Hirohide Iwasaki
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View article: Optimizing anatomy dissection teams using the Yukari method: A peer compatibility‐based approach
Optimizing anatomy dissection teams using the Yukari method: A peer compatibility‐based approach Open
Human anatomy dissection serves as a cornerstone of medical education, fostering not only anatomical knowledge but also teamwork and professionalism. Given the considerable intellectual, physical, and emotional demands of dissection, effec…
View article: Integrated Profiling of Synaptic E/I Balance Reveals Altered Synaptic Organization and Phenotypic Variability in a Prenatal ASD Model
Integrated Profiling of Synaptic E/I Balance Reveals Altered Synaptic Organization and Phenotypic Variability in a Prenatal ASD Model Open
Proper regulation of excitation and inhibition (E/I balance) is essential for maintaining stable neural circuit function and flexible behavior. Disruptions of E/I balance have been implicated in a variety of neurodevelopmental and psychiat…
View article: Interaction between Teneurin-2 and microtubules via EB proteins provides a platform for GABAA receptor exocytosis
Interaction between Teneurin-2 and microtubules via EB proteins provides a platform for GABAA receptor exocytosis Open
Neurons form dense neural circuits by connecting to each other via synapses and exchange information through synaptic receptors to sustain brain activities. Excitatory postsynapses form and mature on spines composed predominantly of actin,…
View article: Author response: Interaction between Teneurin-2 and microtubules via EB proteins provides a platform for GABAA receptor exocytosis
Author response: Interaction between Teneurin-2 and microtubules via EB proteins provides a platform for GABAA receptor exocytosis Open
Full text Figures and data Side by side Abstract Editor's evaluation Introduction Results Discussion Materials and methods Data availability References Decision letter Author response Article and author information Metrics Abstract Neurons…
View article: Editorial: Cutting-edge technologies for the comprehensive analysis of neural circuits
Editorial: Cutting-edge technologies for the comprehensive analysis of neural circuits Open
EDITORIAL article Front. Neuroanat., 05 December 2022 Volume 16 - 2022 | https://doi.org/10.3389/fnana.2022.1101560
View article: Recent technological advances in correlative light and electron microscopy for the comprehensive analysis of neural circuits
Recent technological advances in correlative light and electron microscopy for the comprehensive analysis of neural circuits Open
Light microscopy (LM) covers a relatively wide area and is suitable for observing the entire neuronal network. However, resolution of LM is insufficient to identify synapses and determine whether neighboring neurons are connected via synap…
View article: Teneurin-2 at the Synapse Construction Site is a Signpost for Cargo Unloading from Motor Proteins
Teneurin-2 at the Synapse Construction Site is a Signpost for Cargo Unloading from Motor Proteins Open
In mature neurons, excitatory synapses are formed on the dendritic spine, whereas inhibitory synapses are formed on the dendritic shaft. Thus, it is primarily the accumulation of synaptic proteins that characterizes inhibitory synapses as …
View article: Insight into the function of a unique voltage-sensor protein (TMEM266) and its short form in mouse cerebellum
Insight into the function of a unique voltage-sensor protein (TMEM266) and its short form in mouse cerebellum Open
Voltage-sensing proteins generally consist of voltage-sensor domains and pore-gate domains, forming the voltage-gated ion channels. However, there are several unconventional voltage-sensor proteins that lack pore-gate domains, conferring t…
View article: Correlative microscopy and block-face imaging (CoMBI) method for both paraffin-embedded and frozen specimens
Correlative microscopy and block-face imaging (CoMBI) method for both paraffin-embedded and frozen specimens Open
View article: Comprehensive Profiling of Gene Expression in the Cerebral Cortex and Striatum of BTBRTF/ArtRbrc Mice Compared to C57BL/6J Mice
Comprehensive Profiling of Gene Expression in the Cerebral Cortex and Striatum of BTBRTF/ArtRbrc Mice Compared to C57BL/6J Mice Open
Mouse line BTBR T + Iptr3 tf /J (hereafter referred as to BTBR/J) is a mouse strain that shows lower sociability compared to the C57BL/6J mouse strain (B6) and thus is often utilized as a model for autism spectrum disorder (ASD). In this s…
View article: Understanding the Principles of Neural Circuit Formation
Understanding the Principles of Neural Circuit Formation Open
View article: Geometry and the Organizational Principle of Spine Synapses along a Dendrite
Geometry and the Organizational Principle of Spine Synapses along a Dendrite Open
Precise information on synapse organization in a dendrite is crucial to understanding the mechanisms underlying voltage integration and the variability in the strength of synaptic inputs across dendrites of different complex morphologies. …
View article: Developmental stage-dependent regulation of spine formation by calcium-calmodulin-dependent protein kinase IIα and Rap1
Developmental stage-dependent regulation of spine formation by calcium-calmodulin-dependent protein kinase IIα and Rap1 Open
The roles of calcium-calmodulin-dependent protein kinase II-alpha (CaMKIIα) in the expression of long-term synaptic plasticity in the adult brain have been extensively studied. However, how increased CaMKIIα activity controls the maturatio…