Hiroyuki Sumikura
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View article: GENOME-WIDE ASSOCIATION STUDY IDENTIFIES CANDIDATE GENETIC POLYMORPHISMS ASSOCIATED WITH POSTOPERATIVE NAUSEA AND/OR VOMITING
GENOME-WIDE ASSOCIATION STUDY IDENTIFIES CANDIDATE GENETIC POLYMORPHISMS ASSOCIATED WITH POSTOPERATIVE NAUSEA AND/OR VOMITING Open
Background General anaesthesia is commonly conducted in surgeries for the treatment of cancer or other diseases. Whereas postoperative nausea and/or vomiting (PONV) is known as the most frequent side effect following anaesthesia, considera…
View article: Effect of <scp>A118G</scp> (rs1799971) single‐nucleotide polymorphism of the μ‐opioid receptor <i>OPRM1</i> gene on intraoperative remifentanil requirements in Japanese women undergoing laparoscopic gynecological surgery
Effect of <span>A118G</span> (rs1799971) single‐nucleotide polymorphism of the μ‐opioid receptor <i>OPRM1</i> gene on intraoperative remifentanil requirements in Japanese women undergoing laparoscopic gynecological surgery Open
Aim Abundant data are available on the effect of the A118G (rs1799971) single‐nucleotide polymorphism (SNP) of the μ‐opioid receptor OPRM1 gene on morphine and fentanyl requirements for pain control. However, data on the effect of this SNP…
View article: Genome-Wide Association Study Identifies Novel Candidate Variants Associated with Postoperative Nausea and Vomiting
Genome-Wide Association Study Identifies Novel Candidate Variants Associated with Postoperative Nausea and Vomiting Open
Considerable individual differences are widely observed in the incidence of postoperative nausea and vomiting (PONV). We conducted a genome-wide association study (GWAS) to identify potential candidate single-nucleotide polymorphisms (SNPs…
View article: Anesthesia outcomes of pregnant women with spinal diseases: a single-center case-series study
Anesthesia outcomes of pregnant women with spinal diseases: a single-center case-series study Open
Background Neuraxial anesthesia is widely used as the most effective and standard method in obstetric anesthesia. However, there is a concern that neuraxial anesthesia may be technically difficult or ineffective in pregnant women with spin…
View article: Association of chorioamnionitis with failed conversion of epidural labor analgesia to cesarean delivery anesthesia: A retrospective cohort study
Association of chorioamnionitis with failed conversion of epidural labor analgesia to cesarean delivery anesthesia: A retrospective cohort study Open
Aim This study aimed to examine the association between clinically diagnosed chorioamnionitis and failed conversion of epidural labor analgesia to cesarean delivery anesthesia. Methods This retrospective, single-center cohort study, conduc…
View article: Effects of rs958804 and rs7858836 single‐nucleotide polymorphisms of the <i>ASTN2</i> gene on pain‐related phenotypes in patients who underwent laparoscopic colectomy and mandibular sagittal split ramus osteotomy
Effects of rs958804 and rs7858836 single‐nucleotide polymorphisms of the <i>ASTN2</i> gene on pain‐related phenotypes in patients who underwent laparoscopic colectomy and mandibular sagittal split ramus osteotomy Open
Background Opioids are widely used as effective analgesics, but opioid sensitivity varies widely among individuals. The underlying genetic and nongenetic factors are not fully understood. Based on the results of our previous genome‐wide as…
View article: Additional file 1 of The value of the portable fibrinogen measuring device—a case report of severe postpartum hemorrhage with obstetric disseminated intravascular coagulation
Additional file 1 of The value of the portable fibrinogen measuring device—a case report of severe postpartum hemorrhage with obstetric disseminated intravascular coagulation Open
Additional file 1.
View article: Association of Chorioamnionitis With Failed Conversion of Epidural Labor Analgesia to Cesarean Delivery Anesthesia: a Retrospective Cohort Study
Association of Chorioamnionitis With Failed Conversion of Epidural Labor Analgesia to Cesarean Delivery Anesthesia: a Retrospective Cohort Study Open
Background: This study examined the association between clinically diagnosed chorioamnionitis and failed conversion of epidural labor analgesia to cesarean delivery anesthesia.Methods: This retrospective cohort study, conducted in a single…
View article: Changes in the Perinatal Medical System before and after the Obstetric Anesthesia Team Was Established at Juntendo Hospital
Changes in the Perinatal Medical System before and after the Obstetric Anesthesia Team Was Established at Juntendo Hospital Open
当院における産科麻酔チーム設立前後の周産期医療の変化は，予想以上に大きいものであり，医師のみならず助産師にも大きく影響したといえる．その変化は，症例数・産科医の技術・医療体制・カンファレンス・個々の意識という，施設の医療レベルを支える重要なものであった．何よりも，産科と麻酔科の両科の立場からの意見・情報を気軽に求めることが可能になった環境・意識の変化が，内科合併症も多い当院のハイリスク妊婦に対しても，安全な医療を提供できる一番の変化といえる．本稿では，その変化について具体的…
View article: Anesthetic management of urgent cesarean section
Anesthetic management of urgent cesarean section Open
The validity of the 30-minute cesarean section (CS) rule has been questioned. A new classification of the urgency of CS was introduced by the NICE in the United Kingdom and has received considerable attention in recent years. In the guidel…