Hideya Iwaki
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View article: Differences in Anti-αvβ6 Integrin Antibody Expression between U.S. and Japanese Cohorts in Inflammatory Bowel Disease
Differences in Anti-αvβ6 Integrin Antibody Expression between U.S. and Japanese Cohorts in Inflammatory Bowel Disease Open
Background Inflammatory bowel diseases (IBDs), including ulcerative colitis (UC) and Crohn’s disease (CD), have complex pathologies requiring precise diagnostic tools. We evaluated the clinical utility of anti-integrin αvβ6 antibodies in d…
View article: Evaluation of Organoid‐Derived Exosomal <scp>microRNA</scp> as Liquid Biopsy for Colorectal Cancer: A Multicenter Cross‐Sectional Study
Evaluation of Organoid‐Derived Exosomal <span>microRNA</span> as Liquid Biopsy for Colorectal Cancer: A Multicenter Cross‐Sectional Study Open
Exosomal microRNAs (miRNAs) are candidates for liquid biopsies. Organoid culture systems enable long‐term expansion of the colon epithelium. This study evaluated exosomal miRNAs from colorectal cancer organoids for liquid biopsy. Organoids…
View article: Autoantibodies against endothelial protein C receptor and integrin αvβ6 predict the development of ulcerative colitis
Autoantibodies against endothelial protein C receptor and integrin αvβ6 predict the development of ulcerative colitis Open
Background A method for predicting ulcerative colitis (UC) onset has not been established. Serum autoantibodies have been suggested as potential predictive biomarkers for UC onset. We aimed to validate the risks associated with serological…
View article: Evolving Trends in Pediatric Inflammatory Bowel Disease Management in Japan: A Decade of Nationwide Data
Evolving Trends in Pediatric Inflammatory Bowel Disease Management in Japan: A Decade of Nationwide Data Open
Aims This study aimed to investigate the trends in pediatric inflammatory bowel diseases (IBD) management in Japan over the past decade. Methods We retrospectively analyzed data from Japan's nationwide database from 2012 to 2022. Patients …
View article: Endoscopic radial incision and cutting using balloon-assisted enteroscopy for small intestinal stenosis related to Crohn’s disease: a pilot study
Endoscopic radial incision and cutting using balloon-assisted enteroscopy for small intestinal stenosis related to Crohn’s disease: a pilot study Open
Background/Aims: Radial incision and cutting (RIC) is an alternative dilation method for stenosis of the lower gastrointestinal tract. However, its safety and efficacy for the small intestine requiring balloon-assisted enteroscopy (BAE) re…
View article: Author Correction: PNPO–PLP axis senses prolonged hypoxia in macrophages by regulating lysosomal activity
Author Correction: PNPO–PLP axis senses prolonged hypoxia in macrophages by regulating lysosomal activity Open
View article: Safety and effectiveness of additional triamcinolone acetonide with endoscopic radial incision and cutting for benign stenosis of the lower gastrointestinal tract: A pilot study
Safety and effectiveness of additional triamcinolone acetonide with endoscopic radial incision and cutting for benign stenosis of the lower gastrointestinal tract: A pilot study Open
Objectives Radial incision and cutting (RIC) is being investigated as an alternative endoscopic dilation method for lower intestinal tract stenosis, providing a high technical success rate and improving subjective symptoms. However, severa…
View article: PNPO–PLP axis senses prolonged hypoxia in macrophages by regulating lysosomal activity
PNPO–PLP axis senses prolonged hypoxia in macrophages by regulating lysosomal activity Open