Hiren C. Patel
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View article: Enteric Fever in Children aged 1–14 years Socio-demographic Insights, Clinical Manifestations, and Outcomes from a 2-year Hospital-based Study
Enteric Fever in Children aged 1–14 years Socio-demographic Insights, Clinical Manifestations, and Outcomes from a 2-year Hospital-based Study Open
View article: Corticospinal tract damage on baseline CT predicts motor recovery and functional outcome in intracerebral haemorrhage
Corticospinal tract damage on baseline CT predicts motor recovery and functional outcome in intracerebral haemorrhage Open
Introduction: Corticospinal tract (CST) integrity can predict motor outcome after stroke but requires specialist investigations not routinely performed after intracerebral haemorrhage (ICH). We investigated the feasibility of identifying t…
View article: Reporting of angiographic studies in patients diagnosed with a cerebral arteriovenous malformation: a systematic review
Reporting of angiographic studies in patients diagnosed with a cerebral arteriovenous malformation: a systematic review Open
A cerebral arteriovenous malformation (cAVM) is an abnormal tangle of cerebral blood vessels. The consensus document by the Joint Writing Group (JWG) highlighted which cAVM features should be recorded. Subsequent publications have reported…
View article: Can angiogenesis be reliably determined on digital subtraction angiography in cerebral arteriovenous malformations?
Can angiogenesis be reliably determined on digital subtraction angiography in cerebral arteriovenous malformations? Open
We have demonstrated perinidal angiogenesis can be visualised on angiograms with moderate reliability, and that it may be related to angioarchitectural characteristics associated with venous hypertension.
View article: Reporting of angiographic studies in patients diagnosed with a cerebral arteriovenous malformation: a systematic review
Reporting of angiographic studies in patients diagnosed with a cerebral arteriovenous malformation: a systematic review Open
A cerebral arteriovenous malformation (cAVM) is an abnormal tangle of cerebral blood vessels. The consensus document by the Joint Writing Group (JWG) highlighted which cAVM features should be recorded. Subsequent publications have reported…
View article: Causal Graph Aided Causal Discovery in an Observational Aneurysmal Subarachnoid Hemorrhage Study
Causal Graph Aided Causal Discovery in an Observational Aneurysmal Subarachnoid Hemorrhage Study Open
Causal inference methods for observational data are increasingly recognized as a valuable complement to randomized clinical trials (RCTs). They can, under strong assumptions, emulate RCTs or help refine their focus. Our approach to causal …
View article: From Diagnostic CT to DTI Tractography labels: Using Deep Learning for Corticospinal Tract Injury Assessment and Outcome Prediction in Intracerebral Haemorrhage
From Diagnostic CT to DTI Tractography labels: Using Deep Learning for Corticospinal Tract Injury Assessment and Outcome Prediction in Intracerebral Haemorrhage Open
The preservation of the corticospinal tract (CST) is key to good motor recovery after stroke. The gold standard method of assessing the CST with imaging is diffusion tensor tractography. However, this is not available for most intracerebra…
View article: Psychoeducation Interventions after Brain Injury – A Scoping Review
Psychoeducation Interventions after Brain Injury – A Scoping Review Open
Background and aims: Psychoeducation is an intervention which involves structured disease specific information and support aimed at improving coping and understanding. Evidence has shown that this type of intervention improves outcome in m…
View article: Acute care bundles should be used for patients with intracerebral haemorrhage: An expert consensus statement
Acute care bundles should be used for patients with intracerebral haemorrhage: An expert consensus statement Open
Purpose: Intracerebral haemorrhage (ICH) is the most devastating form of stroke and a major cause of disability. Clinical trials of individual therapies have failed to definitively establish a specific beneficial treatment. However, clinic…
View article: Reporting of angiographic studies in patients diagnosed with a cerebral arteriovenous malformation: a systematic review
Reporting of angiographic studies in patients diagnosed with a cerebral arteriovenous malformation: a systematic review Open
A cerebral arteriovenous malformation (cAVM) is an abnormal tangle of cerebral blood vessels. The consensus document by the Joint Writing Group (JWG)
View article: Perioperative Means to Prevent Surgical Site Infections following Elective Craniotomies: A Single-Center Experience
Perioperative Means to Prevent Surgical Site Infections following Elective Craniotomies: A Single-Center Experience Open
Background Postoperative surgical site infections are a recognized complication following craniotomies with an associated increase in morbidity and mortality. Several studies have attempted to identify bundles of care to reduce the inciden…
View article: Risk of Aneurysm Rupture (ROAR) study: protocol for a long-term, longitudinal, UK multicentre study of unruptured intracranial aneurysms
Risk of Aneurysm Rupture (ROAR) study: protocol for a long-term, longitudinal, UK multicentre study of unruptured intracranial aneurysms Open
Introduction Unruptured intracranial aneurysms (UIA) are common in the adult population, but only a relatively small proportion will rupture. It is therefore essential to have accurate estimates of rupture risk to target treatment towards …
View article: WITHDRAWN: Reporting of angiographic studies in patients diagnosed with a cerebral Arteriovenous Malformation: A systematic review
WITHDRAWN: Reporting of angiographic studies in patients diagnosed with a cerebral Arteriovenous Malformation: A systematic review Open
This article has been withdrawn at the request of the authors. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/policies/article-wi…
View article: “QUANTIFYING POLY PHARMACOLOGY: SCORING FUNCTIONS AND COMPOSITE INDICES FOR AD MTDLS”
“QUANTIFYING POLY PHARMACOLOGY: SCORING FUNCTIONS AND COMPOSITE INDICES FOR AD MTDLS” Open
View article: Reliability and Validity of Gujarati Version of Drooling Impact Scale for Sialorrhea in Children with Neurological Impairment
Reliability and Validity of Gujarati Version of Drooling Impact Scale for Sialorrhea in Children with Neurological Impairment Open
View article: Scale-up of ABC care bundle for intracerebral haemorrhage across two hyperacute stroke units in one region in England: a mixed methods evaluation of a quality improvement project
Scale-up of ABC care bundle for intracerebral haemorrhage across two hyperacute stroke units in one region in England: a mixed methods evaluation of a quality improvement project Open
Background Intracerebral haemorrhage (ICH) accounts for 10%–15% of strokes in the UK, but is responsible for half of all annual global stroke deaths. The ABC bundle for ICH was developed and implemented at Salford Royal Hospital, and was a…
View article: Simple endovascular coiling: An effective long-term solution for wide-necked ruptured middle cerebral artery aneurysms? A 10-years retrospective study
Simple endovascular coiling: An effective long-term solution for wide-necked ruptured middle cerebral artery aneurysms? A 10-years retrospective study Open
Background Endovascular coiling is usually the first line treatment modality for most ruptured intracranial aneurysms. However, there is still some debate as to whether microsurgical clipping or coiling is the treatment of choice for compl…
View article: The Immune System's Role in the Consequences of Mild Traumatic Brain Injury (Concussion)
The Immune System's Role in the Consequences of Mild Traumatic Brain Injury (Concussion) Open
Mild traumatic brain injury (mild TBI), often referred to as concussion, is the most common form of TBI and affects millions of people each year. A history of mild TBI increases the risk of developing emotional and neurocognitive disorders…
View article: Are do-not-resuscitate orders associated with limitations of care beyond their intended purpose in patients with acute intracerebral haemorrhage? Analysis of the ABC-ICH study
Are do-not-resuscitate orders associated with limitations of care beyond their intended purpose in patients with acute intracerebral haemorrhage? Analysis of the ABC-ICH study Open
Implementation of an acute bundle of care for intracerebral haemorrhage (ICH) was associated with a marked improvement in survival at our centre, mediated by a reduction in early (<24 hours) do-not-resuscitate (DNR) orders. The aim of this…
View article: What do neurosurgical trainees think about neuro-interventional training and service provision in the United Kingdom?
What do neurosurgical trainees think about neuro-interventional training and service provision in the United Kingdom? Open
Background: There is a disparity between the number of interventional neuroradiologists (INRs) in the UK and the number needed to provide a comprehensive 24/7 interventional neurovascular service. It is recognized that trainees from other …
View article: Value of dynamic clinical and biomarker data for mortality risk prediction in COVID-19: a multicentre retrospective cohort study
Value of dynamic clinical and biomarker data for mortality risk prediction in COVID-19: a multicentre retrospective cohort study Open
Objectives Being able to predict which patients with COVID-19 are going to deteriorate is important to help identify patients for clinical and research practice. Clinical prediction models play a critical role in this process, but current …
View article: Anakinra in COVID-19: important considerations for clinical trials
Anakinra in COVID-19: important considerations for clinical trials Open
View article: Issue Information
Issue Information Open
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View article: An Intracerebral Hemorrhage Care Bundle Is Associated with Lower Case Fatality
An Intracerebral Hemorrhage Care Bundle Is Associated with Lower Case Fatality Open
Objective Anticoagulation reversal, intensive blood pressure lowering, neurosurgery, and access to critical care might all be beneficial in acute intracerebral hemorrhage (ICH). We combined and implemented these as the “ABC” hyperacute car…
View article: Efficacy and safety of minimally invasive surgery with thrombolysis in intracerebral haemorrhage evacuation (MISTIE III): a randomised, controlled, open-label, blinded endpoint phase 3 trial
Efficacy and safety of minimally invasive surgery with thrombolysis in intracerebral haemorrhage evacuation (MISTIE III): a randomised, controlled, open-label, blinded endpoint phase 3 trial Open
View article: Predictors of Outcome in Aneurysmal Subarachnoid Hemorrhage Patients
Predictors of Outcome in Aneurysmal Subarachnoid Hemorrhage Patients Open
Background and Purpose— The mortality and morbidity after aneurysmal subarachnoid hemorrhage has improved because of better diagnosis, early treatment to secure the aneurysm, and better management of disease-specific complications. With th…
View article: CSF inflammatory response after intraventricular hemorrhage
CSF inflammatory response after intraventricular hemorrhage Open
NCT00784134.
View article: What Factors Determine Treatment Outcome in Aneurysmal Subarachnoid Hemorrhage in the Modern Era? A Post Hoc STASH Analysis
What Factors Determine Treatment Outcome in Aneurysmal Subarachnoid Hemorrhage in the Modern Era? A Post Hoc STASH Analysis Open
View article: Reduction of inflammation after administration of interleukin-1 receptor antagonist following aneurysmal subarachnoid hemorrhage: results of the Subcutaneous Interleukin-1Ra in SAH (SCIL-SAH) study
Reduction of inflammation after administration of interleukin-1 receptor antagonist following aneurysmal subarachnoid hemorrhage: results of the Subcutaneous Interleukin-1Ra in SAH (SCIL-SAH) study Open
OBJECTIVE Aneurysmal subarachnoid hemorrhage (aSAH) is a devastating cerebrovascular event with long-term morbidity and mortality. Patients who survive the initial bleeding are likely to suffer further early brain injury arising from a ple…