Explanipedia

Mitochondria-dependent ferroptosis plays a pivotal role in doxorubicin cardiotoxicity Open

Tomonori Tadokoro, Masataka Ikeda, Tomomi Ide, Hiroko Deguchi, Soichiro Ikeda , et al. · 2023

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Mitochondria-dependent ferroptosis plays a pivotal role in doxorubicin cardiotoxicity Open

Tomonori Tadokoro, Masataka Ikeda, Tomomi Ide, Hiroko Deguchi, Soichiro Ikeda , et al. · 2020

Doxorubicin (DOX), a chemotherapeutic agent, induces a cardiotoxicity referred to as doxorubicin-induced cardiomyopathy (DIC). This cardiotoxicity often limits chemotherapy for malignancies and is associated with poor prognosis. However, t…

Roxadustat Markedly Reduces Myocardial Ischemia Reperfusion Injury in Mice Open

Hiroko Deguchi, Masataka Ikeda, Tomomi Ide, Tomonori Tadokoro, Soichiro Ikeda , et al. · 2020

RXD pretreatment may be a novel strategy against I/R injury.

Blockade of L-type Ca2+ channel attenuates doxorubicin-induced cardiomyopathy via suppression of CaMKII-NF-κB pathway Open

Soichiro Ikeda, Shouji Matsushima, Kosuke Okabe, Masataka Ikeda, Akihito Ishikita , et al. · 2019

Ca 2+ /calmodulin-dependent protein kinase II (CaMKII) and nuclear factor-kappa B (NF-κB) play crucial roles in pathogenesis of doxorubicin (DOX)-induced cardiomyopathy. Their activities are regulated by intracellular Ca 2+ . We hypothesiz…

A Case of Cardiac Sarcoidosis; Clinical History Led to the Definitive Diagnosis Open

Hiroko Deguchi, Ryuichi Matsukawa, Yasuhiro Sudutsu, Masato Katsuki, Y Kuribayashi , et al. · 2016

EXTRACTION OF ITEMS FOR FUTURE DISCUSSION ON ASSISTIVE MEASURES FOR SHOPPING-CHALLENGED BASED ON SURVEY OF INHABITANTS' GOING-OUT BEHAVIOR IN AGED AND DEPOPULATED AREA- A case study in Misugi Town, Tsu City, Mie Prefecture - Open

Hiroko Deguchi, Hidemasa YOSHIMURA · 2015

Hiroko Deguchi YOU? Author Swipe