Explanipedia

Efficacy of functional alignment in total knee arthroplasty in restoring in vivo cruciate ligament forces and knee kinematics compared with mechanical alignment Open

Kenichi Kono, Hiroshi Inui, Tomofumi Kage, Takaharu Yamazaki, Shuji Taketomi , et al. · 2025

Purpose The impact of coronal alignment on cruciate ligament forces in bicruciate‐retaining total knee arthroplasty (TKA) remains unclear. We aimed to clarify in vivo cruciate ligament forces and knee kinematics among mechanically aligned …

Clinical results of reverse shoulder arthroplasty after failed arthroscopic rotator cuff repair compared to primary cases: a case–control study Open

Noriaki Shimada, Junichi Inoue, Ryota Takei, Kazuo Saita, Hiroshi Inui · 2025

Intraoperative kinematics of the bicruciate retaining TKA using functional alignment and their influence on the clinical outcomes Open

Hiroshi Inui, Ryota Yamagami, Kenichi Kono, Kohei Kawaguchi, Haruhiko Nakamura , et al. · 2025

Background Our surgical team has been performing bicruciate-retaining total knee arthroplasty (BCR-TKAs) with functional alignment (FA). This study aimed to investigate knee kinematics before and after FA BCR-TKA, as well as the influence …

Anatomical and component rotational mismatches negatively affect postoperative outcomes in total knee arthroplasty Open

Kohei Kawaguchi, Ryota Yamagami, Kenichi Kono, Junfeng Zhang, Shuji Taketomi , et al. · 2025

Purpose Anatomical rotational mismatch (ARM) refers to postoperative malrotation between the femur and tibia, and component rotational mismatch (CRM) refers to malrotation between the femoral and tibial components in total knee arthroplast…

Nrf2-and p53-inducible REDD2/DDiT4L/Rtp801L confers pancreatic β-cell dysfunction, leading to glucose intolerance in high-fat diet-fed mice Open

Yukiho Yamada, Norimoto URAKAWA, H Tamiya, S Sakamoto, Hiroki Takahashi , et al. · 2025

Pancreatic β-cells play a critical role in glucose homeostasis by secreting insulin. Chronic oxidative stress causes β-cell dysfunction, including β-cell loss; however, the underlying mechanisms remain unclear. Here, we demonstrate the cri…

CD34hi subset of synovial fibroblasts contributes to fibrotic phenotype of human knee osteoarthritis Open

Junya Miyahara, Yasunori Omata, Ryota Chijimatsu, Hiroyuki Okada, Hisatoshi Ishikura , et al. · 2025

Osteoarthritis (OA) shows various clinical manifestations depending on the status of its joint components. We aimed to identify the synovial cell subsets responsible for OA pathophysiology by comprehensive analyses of human synovium sample…

Temporal changes of tibial eminence after bi-cruciate retaining total knee arthroplasty Open

Hiroshi Inui, Ryota Yamagami, Kenichi Kono, Kohei Kawaguchi, Kazuo Saita , et al. · 2025

Influence of Axial Rotation Between the Femoral Neck and Ankle Joint on Kinematics in Normal Knees: A Cross-Sectional Study Open

Kenichi Kono, Shuji Taketomi, Takaharu Yamazaki, Tomofumi Kage, Masashi Tamaki , et al. · 2025

Background: The effect of axial rotation between the femoral neck and ankle joint (total rotation [TR]) on normal knees is unknown. Therefore, this study aimed to investigate the TR effect on normal knee kinematics. Methods: Volunteers wer…

Clinical outcomes and biomechanics in bicruciate‐retaining total knee arthroplasty Open

Kenichi Kono, Tomofumi Kage, Takaharu Yamazaki, Shuji Taketomi, Ryota Yamagami , et al. · 2025

Purpose To clarify the influence of biomechanics on post‐operative clinical outcomes in bicruciate‐retaining total knee arthroplasty (BCR‐TKA). Methods Severe medial osteoarthritis who underwent BCR‐TKA were examined. Each patient was aske…

In vivo kinematic analysis of failure cases after nonanatomical anterior cruciate ligament reconstruction: a preliminary study Open

Tomofumi Kage, Shuji Taketomi, Tetsuya Tomita, Takaharu Yamazaki, Ryota Yamagami , et al. · 2024

Background Nonanatomical anterior cruciate ligament (ACL) reconstruction occasionally induces ACL failure without an evident injury episode, necessitating revision surgery. Although the in vivo kinematics of ACL deficiency before primary A…

Medial pivot total knee arthroplasty for valgus knees provides equivalent medial stability compared to that for varus knees: In vivo kinematic study Open

Tomofumi Kage, Kenichi Kono, Tetsuya Tomita, Takaharu Yamazaki, Shuji Taketomi , et al. · 2024

Purpose The efficacy of medial pivot total knee arthroplasty (MP TKA) in treating valgus knees that may cause medial instability is unknown. The purpose of this study was to investigate the in vivo kinematics of MP TKA for the valgus knees…

In vivo kinematic comparison of bi-cruciate retaining total knee arthroplasty between mechanical alignment and functional alignment methods Open

Tomofumi Kage, Kenichi Kono, Tetsuya Tomita, Takaharu Yamazaki, Shuji Taketomi , et al. · 2024

Method for defining the horizontal plane in fluoroscopic kinematic analysis Open

Takahiro Arakawa, Kenichi Kono, Tetsuya Tomita, Takaharu Yamazaki, Masashi Tamaki , et al. · 2024

Purpose: In vivo kinematics of skeletal joints and prostheses is affected by gravity; therefore, absolute tilt must be taken into account. However, current fluoroscopic kinematic analysis cannot measure the tilt. This study introduces and …

Insulin reduces endoplasmic reticulum stress‐induced apoptosis by decreasing mitochondrial hyperpolarization and caspase‐12 in <span>INS</span>‐1 pancreatic β‐cells Open

Nanako Murata, K. Nishimura, Naoki Harada, Tomoya Kitakaze, Eiji Yoshihara , et al. · 2024

Pancreatic β‐cell mass is a critical determinant of insulin secretion. Severe endoplasmic reticulum (ER) stress causes β‐cell apoptosis; however, the mechanisms of progression and suppression are not yet fully understood. Here, we report t…

Sitting Sideways Causes Different Femoral-Tibial Rotations in Each Knee Open

Kenichi Kono, Shoji Konda, Takaharu Yamazaki, Shuji Taketomi, Masashi Tamaki , et al. · 2024

Purpose According to a previous study, asymmetrical kneeling, such as sitting sideways, does not exhibit asymmetrical movements. Rotational analyses of each femur and tibia help explain why rotational knee kinematics while sitting sideways…

Intraoperative reliability of the tibial anteroposterior axis “Akagi's Line” in total knee arthroplasty Open

Kohei Kawaguchi, Ryota Yamagami, Kenichi Kono, Tomofumi Kage, Ryo Murakami , et al. · 2024

Purpose The tibial anatomical anteroposterior (AP) axis “Akagi's line” was originally defined on computed tomography (CT) in total knee arthroplasty (TKA); however, its intraoperative reproducibility remains unknown. This study aimed to ev…

Learning curve of minimally invasive anterolateral approach in supine position for total hip arthroplasty Open

Hiroshi Inui, Isao Nakasone, T. Kanazawa, Tetsu Yamashita, Yu Tanuma , et al. · 2024

Background: Total hip arthroplasty (THA) using minimally invasive anterolateral approach in the supine position (ALS) is reported to achieve good clinical outcomes including lower dislocation rates and early clinical recovery. However, min…

Mogrol stimulates G-protein-coupled bile acid receptor 1 (GPBAR1/TGR5) and insulin secretion from pancreatic β-cells and alleviates hyperglycemia in mice Open

Chisato Tanaka, Naoki Harada, Y. Teraoka, Hiroki Urushizaki, Yoh Shinmori , et al. · 2024

Target identification is a crucial step in elucidating the mechanisms by which functional food components exert their functions. Here, we identified the G-protein-coupled bile acid receptor 1 (GPBAR1, also known as TGR5) as a target of the…

In vivo three-dimensional kinematic comparison of normal knees between flexion and extension activities Open

Kenichi Kono, Takaharu Yamazaki, Shuji Taketomi, Hiroshi Inui, Sakae Tanaka , et al. · 2024

In Vivo Kinematic Analysis of Mobile-Bearing Unicompartmental Knee Arthroplasty during High Flexion Activities Open

Kenichi Kono, Takaharu Yamazaki, Masashi Tamaki, Hiroshi Inui, Sakae Tanaka , et al. · 2024

Mobile-bearing (MB) unicompartmental knee arthroplasty (UKA) has high conformity between the femoral articular surface and the meniscal bearing; therefore, the surface and subsurface contact stress is reduced. Additionally, the survival ra…

Short-term clinical results of bicruciate-retaining total knee arthroplasty using personalized alignment Open

Hiroshi Inui, Ryota Yamagami, Kenichi Kono, Kohei Kawaguchi, Tomofumi Kage , et al. · 2023

Postoperative quadriceps weakness and male sex are risk factors for patellofemoral articular cartilage lesions after anatomical anterior cruciate ligament reconstruction Open

Ryo Murakami, Shuji Taketomi, Ryota Yamagami, Kenichi Kono, Kohei Kawaguchi , et al. · 2023

Purpose Patellofemoral (PF) compartment cartilage lesions are a frequent problem after anterior cruciate ligament (ACL) reconstruction. This study aimed to determine the factors that influence PF cartilage lesions after anatomical ACL reco…

Short-term clinical results of bicruciate-retaining total knee arthroplasty using functional alignment Open

Hiroshi Inui, Ryota Yamagami, Kenichi Kono, Kohei Kawaguchi, Tomofumi Kage , et al. · 2023

Background Bicruciate-retaining (BCR) prosthesis has been introduced to recreate normal knee movement by preserving both the anterior and posterior cruciate ligaments. However, the use of BCR total knee arthroplasty (TKA) is still debatabl…

Sitting sideways causes different femoral–tibial rotations in each knee Open

Kenichi Kono, Shoji Konda, Takaharu Yamazaki, Shuji Taketomi, Masashi Tamaki , et al. · 2023

Background Asymmetrical kneeling motions, such as sitting sideways, do not require asymmetrical movements. Rotational analyses of each femur and tibia can help explain why rotational knee kinematics do not exhibit asymmetrical movement whi…

Chronological change of tibial eminence after bi-cruciate retaining total knee arthroplasty Open

Hiroshi Inui, Ryota Yamagami, Kenichi Kono, Kohei Kawaguchi, Kazuo Saita , et al. · 2023

Background Bicruciate-retaining (BCR) prostheses have been introduced to recreate normal knee movements by preserving both the anterior and posterior cruciate ligament. One of the surgical procedures essential to the success of BCR total k…

Issue Information ‐ Editorial Board and TOC Open

Caleb W. Grote, Matthew Mackay, Qinghua Lu, Xiangliang Liu, Anders R.L. Meyer , et al. · 2023

Risk factors for hamstring strain injury in male college American football players -a preliminary prospective cohort study- Open

Yuri Mizutani, Shuji Taketomi, Kohei Kawaguchi, Seira Takei, Ryota Yamagami , et al. · 2023

Background Given the frequency of hamstring strain injuries (HSI) among male college American football players, several studies have attempted to determine whether certain risk factors can predict their occurrence. However, no consensus on…

Changes in knee joint destruction patterns among patients with rheumatoid arthritis undergoing total knee arthroplasty in recent decades Open

Ryutaro Takeda, Takumi Matsumoto, Yasunori Omata, Hiroshi Inui, Shuji Taketomi , et al. · 2023

Midterm clinical results of bi-cruciate stabilized total knee arthroplasty compared with posterior stabilized total knee arthroplasty with single radius design Open

Hiroshi Inui, Ryota Yamagami, Kenichi Kono, Kohei Kawaguchi, Shuji Taketomi , et al. · 2023

Purpose: Attempts have been made to enhance knee prostheses design to improve clinical outcomes including bi-cruciate stabilized (BCS) TKA design and single-radius (SR) femoral component design. The complication rate of first generation BC…

Effect of component rotational alignment on femorotibial rotational alignment in total knee arthroplasty: comparison between mobile and fixed bearing Open

Kohei Kawaguchi, Hiroshi Inui, Ryota Yamagami, Kenichi Kono, Tomofumi Kage , et al. · 2023

Purpose: “Rotational self-alignment mechanism'' was designed for mobile-bearing total knee arthroplasty (MB TKA) to maintain a natural femorotibial rotational alignment independent of component rotational alignment. However, it is clinical…

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