Explanipedia

Current evidence and ongoing trials for surgery versus stereotactic body radiation therapy (SBRT) for early-stage non-small cell lung cancer: a narrative review Open

Lauren Drake, Robert Timmerman, Hiran C. Fernando · 2025

The current evidence favors surgery over SBRT for early-stage NSCLC in terms of OS, especially for standard-risk operable patients. For high-risk operable patients, surgery should still be considered standard of care, however the evidence …

Initial outcomes with uniportal video-assisted lung resection Open

James Shahoud, Benny Weksler, Brent A. Williams, Lawrence Crist, Hiran C. Fernando · 2025

OBJECTIVES Uniportal video-assisted lung resection is increasingly reported, but adoption in North America has been low. This study examines the early experience with the uniportal technique by a surgeon experienced in multiportal thoracos…

Multidisciplinary international expert consensus on perioperative airway management Open

Hengrui Liang, Guowei Che, Fei Cui, Junguo Dong, Weiquan Gu , et al. · 2025

This expert consensus provides a valuable reference for clinical practice. Further technological optimization and clinical research are needed to improve perioperative airway management.

Sublobectomy versus lobectomy for peripheral small-sized pulmonary mucinous adenocarcinoma Open

Zhen Yang, Fujun Yang, Zhaoxun Li, Hiran C. Fernando, Xiang Li , et al. · 2025

For peripheral small-sized PMA, sublobectomy yielded an RFS and OS comparable to those of lobectomy.

Uniportal video-assisted lung resection versus robotic-assisted lung resection, is there a difference? Open

James Shahoud, Benny Weksler, Brent A. Williams, Conor M. Maxwell, Hiran C. Fernando · 2024

UVATS and RATS lung resections were associated with similar post-operative adverse event rates. Lymph node dissection and length of stay were improved with RATS. Oncological outcomes were similar. UVATS was associated with lower morphine r…

Application of drainage strategy with bi-pigtail catheters in patients undergoing lobectomy by uniportal video-assisted thoracic surgery Open

Pingwen Yu, Davor Stamenovic, Hiran C. Fernando, Hongxu Liu · 2024

Our drainage strategy with BPCs decreased the incidence of postoperative complications and alleviated the postoperative pain of patients undergoing lobectomy by uniportal VATS and is safe and feasible.

Re-operation after prior esophagomyotomy Open

Abdulrahman Y. Hammad, Sean C. Forrest, Hiran C. Fernando · 2024

Outcomes following minimally invasive approaches vs. open extended lobectomy for non-small cell lung cancer: a propensity-matched analysis of the National Cancer Database Open

Tangbing Chen, Ernest G. Chan, Binhao Huang, Luca Bertolaccini, Hiran C. Fernando , et al. · 2024

The results of our study suggest that MIS for extended lobectomy not only is safe and feasible but also is oncologically effective. However, it is imperative to note that these encouraging findings necessitate further validation through pr…

Commentary: is segmentectomy curative in patients with early-stage ground glass opacity predominant non-small cell lung cancer? Open

Abdulrahman Y. Hammad, Hiran C. Fernando · 2024

Comprehensive value implications of surgeon volume for lung cancer surgery: Use of an analytic framework within a regional health system Open

Conor M. Maxwell, Akash M. Bhat, Samantha J. Falls, Matthew Bigbee, Yue Yin , et al. · 2023

Resect a little, resect more, irradiate or ablate—what is the best approach? Open

Conor M. Maxwell, Hiran C. Fernando · 2022

The effect of enhanced recovery after minimally invasive esophagectomy: a randomized controlled trial Open

Yaxing Shen, Xiaosang Chen, Junyi Hou, Youwen Chen, Yong Fang , et al. · 2022

Background The purpose of this randomized controlled trial was to determine if enhanced recovery after surgery (ERAS) would improve outcomes for three-stage minimally invasive esophagectomy (MIE). Methods Patients with esophageal cancer un…

Bronchoscopic Intra-Pleural Instillation of Fibrin Glue and Autologous Blood to Manage Persistent Air Leaks after Lung Resection Open

Giorgio Maria Ferraroli, Gianluca Perroni, Veronica Maria Giudici, Alberto Antonicelli, Hiran C. Fernando , et al. · 2022

Background: Persistent air leak is a common complication after lung resection causing prolonged length of stay and increased healthcare costs. Surgical intervention can be an option, but other more conservative approaches should be conside…

Endoscopic palliation of esophageal cancer: a narrative review apart from stenting Open

Danjing Zhao, Kevin Shahbahrami, Hiran C. Fernando · 2021

Pathological complete response after neoadjuvant treatment determines survival in esophageal squamous cell carcinoma patients (NEOCRTEC5010) Open

Jianfei Shen, Min Kong, Hong Yang, Ke Jin, Yuping Chen , et al. · 2021

pCR after nCRT is an important prognostic indicator of OS and DFS in patients with ESCC. In addition, lymph-node status could represent an important parameter in the prognostic evaluation of esophageal cancer patients.

Implementation of eras for patients undergoing esophagectomy: a narrative review of the current literature and latest evidence Open

Gianluca Perroni, Christopher Johnson, Sandeep J. Khandhar, Paolo Veronesi, Vincenzo Ambrogi , et al. · 2021

Gianluca Perroni, Christopher Johnson, Sandeep Khandhar, Giulia Veronesi, Vincenzo Ambrogi, Hiran C. Fernando

Prediction of Driver Gene Matching in Lung Cancer NOG/PDX Models Based on Artificial Intelligence Open

Yayi He, Haoyue Guo, Li Diao, Yu Chen, Junjie Zhu , et al. · 2021

Multifactorial dysphagia: Azygos vein aneurysm (AVA) and esophagogastric junction outflow obstruction (EGJOO) Open

Scott Morton, Andrew D. Grubic, Shahin Ayazi, Satish C. Muluk, Hiran C. Fernando , et al. · 2021

Derivation and validation of a nomogram model for pulmonary thromboembolism in patients undergoing lung cancer surgery Open

Yuping Li, Lei Shen, Junrong Ding, Dong Xie, Jian Yang , et al. · 2021

A high-performance nomogram was established on the risk factors for PTE in patients undergoing lung cancer surgery. The nomogram could be used to provide an individual risk assessment and guide prophylaxis decisions for patients. Further e…

Laparoscopic anti-reflux operation: fundoplication vs. Linx—techniques and outcomes Open

Helene M. Sterbling, Hiran C. Fernando · 2021

To date, the treatment of gastroesophageal reflux disease consists of lifestyle modifications, medical management through proton pump inhibitors or H2 receptor blockers, and for refractory cases, surgery. The gold standard for surgical int…

Sternal reconstruction—a rare but challenging issue for thoracic surgeons Open

Hiran C. Fernando · 2020

Fibrin sealant for esophageal anastomosis: A phase II study Open

Yaobin Lin, Jianhua Fu, Yan Huang, Yihuai Hu, Kongjia Luo , et al. · 2020

Perioperative sealing with porcine FS appears safe and may prevent AL after esophagectomy in patients with resectable EC or EJC. Further phase III studies are warranted.

Multicenter Study of Metastatic Lung Tumors Targeted by Interventional Cryoablation Evaluation (SOLSTICE) Open

Matthew R. Callstrom, David A. Woodrum, Francis C. Nichols, Jean Palussière, Xavier Buy , et al. · 2020

CT Densitometry and Morphology of Radiofrequency-Ablated Stage IA Non–Small Cell Lung Cancer: Results from the American College of Surgeons Oncology Group Z4033 (Alliance) Trial Open

Erica S. Alexander, Lillian Xiong, Grayson L. Baird, Hiran C. Fernando, Damian E. Dupuy · 2020

Clinical guidelines on perioperative management strategies for enhanced recovery after lung surgery Open

Shugeng Gao, Serena Barello, Liang Chen, Chun Chen, Guowei Che , et al. · 2019

Advances in thoracic surgery, especially the popularization of minimally invasive techniques, have dramatically expanded or changed the concept of surgical treatment. Early recovery from thoracic surgery is now routine. In Jan 2019, the Eu…

Peripheral Blood Lymphocytes and Platelets Are Prognostic in Surgical pT1 Non-Small Cell Lung Cancer Open

Anita Sulibhavi, Sainath Asokan, Matthew I. Miller, Paulo César Moreira, Benedict D.T. Daly , et al. · 2019

Potential advantage of digital drainage systems using a low-suction approach after video-assisted thoracoscopic surgery lobectomy Open

Hiran C. Fernando · 2019

Holbek et al . recently reported the results of a randomized controlled trial comparing their standard suction to low suction approach after video-assisted thoracoscopic surgery (VATS) lobectomy (1). The investigators used the Thopaz digi…

Corrigendum to ‘Uniportal video-assisted thoracic surgery lobectomy: a consensus report from the Uniportal VATS Interest Group (UVIG) of the European Society of Thoracic Surgeons (ESTS)’ [Eur J Cardiothorac Surg 2019;56:224–9] Open

Luca Bertolaccini, Hasan Fevzi Batırel, Alessandro Brunelli, Diego González-Rivas, Mahmoud Ismail , et al. · 2019

Sa1137 – Liquid Nitrogen Spray Cryotherapy Eradicates Dysplasia in 87% and Intestinal Metaplasia in 65% of Patients with Barrett's Esophagus: Results of a U.S. Multicenter Registry Open

Swathi Eluri, Vivek Kaul, Matthew McKinley, Douglas K. Pleskow, Franklin Tsai , et al. · 2019

Selecting therapy for small ground-glass tumors—the potential role of volumetric computed tomography scan Open

Xiang-Wen Wu, Hiran C. Fernando · 2019

Shimada and colleagues have reported on the prognostic value of tumor solid-part size and solid-part volume in patients with clinical stage I non-small cell lung cancer (NSCLC) (1). In their study, the authors studied 252 patients with cli…

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