Hiroya Shiino
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View article: Oligomer-based functions of mitochondrial porin
Oligomer-based functions of mitochondrial porin Open
Porin, or the voltage-dependent anion channel (VDAC), is a primary β-barrel channel in the mitochondrial outer membrane. It transports small metabolites and ions through its β-barrel pore and plays key roles in apoptosis and inflammatory r…
View article: Dissociation of ERMES clusters plays a key role in attenuating the endoplasmic reticulum stress
Dissociation of ERMES clusters plays a key role in attenuating the endoplasmic reticulum stress Open
In yeast, ERMES, which mediates phospholipid transport between the ER and mitochondria, forms a limited number of oligomeric clusters at ER-mitochondria contact sites in a cell. Although the number of the ERMES clusters appears to be regul…
View article: Phosphatidylserine flux into mitochondria unveiled by organelle‐targeted <i>Escherichia coli</i> phosphatidylserine synthase PssA
Phosphatidylserine flux into mitochondria unveiled by organelle‐targeted <i>Escherichia coli</i> phosphatidylserine synthase PssA Open
Most phospholipids are synthesised in the endoplasmic reticulum and distributed to other cellular membranes. Although the vesicle transport contributes to the phospholipid distribution among the endomembrane system, exactly how phospholipi…
View article: Yeast transformation stress, together with loss of Pah1, phosphatidic acid phosphatase, leads to Ty1 retrotransposon insertion into the <i>INO4</i> gene
Yeast transformation stress, together with loss of Pah1, phosphatidic acid phosphatase, leads to Ty1 retrotransposon insertion into the <i>INO4</i> gene Open
Most phospholipids are synthesized via modification reactions of a simple phospholipid phosphatidic acid (PA). PA and its modified phospholipids travel between organelle membranes, for example, the endoplasmic reticulum (ER) and mitochondr…