABAergic receptors
Stimulation of brain α7-nicotinic acetylcholine receptors suppresses the rat micturition through brain GABAergic receptors Open