Hiroaki Yazawa
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View article: POS1362 JANUS KINASE INHIBITOR SUPPRESSES TNF-α and IL-6-INDUCED OSTEOCLAST DIFFERENTIATION, BUT NOT RANKL-INDUCED OSTEOCLAST DIFFERENTIATION, AND REDUCES BONE DESTRUCTION IN PATIENTS WITH RHEUMATOID ARTHRITIS
POS1362 JANUS KINASE INHIBITOR SUPPRESSES TNF-α and IL-6-INDUCED OSTEOCLAST DIFFERENTIATION, BUT NOT RANKL-INDUCED OSTEOCLAST DIFFERENTIATION, AND REDUCES BONE DESTRUCTION IN PATIENTS WITH RHEUMATOID ARTHRITIS Open
View article: New-onset of rheumatic diseases following COVID-19 vaccination: the report of three cases and a literature review
New-onset of rheumatic diseases following COVID-19 vaccination: the report of three cases and a literature review Open
Vaccines against coronavirus disease 2019 (COVID-19) have been distributed in most countries for the prevention of onset and aggravation of COVID-19. Recently, there have been increasing numbers of reports on new-onset autoimmune and autoi…
View article: Successful Treatment of Diffuse Large B-cell Lymphoma Involving Multiple Renal and Bone Infiltrations Presenting with Giant Cell Arteritis-like Manifestations
Successful Treatment of Diffuse Large B-cell Lymphoma Involving Multiple Renal and Bone Infiltrations Presenting with Giant Cell Arteritis-like Manifestations Open
We herein report a case of diffuse large B-cell lymphoma (DLBCL) involving multiple renal and bone infiltrations presenting with giant cell arteritis (GCA)-like manifestations. One month prior, the present patient had left-sided temporal h…
View article: Perihepatitis as an Initial Manifestation of Systemic Lupus Erythematosus
Perihepatitis as an Initial Manifestation of Systemic Lupus Erythematosus Open
A 25-year-old man presented with a fever and right upper quadrant abdominal pain. Computed tomography (CT) of the abdomen revealed diffuse perihepatic capsular enhancement, suggesting perihepatitis. Although the patient was a man, Fitz-Hug…
View article: POS1042 JANUS KINASE INHIBITOR SUPPRESSES THE DIFFERENTIATION AND FUNCTION OF TUMOR NECROSIS FACTOR-ALPHA AND INTERLEUKIN-6- INDUCED OSTEOCLASTS IN PERIPHERAL BLOOD MONOCYTES FROM PATIENTS WITH RHEUMATOID ARTHRITIS
POS1042 JANUS KINASE INHIBITOR SUPPRESSES THE DIFFERENTIATION AND FUNCTION OF TUMOR NECROSIS FACTOR-ALPHA AND INTERLEUKIN-6- INDUCED OSTEOCLASTS IN PERIPHERAL BLOOD MONOCYTES FROM PATIENTS WITH RHEUMATOID ARTHRITIS Open
Background We have previously reported that stimulation of mouse bone marrow–derived macrophages with tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) induces differentiation of osteoclast-like cells having bone resorption ability<…
View article: Evaluation of an immunochromatography-based rapid antigen test, Inspecter Kowa® SARS-CoV-2, using saliva specimens for the detection of SARS-CoV-2
Evaluation of an immunochromatography-based rapid antigen test, Inspecter Kowa® SARS-CoV-2, using saliva specimens for the detection of SARS-CoV-2 Open
View article: New-onset Adult-onset Still's Disease Following COVID-19 Vaccination: Three Case Reports and a Literature Review
New-onset Adult-onset Still's Disease Following COVID-19 Vaccination: Three Case Reports and a Literature Review Open
Since December 2020, coronavirus disease 2019 (COVID-19) vaccines have been distributed in most countries to prevent the onset and aggravation of COVID-19. There is little information regarding the long-term safety of the vaccines. We repo…
View article: Dual effects of interleukin-10 on natural killer cells and monocytes and the implications for adult-onset Still's disease
Dual effects of interleukin-10 on natural killer cells and monocytes and the implications for adult-onset Still's disease Open
IL-10 evidently has dual effects on NK cells (stimulation) and on monocytes (inhibition). Better understanding the roles of the cytokine network would shed light on the pathogenesis of AOSD.
View article: Efficacy, safety, and adherence of tocilizumab therapy in elderly patients with rheumatoid arthritis: A real-world observational study
Efficacy, safety, and adherence of tocilizumab therapy in elderly patients with rheumatoid arthritis: A real-world observational study Open
Objective: We evaluated the efficacy, safety, and drug survival rate of tocilizumab in the elderly patients with rheumatoid arthritis (RA). Methods: This study was conducted in 108 RA patients who started tocilizumab between 2008 and 2018.…
View article: THU0050 IMPLICATIONS OF THE DIFFERENT RESPONSES OF NK CELLS AND MONOCYTES TO IL-6 AND IL-10 IN THE PATHOGENESIS OF ADULT-ONSET STILL'S DISEASE
THU0050 IMPLICATIONS OF THE DIFFERENT RESPONSES OF NK CELLS AND MONOCYTES TO IL-6 AND IL-10 IN THE PATHOGENESIS OF ADULT-ONSET STILL'S DISEASE Open
View article: AB0148 OSTEOBLASTS SECRETE A HIGH LEVEL OF OSTEOPROTEGERINE AND SUPPRESS OSTEOCLASTOGENESIS BY INHIBITING SOLUBLE RANKL – IMPLICATIONS FOR THE PATHOGENESIS OF RHEUMATOID ARTHRITIS
AB0148 OSTEOBLASTS SECRETE A HIGH LEVEL OF OSTEOPROTEGERINE AND SUPPRESS OSTEOCLASTOGENESIS BY INHIBITING SOLUBLE RANKL – IMPLICATIONS FOR THE PATHOGENESIS OF RHEUMATOID ARTHRITIS Open
View article: Osteomyelitis due to methicillin-resistant <i>Staphylococcus aureus</i> successfully treated by an oral combination of minocycline and trimethoprim–sulfamethoxazole
Osteomyelitis due to methicillin-resistant <i>Staphylococcus aureus</i> successfully treated by an oral combination of minocycline and trimethoprim–sulfamethoxazole Open
Most of the anti-methicillin-resistant Staphylococcus aureus drugs available in Japan are administered intravenously, except for linezolid, which can also be administered orally. Here, we report a lupus patient with methicillin-resistant S…
View article: AB0095 Attempt to develop a chimeric co-culture system to differentiate mouse osteoclasts by culturing mouse precursor cells with human synovial fibroblasts
AB0095 Attempt to develop a chimeric co-culture system to differentiate mouse osteoclasts by culturing mouse precursor cells with human synovial fibroblasts Open
View article: AB0066 Combination of il-10 and il-18 but not il-6 and il-18 induces ifn-gamma production and surface expression of trail on nk cells
AB0066 Combination of il-10 and il-18 but not il-6 and il-18 induces ifn-gamma production and surface expression of trail on nk cells Open