Hiroshi Deguchi
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View article: Gosha-Jinki-Gan Reduces Inflammation in Chronic Ischemic Stroke Mouse Models by Suppressing the Infiltration of Macrophages
Gosha-Jinki-Gan Reduces Inflammation in Chronic Ischemic Stroke Mouse Models by Suppressing the Infiltration of Macrophages Open
Ischemic stroke is a primary cause of cerebrovascular diseases and continues to be one of the leading causes of death and disability among patients worldwide. Pathological processes caused by vascular damage due to stroke occur in a time-d…
View article: MEASUREMENT OF SPATIO-TEMPORAL DISTRIBUTION OF WAVE RUNUP AT AKI FISHING PORT USING A FIXED CAMERA
MEASUREMENT OF SPATIO-TEMPORAL DISTRIBUTION OF WAVE RUNUP AT AKI FISHING PORT USING A FIXED CAMERA Open
View article: OC 22.2 Endothelial Activation and Von Willebrand Factor Role in COVID-19- Associated Coagulopathy
OC 22.2 Endothelial Activation and Von Willebrand Factor Role in COVID-19- Associated Coagulopathy Open
View article: Corrosion behavior of carbon steel covered with a coating film containing metallic compounds under a sulfuric acid mist environment containing chloride
Corrosion behavior of carbon steel covered with a coating film containing metallic compounds under a sulfuric acid mist environment containing chloride Open
The corrosion behavior of carbon steel covered with coating films containing Al 2 (SO 4 ) 3 , CaO, and BaO was examined under a sulfuric acid mist environment containing chloride. CaSO 4 ･2H 2 O and BaSO 4 were formed as the corrosion prod…
View article: Agent-based model using GPS analysis for infection spread and inhibition mechanism of SARS-CoV-2 in Tokyo
Agent-based model using GPS analysis for infection spread and inhibition mechanism of SARS-CoV-2 in Tokyo Open
Analyzing the SARS-CoV-2 pandemic outbreak based on actual data while reflecting the characteristics of the real city provides beneficial information for taking reasonable infection control measures in the future. We demonstrate agent-base…
View article: Sex-Specific Differences in the Pathogenesis, Endothelial Dysfunction, and Hypercoagulability of Sars-Cov-2 Infection in K18-hACE2 Mice
Sex-Specific Differences in the Pathogenesis, Endothelial Dysfunction, and Hypercoagulability of Sars-Cov-2 Infection in K18-hACE2 Mice Open
The pathogenesis of coronavirus disease 2019 (COVID-19) complications in critically ill patients involve virus-mediated cellular damage in infected tissue and secondary organ damage associated with a hyperinflammatory response. The proinfl…
View article: Hemorrhagic shock and tissue injury provoke distinct components of trauma-induced coagulopathy in a swine model
Hemorrhagic shock and tissue injury provoke distinct components of trauma-induced coagulopathy in a swine model Open
View article: Simulating the influence of Facebook fan pages on individual attitudes toward vaccination using agent‐based modelling
Simulating the influence of Facebook fan pages on individual attitudes toward vaccination using agent‐based modelling Open
The anti‐vaccination movement is dangerous because of its influence on vaccine hesitancy. Nowadays, social media platforms become significant sources of anti‐vaccination information; therefore, combating their proliferation needs to be add…
View article: Agent-based model using GPS analysis for infection spread and inhibition mechanism of SARS-CoV-2 in Tokyo
Agent-based model using GPS analysis for infection spread and inhibition mechanism of SARS-CoV-2 in Tokyo Open
Analyzing the SARS-CoV-2 pandemic outbreak based on actual data while reflecting the characteristics of the real city provides beneficial information for taking reasonable infection control measures in the future. We demonstrate agent-base…
View article: Agent-based model using GPS analysis for infection spread and inhibition mechanism of SARS-CoV-2 in Tokyo
Agent-based model using GPS analysis for infection spread and inhibition mechanism of SARS-CoV-2 in Tokyo Open
Analyzing the SARS-CoV-2 pandemic outbreak based on actual data while reflecting the characteristics of the real city provides beneficial information for taking reasonable infection control measures in the future. We demonstrate agent-base…
View article: Full‐length plasma skeletal muscle myosin isoform deficiency is associated with coagulopathy in acutely injured patients
Full‐length plasma skeletal muscle myosin isoform deficiency is associated with coagulopathy in acutely injured patients Open
View article: Skeletal muscle myosin promotes coagulation by binding factor XI via its A3 domain and enhancing thrombin-induced factor XI activation
Skeletal muscle myosin promotes coagulation by binding factor XI via its A3 domain and enhancing thrombin-induced factor XI activation Open
View article: Corrosion Behavior of Carbon Steel Coated with a Zinc-Rich Paint Containing Aluminum Sulfate and Barium Oxide under Wet and Dry Cyclic Conditions
Corrosion Behavior of Carbon Steel Coated with a Zinc-Rich Paint Containing Aluminum Sulfate and Barium Oxide under Wet and Dry Cyclic Conditions Open
金属化合物としてAl2(SO4)3とBaOを添加したジンクリッチペイントを塗布した炭素鋼を乾湿繰り返し腐食試験に供した.金属化合物無添加の場合に認められた白色腐食生成物と鉄さびの生成は,金属化合物の添加により抑制された.また,金属化合物添加により腐食電流密度が大幅に低下した.金属化合物を添加した塗膜中にはAlを含んだSimonkolleiteと微細なBaSO4が形成され,ジンクリッチペイント塗膜の防食性を高めたと考えられる.
View article: Structure of Corrosion Product Formed on Carbon Steel Covered with NiSO<sub>4</sub>-Added Resin Coating under Sulfuric Acid Mist Environment Containing Chloride
Structure of Corrosion Product Formed on Carbon Steel Covered with NiSO<sub>4</sub>-Added Resin Coating under Sulfuric Acid Mist Environment Containing Chloride Open
Corrosion resistance of carbon steel covered with resin coating containing nickel sulfate has been evaluated under chloride and sulfuric acid mist environment. The structure of corrosion products formed on steel surface was investigated by…
View article: Handbook of Systems Sciences
Handbook of Systems Sciences Open
Applied systems thinking has evolved since the 1950s through three paradigmatic waves. Authors in the first wave regarded systems as real-world entities, and systems models as representations of reality, so objectivity was important. In co…
View article: Procoagulant activities of skeletal muscle and cardiac myosins require both myosin protein and myosin-associated anionic phospholipids
Procoagulant activities of skeletal muscle and cardiac myosins require both myosin protein and myosin-associated anionic phospholipids Open
View article: Skeletal muscle myosin and cardiac myosin attenuate heparin's antithrombin‐dependent anticoagulant activity
Skeletal muscle myosin and cardiac myosin attenuate heparin's antithrombin‐dependent anticoagulant activity Open
View article: Novel blood coagulation molecules: Skeletal muscle myosin and cardiac myosin
Novel blood coagulation molecules: Skeletal muscle myosin and cardiac myosin Open
View article: Closed-mindedness and insulation in groupthink: their effects and the devil’s advocacy as a preventive measure
Closed-mindedness and insulation in groupthink: their effects and the devil’s advocacy as a preventive measure Open
This paper’s purpose is to clarify groupthink phenomena and to assess the devil’s advocacy as a groupthink prevention measure. An agent-based model is presented to formalize group closed-mindedness and insulation in a group decision making…
View article: Structure of Corrosion Product Formed on Carbon Steel Covered with NiSO<sub>4</sub>-added Resin Coating under Sulfuric Acid Mist Environment Containing Chloride
Structure of Corrosion Product Formed on Carbon Steel Covered with NiSO<sub>4</sub>-added Resin Coating under Sulfuric Acid Mist Environment Containing Chloride Open
塩化物を含む硫酸ミスト環境において，NiSO4含有樹脂を被覆した炭素鋼の耐食性を評価した．形成した腐食生成物の構造を解明するため，放射光を用いたXRDおよびXAFS解析を実施した．NiSO4により，ゲーサイトおよびアカガネアイトの形成が促進された．このアカガネアイトは正方晶系のβ-FeOOHではなく，Niを含有した単斜晶系のアカガネアイトであると考えられる．
View article: Novel exomic rare variants associated with venous thrombosis
Novel exomic rare variants associated with venous thrombosis Open
Summary Exomic rare variant polymorphisms ( c . 300 000) were analysed in the Scripps Venous Thrombosis (VTE) registry (subjects aged <55 years). Besides coagulation factor V ( F5 ) single nucleotide polymorphisms (SNPs), family with seque…
View article: Cardiac Myosin Promotes Thrombin Generation and Coagulation In Vitro and In Vivo
Cardiac Myosin Promotes Thrombin Generation and Coagulation In Vitro and In Vivo Open
Objective: Cardiac myosin (CM) is structurally similar to skeletal muscle myosin, which has procoagulant activity. Here, we evaluated CM’s ex vivo, in vivo, and in vitro activities related to hemostasis and thrombosis. Approach and Results…
View article: Plasma skeletal muscle myosin phenotypes identified by immunoblotting are associated with pulmonary embolism occurrence in young adults
Plasma skeletal muscle myosin phenotypes identified by immunoblotting are associated with pulmonary embolism occurrence in young adults Open
View article: Striated muscle myosin and blood coagulation
Striated muscle myosin and blood coagulation Open
View article: Serum amyloid A4 is a procoagulant apolipoprotein that it is elevated in venous thrombosis patients
Serum amyloid A4 is a procoagulant apolipoprotein that it is elevated in venous thrombosis patients Open
View article: Activated protein C anticoagulant activity is enhanced by skeletal muscle myosin
Activated protein C anticoagulant activity is enhanced by skeletal muscle myosin Open
View article: Care providers, access to care, and the Long-term Care Nursing Insurance in China: An agent-based simulation
Care providers, access to care, and the Long-term Care Nursing Insurance in China: An agent-based simulation Open
View article: Hard X-ray Photoelectron Spectroscopy Analysis of Surface Chemistry of Spray Pyrolyzed LiNi<sub>0.5</sub>Co<sub>0.2</sub>Mn<sub>0.3</sub>O<sub>2</sub> Positive Electrode Coated with Lithium Boron Oxide
Hard X-ray Photoelectron Spectroscopy Analysis of Surface Chemistry of Spray Pyrolyzed LiNi<sub>0.5</sub>Co<sub>0.2</sub>Mn<sub>0.3</sub>O<sub>2</sub> Positive Electrode Coated with Lithium Boron Oxide Open
It is known that the deterioration of LiNi 0.5 Co 0.2 Mn 0.3 O 2 is suppressed by inhibiting direct contact between the cathodes and the electrolyte by surface coating.In order to evaluate the influence of the electrode/electrolyte interfa…
View article: Molecular interaction site on procoagulant myosin for factor Xa–dependent prothrombin activation
Molecular interaction site on procoagulant myosin for factor Xa–dependent prothrombin activation Open
Skeletal muscle myosin has potent procoagulant activity that is based on its ability to enhance thrombin generation due to binding coagulation factors Xa and Va and accelerating prothrombin activation. A well-studied myosin inhibitor that …
View article: Cardiac and Skeletal Muscle Myosin Exert Procoagulant Effects
Cardiac and Skeletal Muscle Myosin Exert Procoagulant Effects Open
Introduction: Trauma-induced coagulopathy (TIC) and the tissue injury-provoked procoagulant profile are prevalent in severely injured patients, but their mechanisms remain unclear. Myosin, exposed by or released from tissue injury, may pla…