Hing Wai Tsang
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View article: Correction: Vitamin D status and its determinants among Chinese infants and toddlers in Hong Kong
Correction: Vitamin D status and its determinants among Chinese infants and toddlers in Hong Kong Open
View article: Vitamin D status and its determinants among Chinese infants and toddlers in Hong Kong
Vitamin D status and its determinants among Chinese infants and toddlers in Hong Kong Open
Purpose Vitamin D is a micronutrient that is necessary for bone health as well as the regulation of mineral homeostasis. This study aims to assess the vitamin D status and its determinants among infants and toddlers in Hong Kong, two of th…
View article: Evaluation of bronchial hyperresponsiveness in asthmatic paediatric patients using mannitol challenge test – Impacts of body mass index
Evaluation of bronchial hyperresponsiveness in asthmatic paediatric patients using mannitol challenge test – Impacts of body mass index Open
A high prevalence of AHR (>50%) was found in asthmatic children who self-evaluated with good asthma control. No significant influence of the BMI on the AHR severity could be demonstrated in this population with the "indirect" mannitol chal…
View article: The protective role of vitamin D in BNT162b2 vaccine-related acute myocarditis
The protective role of vitamin D in BNT162b2 vaccine-related acute myocarditis Open
Introduction Vaccine-related myocarditis is recognized as a rare but important complication, especially after mass-scale mRNA COVID-19 vaccination. Knowledge regarding how to minimize the risk is limited. As NK cells can mediate acute myoc…
View article: Husband involvement in antenatal care moderates the link between vitamin D status and depressive symptoms in pregnant women
Husband involvement in antenatal care moderates the link between vitamin D status and depressive symptoms in pregnant women Open
Aims The association between a pregnant mother’s vitamin D status and depressive symptoms has yielded inconsistent results. It is possible that other factors play a role in this association, as depression can have multiple causes. Recogniz…
View article: Genome-wide association study of BNT162b2 vaccine-related myocarditis identifies potential predisposing functional areas in Hong Kong adolescents
Genome-wide association study of BNT162b2 vaccine-related myocarditis identifies potential predisposing functional areas in Hong Kong adolescents Open
View article: A systematic review on the applicability of cell‐free DNA level as an obesity biomarker
A systematic review on the applicability of cell‐free DNA level as an obesity biomarker Open
Summary Obesity has become a global health concern in recent decades. Utilizing biomarkers presents a promising approach to comprehensively monitor the progress of obesity and its associated health conditions. This review aims to synthesiz…
View article: The central role of natural killer cells in mediating acute myocarditis after mRNA COVID-19 vaccination
The central role of natural killer cells in mediating acute myocarditis after mRNA COVID-19 vaccination Open
View article: Association of vitamin D‐binding protein polymorphisms and serum 25(OH)D concentration varies among Chinese healthy infants of different <scp>VDR‐FokI</scp> genotypes: A multi‐centre cross‐sectional study
Association of vitamin D‐binding protein polymorphisms and serum 25(OH)D concentration varies among Chinese healthy infants of different <span>VDR‐FokI</span> genotypes: A multi‐centre cross‐sectional study Open
Hypovitaminosis D during infancy is associated with the development of chronic diseases and poor health later in life. While the effect of environmental factors on vitamin D concentration has been extensively explored, this study aimed to …
View article: Natural history of infants with vitamin D deficiency in Hong Kong.
Natural history of infants with vitamin D deficiency in Hong Kong. Open
Persistent VDD is common among infants exclusively breastfeeding and those who did not receive vitamin D supplementation.
View article: Sleep quality mediates the relationship between systemic inflammation and neurocognitive performance
Sleep quality mediates the relationship between systemic inflammation and neurocognitive performance Open
View article: Sex Differences in Association Between Gut Microbiome and Essential Hypertension Based on Ambulatory Blood Pressure Monitoring
Sex Differences in Association Between Gut Microbiome and Essential Hypertension Based on Ambulatory Blood Pressure Monitoring Open
Background: Sex differences in the pathogenesis of hypertension exist. While gut microbiota (GM) has been associated with hypertension, it is unclear whether there are sex-linked differences in the association between GM and hypertension. …
View article: Evidence of individual differences in the long-term social, psychological, and cognitive consequences of child maltreatment
Evidence of individual differences in the long-term social, psychological, and cognitive consequences of child maltreatment Open
View article: Family Financial Pressure in Childhood and Telomere Length in Early Adolescence: A Prospective Study
Family Financial Pressure in Childhood and Telomere Length in Early Adolescence: A Prospective Study Open
Much research on children in high-risk environments has focused on the biological consequences of maltreatment, adversity, and trauma. Whether other early-life stress sources such as family financial hardship are implicated in the cellular…
View article: Risk factors for carriage of antimicrobial-resistant bacteria in community dwelling-children in the Asia-Pacific region: a systematic review and meta-analysis
Risk factors for carriage of antimicrobial-resistant bacteria in community dwelling-children in the Asia-Pacific region: a systematic review and meta-analysis Open
Background Antimicrobial resistance is an increasingly important issue in public health as antibiotics are overused. Resistance to antimicrobial agents can pose significant challenges to infection treatment. Objectives To evaluate risk fac…
View article: Omicron variant susceptibility to neutralizing antibodies induced in children by natural SARS-CoV-2 infection or COVID-19 vaccine
Omicron variant susceptibility to neutralizing antibodies induced in children by natural SARS-CoV-2 infection or COVID-19 vaccine Open
The novel SARS-CoV-2 Omicron variant may increase the risk of re-infection and vaccine breakthrough infections as it possesses key mutations in the spike protein that affect neutralizing antibody response. Most studies on neutralization su…
View article: Transmembrane 29 (Tmem29), a Newly Identified Molecule Showed Downregulation in Hypoxic-Ischemic Brain Damage
Transmembrane 29 (Tmem29), a Newly Identified Molecule Showed Downregulation in Hypoxic-Ischemic Brain Damage Open
Transmembrane 29 (Tmem29) gene with unknown function is a gene located on the X chromosome of the mouse genome. The gene showed differential expression in the Vannucci neonatal hypoxic-ischemic mouse brain model. We found the gene expresse…
View article: Assessment of SARS-CoV-2 Immunity in Convalescent Children and Adolescents
Assessment of SARS-CoV-2 Immunity in Convalescent Children and Adolescents Open
Persistence of protective immunity for SARS-CoV-2 is important against reinfection. Knowledge on SARS-CoV-2 immunity in pediatric patients is currently lacking. We opted to assess the SARS-CoV-2 adaptive immunity in recovered children and …
View article: Epidemiology of Acute Myocarditis/Pericarditis in Hong Kong Adolescents Following Comirnaty Vaccination
Epidemiology of Acute Myocarditis/Pericarditis in Hong Kong Adolescents Following Comirnaty Vaccination Open
Background Age-specific incidence of acute myocarditis/pericarditis in adolescents following Comirnaty vaccination in Asia is lacking. This study aimed to study the clinical characteristics and incidence of acute myocarditis/pericarditis a…
View article: Impact of Snoring on Telomere Shortening in Adolescents with Atopic Diseases
Impact of Snoring on Telomere Shortening in Adolescents with Atopic Diseases Open
Atopic diseases can impose a significant burden on children and adolescents. Telomere length is a cellular marker of aging reflecting the impact of cumulative stress exposure on individual health. Since elevated oxidative stress and inflam…
View article: Impact of COVID-19 Pandemic on Serum Vitamin D Level among Infants and Toddlers: An Interrupted Time Series Analysis and before-and-after Comparison
Impact of COVID-19 Pandemic on Serum Vitamin D Level among Infants and Toddlers: An Interrupted Time Series Analysis and before-and-after Comparison Open
Background: During the coronavirus disease 2019 (COVID-19) pandemic, the implementation of social distancing and home confinement measures may elevate the risk of vitamin D deficiency particularly for infants. This study aimed to quantify …
View article: An Assessment of Risk Factors for Insufficient Levels of Vitamin D during Early Infancy
An Assessment of Risk Factors for Insufficient Levels of Vitamin D during Early Infancy Open
Recent evidence suggests that breastfeeding may increase the risk of vitamin D deficiency in offspring. However, it is unclear whether increased risk results from breastfeeding alone, or whether it is associated together with other risk fa…
View article: Influence of Maternal Infection and Pregnancy Complications on Cord Blood Telomere Length
Influence of Maternal Infection and Pregnancy Complications on Cord Blood Telomere Length Open
Background . Exposure to suboptimal intrauterine environment might induce structural and functional changes that can affect neonatal health. Telomere length as an important indicator of cellular health has been associated with increased ri…
View article: Predictive biomarkers and tumor microenvironment in female genital melanomas: a multi-institutional study of 55 cases
Predictive biomarkers and tumor microenvironment in female genital melanomas: a multi-institutional study of 55 cases Open
View article: 12 Validation of a novel definition of low disease activity state in systemic lupus erythematosus
12 Validation of a novel definition of low disease activity state in systemic lupus erythematosus Open
Background and aims While a "Treat-to-target" principle is widely advocated in management of systemic lupus erythematosus (SLE), there is currently no internationally agreed definition of low disease activity in lupus. In 2015, the Asia-Pa…