Hideki Igarashi
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View article: P-005 Improved sperm retrieval rates (SRR) and ejaculated sperm recovery after varicocelectomy in non-obstructive azoospermia (NOA): Implications for assisted reproductive technology (ART) outcomes
P-005 Improved sperm retrieval rates (SRR) and ejaculated sperm recovery after varicocelectomy in non-obstructive azoospermia (NOA): Implications for assisted reproductive technology (ART) outcomes Open
Study question How does varicocelectomy impact ejaculated sperm recovery, SRR of microdissection testicular sperm extraction (mTESE), ART outcomes, and the proportion of idiopathic NOA couples achieving pregnancy? Summary answer Varicocele…
View article: O-102 The utility of human two plus one small pronucleated zygotes (2.1pn) based on clinical outcomes and novel ploidy analysis
O-102 The utility of human two plus one small pronucleated zygotes (2.1pn) based on clinical outcomes and novel ploidy analysis Open
Study question Are human embryos arising from two plus one small pronucleated zygotes, referred to as 2.1 pronuclei (PN), clinically useful? Summary answer Five healthy babies were born from vitrified-warmed 2.1PN blastocysts. In ploidy an…
View article: Clinical Outcomes of Frozen-Thawed Single Blastocyst Transfers in Relation to Blastocyst Diameter and Timing of Cryopreservation
Clinical Outcomes of Frozen-Thawed Single Blastocyst Transfers in Relation to Blastocyst Diameter and Timing of Cryopreservation Open
Background: It is important to select blastocysts based on their likelihood of leading to pregnancy. The purpose of this study was to focus on expansion time and blastocyst diameter as simple factors to assess blastocysts relative to clini…
View article: The utility of human two plus one small pronucleated zygotes (2.1PN) based on clinical outcomes and the focused ploidy analysis
The utility of human two plus one small pronucleated zygotes (2.1PN) based on clinical outcomes and the focused ploidy analysis Open
Purpose Are human embryos arising from two plus one small pronucleated zygotes, called 2.1 pronuclei (PN), clinically useful? Methods In a retrospective embryo cohort study and prospective experimental study, a total of 287 cycles in which…
View article: Micromapping testicular sperm extraction: A new technique for microscopic testicular sperm extraction in nonobstructive azoospermia
Micromapping testicular sperm extraction: A new technique for microscopic testicular sperm extraction in nonobstructive azoospermia Open
Purpose In microscopic testicular sperm extraction (mTESE) for nonobstructive azoospermia (NOA), sperm can be recovered relatively easily in some cases, and mTESE may be retrospectively considered excessive. However, mTESE is routinely per…
View article: #146 : Low-Lactate Culture Medium Increases the Percentage of Usable Blastocysts from Advanced Maternal Age Patients: A Sibling-Oocyte, Monocentric Study
#146 : Low-Lactate Culture Medium Increases the Percentage of Usable Blastocysts from Advanced Maternal Age Patients: A Sibling-Oocyte, Monocentric Study Open
Background and Aims: Excess lactate in culture medium accumulates may adversely affect the embryo as metabolic stress. The purpose of this study is to investigate whether culture media with a low-lactate concentration have an effect on emb…
View article: P-089 effect of testis tissue retrieval on “Micro Mapping Testicular Extraction” (MMTE): comparison with microscopic testicular sperm extraction (Micro TESE) in non-obstructive azoospermia (NOA)
P-089 effect of testis tissue retrieval on “Micro Mapping Testicular Extraction” (MMTE): comparison with microscopic testicular sperm extraction (Micro TESE) in non-obstructive azoospermia (NOA) Open
Study question Is a new sperm retrieval method, Micro Mapping Testicular Extraction (MMTE) comparable to that of Microscopic testicular sperm extraction (Micro TESE)? Summary answer MMTE is comparable to that of Micro TESE regarding sperm …
View article: Additional Estrogen Administration to Avoid Poor Outcomes Associated with a Thin Endometrium in Frozen Embryo Transfer
Additional Estrogen Administration to Avoid Poor Outcomes Associated with a Thin Endometrium in Frozen Embryo Transfer Open
Background: During hormone replacement therapy (HRT) to optimize endometrial growth for thawed-frozen embryo transfer (FET), patients normally undergo estrogen administration for 14 days (day 14 group). However, if optimal endometrial thic…
View article: Chlormadinone acetate in progestin‐primed ovarian stimulation does not negatively affect clinical results
Chlormadinone acetate in progestin‐primed ovarian stimulation does not negatively affect clinical results Open
Purpose To investigate whether progestin‐primed ovarian stimulation (PPOS) with chlormadinone acetate (CMA) adversely affects clinical results and neonatal outcomes, or causes congenital deformities. Methods This retrospective study was co…
View article: Clinical outcomes of personalized blastocyst embryo transfer after endometrial receptivity analysis: A multicenter, retrospective cohort study
Clinical outcomes of personalized blastocyst embryo transfer after endometrial receptivity analysis: A multicenter, retrospective cohort study Open
Purpose To evaluate clinical outcomes after endometrial receptivity analysis (ERA). Methods This was a multicenter, retrospective cohort study involving 861 women who underwent ERA testing at certified fertility clinics in Japan, and who r…
View article: Obstetrical and Neonatal Outcomes of 3,028 Singletons Born After Advanced ART Techniques: Ejaculated Sperm Intracytoplasmic Sperm Injection, Artificial Oocyte Activation, in Vitro Maturation and Testicular Sperm Extraction
Obstetrical and Neonatal Outcomes of 3,028 Singletons Born After Advanced ART Techniques: Ejaculated Sperm Intracytoplasmic Sperm Injection, Artificial Oocyte Activation, in Vitro Maturation and Testicular Sperm Extraction Open
Background: To evaluate obstetrical and neonatal outcomes of singletons conceived after advanced assisted reproductive technology (ART) techniques: conventional IVF pregnancies (C-IVF), ejaculated sperm intracytoplasmic sperm injection (IC…
View article: Evaluation of Pregnancy Outcomes of Vitrified-Warmed Blastocyst Transfer before and after Endometrial Receptivity Analysis in Identical Patients with Recurrent Implantation Failure
Evaluation of Pregnancy Outcomes of Vitrified-Warmed Blastocyst Transfer before and after Endometrial Receptivity Analysis in Identical Patients with Recurrent Implantation Failure Open
Background: The clinical value of personalized embryo transfer (pET) guided by the endometrial receptivity analysis (ERA) tests for recurrent implantation failure (RIF) cases is still unclear. The aim of this study is to clarify the effica…
View article: Two Successful Deliveries after 6 and 13 Years from 10 Oocytes Vitrified for Fertility Preservation in a Then 20-Year-Old Patient with PH-Positive Acute Lymphoid Leukemia
Two Successful Deliveries after 6 and 13 Years from 10 Oocytes Vitrified for Fertility Preservation in a Then 20-Year-Old Patient with PH-Positive Acute Lymphoid Leukemia Open
Oocyte vitrification is one of the methods for preserving fertility of cancer patients. In 2013, we reported a successful live birth using cryopreserved oocytes from a patient who contracted Ph-positive acute lymphoid leukemia at the retri…
View article: RELUGOLIX, A NOVEL ORALLY ACTIVE GnRH ANTAGONIST IS EFFECTIVE IN IVF PROTOCOL
RELUGOLIX, A NOVEL ORALLY ACTIVE GnRH ANTAGONIST IS EFFECTIVE IN IVF PROTOCOL Open
View article: A case of peritoneal pregnancy on the pouch of Douglas: Laparoscopic removal of the gestational sac using a reusable surgical probe for the rectum
A case of peritoneal pregnancy on the pouch of Douglas: Laparoscopic removal of the gestational sac using a reusable surgical probe for the rectum Open
Peritoneal pregnancy is relatively rare and accounts for approximately 1% of all ectopic pregnancies. Accurately diagnosing peritoneal pregnancy before surgery is difficult; thus, gynecologists may encounter the disease accidentally.Many s…
View article: Y chromosome microdeletion screening using a new molecular diagnostic method in 1030 Japanese males with infertility
Y chromosome microdeletion screening using a new molecular diagnostic method in 1030 Japanese males with infertility Open
The azoospermia factor (AZF) region is important for spermatogenesis, and deletions within these regions are a common cause of oligozoospermia and azoospermia. Although several studies have reported this cause, the present research, to the…
View article: Impact of meiotic spindle imaging on fertilization, embryo development, clinical outcome and morphokinetic parameters: an analysis of 415 in-vivo matured and 317 in-vitro matured human oocyte siblings
Impact of meiotic spindle imaging on fertilization, embryo development, clinical outcome and morphokinetic parameters: an analysis of 415 in-vivo matured and 317 in-vitro matured human oocyte siblings Open
View article: Effectiveness and optimal dose of chlormadinone acetate (CMA) as progestin-primed ovarian stimulation
Effectiveness and optimal dose of chlormadinone acetate (CMA) as progestin-primed ovarian stimulation Open
View article: Effects of melatonin and resveratrol on embryo development and clinical outcomes in poor-prognosis IVF patients
Effects of melatonin and resveratrol on embryo development and clinical outcomes in poor-prognosis IVF patients Open
View article: Long‐term clinical outcomes of testicular sperm extraction and intracytoplasmic sperm injection for infertile men
Long‐term clinical outcomes of testicular sperm extraction and intracytoplasmic sperm injection for infertile men Open
Purpose To find the best methods to achieve the highest pregnancy and birth rates for couples needing testicular sperm extraction ( TESE )‐intracytoplasmic sperm injection ( ICSI ). Methods Retrospectively studied were 801 patients with ma…
View article: A transportation network for human ovarian tissue is indispensable to success for fertility preservation
A transportation network for human ovarian tissue is indispensable to success for fertility preservation Open
View article: Efficacy of the endometrial receptivity array for repeated implantation failure in Japan: A retrospective, two‐centers study
Efficacy of the endometrial receptivity array for repeated implantation failure in Japan: A retrospective, two‐centers study Open
Aim This study aimed to assess the efficacy of the endometrial receptivity array ( ERA ) as a diagnostic tool and the impact of personalized embryo transfer ( pET ) for the treatment of patients with recurrent implantation failure ( RIF ) …
View article: Development of a new clinically applicable device for embryo evaluation which measures embryo oxygen consumption
Development of a new clinically applicable device for embryo evaluation which measures embryo oxygen consumption Open
Not applicable.
View article: Does in vitro maturation (IVM) have an impact on morphokinetic parameters in comparison with IVF?
Does in vitro maturation (IVM) have an impact on morphokinetic parameters in comparison with IVF? Open
View article: Predictive factors for oocyte retrieval failure in controlled ovarian hyperstimulation protocols: a retrospective observational cohort study
Predictive factors for oocyte retrieval failure in controlled ovarian hyperstimulation protocols: a retrospective observational cohort study Open
Our results suggest that in cycles with GnRH antagonist protocol, the levels of estradiol and LH on the day of hCG injection might be predictive factors for oocyte retrieval failure. This relationship may provide useful information to both…
View article: Oocyte aging underlies female reproductive aging: biological mechanisms and therapeutic strategies
Oocyte aging underlies female reproductive aging: biological mechanisms and therapeutic strategies Open
In recent years, postponement of marriage and childbearing in women of reproductive age has led to an increase in the incidence of age‐related infertility. The reproductive aging process in women is assumed to occur due to a decrease in bo…