Hiroshi Matsushima
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View article: Three-dimensional CT imaging in extensor tendons using deep learning reconstruction: Optimal dose and reconstruction parameters
Three-dimensional CT imaging in extensor tendons using deep learning reconstruction: Optimal dose and reconstruction parameters Open
The purpose of this study was to evaluate the optimal tube current and reconstruction parameters in extensor tendons 3-dimensional computed tomography (3D CT) using deep learning reconstruction, using iterative reconstruction as a referenc…
View article: 3D-Image-Guided Multi-Catheter Interstitial Brachytherapy for Bulky and High-Risk Stage IIB–IVB Cervical Cancer
3D-Image-Guided Multi-Catheter Interstitial Brachytherapy for Bulky and High-Risk Stage IIB–IVB Cervical Cancer Open
This study aimed to evaluate the efficacy and safety of computed tomography-magnetic resonance imaging (CT-MRI)-guided multi-catheter interstitial brachytherapy for patients with bulky (≥4 cm) and high-risk, stage IIB–IVB advanced cervical…
View article: Supplementary Material for: A Randomized Phase 2 Study of 5-Aminolevulinic Acid Hydrochloride and Sodium Ferrous Citrate for the Prevention of Nephrotoxicity Induced by Cisplatin-Based Chemotherapy of Lung Cancer
Supplementary Material for: A Randomized Phase 2 Study of 5-Aminolevulinic Acid Hydrochloride and Sodium Ferrous Citrate for the Prevention of Nephrotoxicity Induced by Cisplatin-Based Chemotherapy of Lung Cancer Open
Introduction: Cisplatin-based chemotherapy was established in the 1980s, and it has been improved by the development of a short hydration protocol in lung cancer therapy. However, cisplatin-based chemotherapy is still associated with renal…
View article: Protocol for a modified vaginal pipe for total laparoscopic hysterectomies: Experimental research
Protocol for a modified vaginal pipe for total laparoscopic hysterectomies: Experimental research Open
The protocol was approved by the institutional review boards. Written informed consent will be obtained from all patients before registration in accordance with the Declaration of Helsinki. Results of the study will be disseminated via pub…
View article: Treatment rationale and design of a phase I single-arm open trial of a modified vaginal pipe for use in total laparoscopic hysterectomies
Treatment rationale and design of a phase I single-arm open trial of a modified vaginal pipe for use in total laparoscopic hysterectomies Open
Background: The Vagi-Pipe® is a useful device for performing total laparoscopic hysterectomy. The conventional model of the Vagi-Pipe® is unable to grasp the uterus during colpotomy for recovery of the resected uterus. However, the modifie…
View article: Estrogen-related receptor α as a potential molecular target for endometrial cancer therapy
Estrogen-related receptor α as a potential molecular target for endometrial cancer therapy Open
Background: Estrogen-related receptor α (ERRα) is considered to be a potential molecular target against several cancer types. We previously demonstrated that ERRα knockdown regulated tumor progression in uterine endometrial cancer. The pur…
View article: Outcome of progestin therapy in patients with endometrial cancer recurrence
Outcome of progestin therapy in patients with endometrial cancer recurrence Open
Objective: The aim of this study was to elucidate the efficacy of progestin therapy in patients with endometrial cancer recurrence. Methods: Patients who received 200 mg/day of oral medroxyprogesterone acetate (MPA) therapy for endometrial…
View article: Passivation Behaviour of Anode in Copper Electrorefining Using Recycled Low-grade Copper Anode
Passivation Behaviour of Anode in Copper Electrorefining Using Recycled Low-grade Copper Anode Open
Cu electrolysis was performed using low-grade copper anode with purity 78.7 mass% at a anode current density of 200 A・m-2 in an unagitated sulfate solution containing 0.596 mol・dm-3 of Ni2+ ions as impurity at 60 ℃, and the structure of an…
View article: Anti-tumor effect of estrogen-related receptor alpha knockdown on uterine endometrial cancer
Anti-tumor effect of estrogen-related receptor alpha knockdown on uterine endometrial cancer Open
Estrogen-related receptor (ERR)α presents structural similarities with estrogen receptor (ER)α. However, it is an orphan receptor not binding to naturally occurring estrogens. This study was designed to investigate the role of ERRα in endo…
View article: Apocrine Adenocarcinoma of the Vulva: A Case Report and Review of the Literature
Apocrine Adenocarcinoma of the Vulva: A Case Report and Review of the Literature Open
Primary vulvar adenocarcinomas are very rare. We describe the rare case of primary vulvar apocrine adenocarcinoma, a histologically rare subtype of vulvar adenocarcinoma. A 57-year-old Japanese woman presented with an enlarging vulvar mass…
View article: Loss of AF-6/afadin induces cell invasion, suppresses the formation of glandular structures and might be a predictive marker of resistance to chemotherapy in endometrial cancer
Loss of AF-6/afadin induces cell invasion, suppresses the formation of glandular structures and might be a predictive marker of resistance to chemotherapy in endometrial cancer Open
AF-6/afadin regulates cell morphology and invasiveness. Invasive capability is partly regulated through the ERK and Src pathway. The inhibitors to these pathways might be molecular-targeted drugs which suppress myometrial invasion in endom…
View article: Dienogest reduces HSD17β1 expression and activity in endometriosis
Dienogest reduces HSD17β1 expression and activity in endometriosis Open
Endometriosis is an estrogen-dependent disease. Abnormally biosynthesized estrogens in endometriotic tissues induce the growth of the lesion and worsen endometriosis-associated pelvic pain. Dienogest (DNG), a selective progesterone recepto…