Hillard Weinstock
YOU?
Author Swipe
Reported Neurologic, Ocular, and Otic Manifestations Among Syphilis Cases—16 States, 2019 Open
Background Syphilis can cause neurologic, ocular, or otic manifestations, possibly resulting in permanent disability or death. In 2018, the Centers for Disease Control and Prevention began collecting syphilis clinical manifestation data vi…
View article: Surveillance for Disseminated Gonococcal Infections, Active Bacterial Core Surveillance (ABCs)—United States, 2015–2019
Surveillance for Disseminated Gonococcal Infections, Active Bacterial Core Surveillance (ABCs)—United States, 2015–2019 Open
Background Disseminated gonococcal infections (DGIs) are thought to be uncommon; surveillance is limited, and case reports are analyzed retrospectively or in case clusters. We describe the population-level burden of culture-confirmed DGIs …
Antimicrobial Susceptibility of Urogenital and Extragenital Neisseria gonorrhoeae Isolates Among Men Who Have Sex With Men: Strengthening the US Response to Resistant Gonorrhea and Enhanced Gonococcal Isolate Surveillance Project, 2018 to 2019. Open
Based on data collected from multijurisdictional sentinel surveillance projects, antimicrobial susceptibility patterns of Neisseria gonorrhoeae isolates may differ among MSM at extragenital sites, particularly at the pharynx. Continued inv…
1359. Reported Neurologic, Ocular, and Otic Manifestations among Syphilis Cases — 16 States, 2019 Open
Background Syphilis can cause neurologic, ocular, or otic manifestations at any stage, possibly resulting in permanent disability or even death. In 2018, CDC began collecting clinical manifestation data for syphilis cases reported through …
164. Antimicrobial Susceptibility of Urogenital and Extragenital <i>Neisseria gonorrhoeae</i> Isolates Among Men Who Have Sex with Men – SURRG and eGISP, 2018–2019 Open
Background Extragenital gonococcal infections are common among men who have sex with men (MSM); however, data comparing antimicrobial susceptibilities of urogenital and extragenital Neisseria gonorrhoeae isolates are limited. We investigat…
Impact of the COVID-19 Pandemic on Centers for Disease Control and Prevention–Funded Sexually Transmitted Disease Programs Open
The COVID-19 pandemic impacted sexually transmitted disease (STD) services. Of 59 US-funded STD programs, 91% reported a great deal to moderate impact from staff reassignment in April 2020, with 28% of respondents reporting permanent reass…
View article: Congenital Syphilis Diagnosed Beyond the Neonatal Period in the United States: 2014–2018
Congenital Syphilis Diagnosed Beyond the Neonatal Period in the United States: 2014–2018 Open
BACKGROUND AND OBJECTIVES During 2014–2018, reported congenital syphilis (CS) cases in the United States increased 183%, from 462 to 1306 cases. We reviewed infants diagnosed with CS beyond the neonatal period (>28 days) during this time. …
Trends in Nationally Notifiable Sexually Transmitted Disease Case Reports During the US COVID-19 Pandemic, January to December 2020 Open
Background To describe changes in reported sexually transmitted diseases (STDs) during the US coronavirus disease 2019 pandemic, we compared the weekly number of reported nationally notifiable STDs in 2020 to 2019. Methods We reviewed case…
O09.3 Gonococcal pharyngeal susceptibility to ceftriaxone, cefixime and azithromycin among men and women in eGISP, 2018 – 2020 Open
Background Most gonorrhea treatment failures on ceftriaxone-based regimens, the foundation of current treatment recommendations, have been associated with pharyngeal infections; however, antimicrobial susceptibility data for pharyngeal inf…
Genomic Analysis of the Predominant Strains and Antimicrobial Resistance Determinants Within 1479 Neisseria gonorrhoeae Isolates From the US Gonococcal Isolate Surveillance Project in 2018 Open
Background The prevalence of Neisseria gonorrhoeae (GC) isolates with elevated minimum inhibitory concentrations to various antibiotics continues to rise in the United States and globally. Genomic analysis provides a powerful tool for surv…
View article: Prevalence of Urogenital Mycoplasma genitalium Infection, United States, 2017 to 2018
Prevalence of Urogenital Mycoplasma genitalium Infection, United States, 2017 to 2018 Open
During the 2017–2018 National Health and Nutrition Examination Survey, urine samples from participants aged 14 to 59 years were tested for Mycoplasma genitalium infection. Overall prevalence was 1.7% (95% confidence interval [CI], 1.1%–2.7…
Genital Mycoplasma, Shigellosis, Zika, Pubic Lice, and Other Sexually Transmitted Infections: Neither Gone Nor Forgotten Open
Most estimates of the combined burden and cost of sexually transmitted infections (STIs) in the United States have focused on 8 common STIs with established national surveillance strategies (chlamydia, gonorrhea, syphilis, trichomoniasis, …
Sexually Transmitted Infections Among US Women and Men: Prevalence and Incidence Estimates, 2018 Open
Background The most recent estimates of the number of prevalent and incident sexually transmitted infections (STIs) in the United States were for 2008. We provide updated estimates for 2018 using new methods. Methods We estimated the total…
View article: Update to CDC's Treatment Guidelines for Gonococcal Infection, 2020
Update to CDC's Treatment Guidelines for Gonococcal Infection, 2020 Open
Sexually transmitted infections (STIs) caused by the bacteria Neisseria gonorrhoeae (gonococcal infections) have increased 63% since 2014 and are a cause of sequelae including pelvic inflammatory disease, ectopic pregnancy, and infertility…
Collection of Gender Identity in National Case Notifications of Chlamydia, Gonorrhea, and Primary and Secondary Syphilis, 2018 Open
In 2018, 21 (41%) jurisdictions had begun reporting gender identity for sexually transmitted disease case notifications sent to the Centers for Disease Control and Prevention. Among jurisdictions with ≥70% of cases with reported gender ide…
View article: Azithromycin susceptibility of Neisseria gonorrhoeae in the USA in 2017: a genomic analysis of surveillance data
Azithromycin susceptibility of Neisseria gonorrhoeae in the USA in 2017: a genomic analysis of surveillance data Open
US Centers for Disease Control and Prevention (CDC), CDC Combating Antibiotic Resistant Bacteria initiative, Oak Ridge Institute for Science Education, US Department of Energy/CDC/Emory University, National Institutes of Health, and Biomed…
View article: Missed Opportunities for Prevention of Congenital Syphilis — United States, 2018
Missed Opportunities for Prevention of Congenital Syphilis — United States, 2018 Open
Congenital syphilis is an infection with Treponema pallidum in an infant or fetus, acquired during pregnancy from a mother with untreated or inadequately treated syphilis. Congenital syphilis can cause miscarriage, stillbirth, or early inf…
View article: Expanding U.S. Laboratory Capacity for Neisseria gonorrhoeae Antimicrobial Susceptibility Testing and Whole-Genome Sequencing through the CDC's Antibiotic Resistance Laboratory Network
Expanding U.S. Laboratory Capacity for Neisseria gonorrhoeae Antimicrobial Susceptibility Testing and Whole-Genome Sequencing through the CDC's Antibiotic Resistance Laboratory Network Open
U.S. gonorrhea rates are rising, and antibiotic-resistant Neisseria gonorrhoeae (AR-Ng) is an urgent public health threat. Since implementation of nucleic acid amplification tests for N. gonorrhoeae identification, the capacity for culturi…
434. Concurrent Gonococcal Infections with Differing Susceptibility Results from the Enhanced Gonococcal Isolate Surveillance Project (eGISP) Open
Background Concurrent gonococcal infections could impact treatment success in cases of anatomic site-specific strains with different antimicrobial susceptibilities; however, little is known about same-patient differences in susceptibility …
P528 Rates of primary and secondary syphilis among men who have sex with men by HIV status – 24 states, 2011–2015 Open
Background During 2011–2015, approximately half (48% to 53%) of reported primary and secondary (P&S) syphilis cases occurred among men who have sex with men (MSM) with diagnosed HIV. However, comparing rates of reported P&S syphilis by HIV…
P634 Surveillance for disseminated gonococcal infections, active bacterial core surveillance (ABCs) – united states, 2015–2018 Open
Background Disseminated gonococcal infections (DGI) are uncommon; occurring in an estimated 0.5–3% of Neisseria gonorrhoeae (GC) cases. DGI surveillance is limited and case reports are often analyzed retrospectively or in case clusters. We…
Rationale for a <i>Neisseria gonorrhoeae</i> Susceptible–only Interpretive Breakpoint for Azithromycin Open
Background Azithromycin (AZI) is recommended with ceftriaxone (CRO) for treatment of uncomplicated gonococcal urethritis and cervicitis in the United States, and an AZI-susceptibility breakpoint is needed. Neither the Food and Drug Adminis…
View article: Evidence of Recent Genomic Evolution in Gonococcal Strains With Decreased Susceptibility to Cephalosporins or Azithromycin in the United States, 2014–2016
Evidence of Recent Genomic Evolution in Gonococcal Strains With Decreased Susceptibility to Cephalosporins or Azithromycin in the United States, 2014–2016 Open
Whole-genome sequencing methods can enhance monitoring of antimicrobial resistant gonococcal strains by identifying gonococcal populations containing mutations of concern. These methods could inform the development of point-of-care diagnos…
Increased Methamphetamine, Injection Drug, and Heroin Use Among Women and Heterosexual Men with Primary and Secondary Syphilis — United States, 2013–2017 Open
During 2013-2017, the national annual rate of reported primary and secondary (P&S) syphilis cases in the United States increased 72.7%, from 5.5 to 9.5 cases per 100,000 population (1). The highest rates of P&S syphilis are seen among gay,…
1167. Trends in Multi-Drug-Resistant Gonorrhea, Gonococcal Isolate Surveillance Project, United States, 1987–2016 Open
Background Neisseria gonorrhoeae’s ability to develop resistance to antibiotics used for treatment and a limited development of new therapies have made this organism one of three urgent threat pathogens in the United States. We provide the…
Adherence to CDC Recommendations for the Treatment of Uncomplicated Gonorrhea — STD Surveillance Network, United States, 2016 Open
Gonorrhea, the sexually transmitted disease (STD) caused by Neisseria gonorrhoeae, is the second most common notifiable disease in the United States after chlamydia; 468,514 cases were reported to state and local health departments in 2016…
Reported Primary and Secondary Syphilis Cases in the United States: Implications for HIV Infection Open
Background Recent increases in syphilis among men who have sex with men (MSM) are especially concerning, given the biologic and epidemiologic associations between syphilis and HIV infection. We sought to better describe the current epidemi…