Shoji Takeuchi
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View article: Shape‐Encoded Hydrogel Sensor Particles Enable Multiplex Odorant Detection Through Deep‐learning Classification
Shape‐Encoded Hydrogel Sensor Particles Enable Multiplex Odorant Detection Through Deep‐learning Classification Open
Simultaneous detection of multiple odorants is a major challenge in the development of portable, cell‐based biohybrid sensors, primarily due to the difficulty of distinguishing between different sensor cell types. Here, a strategy that enc…
View article: Cell-based multisensor array for detecting cancer biomarkers in human urine
Cell-based multisensor array for detecting cancer biomarkers in human urine Open
Detecting volatile urinary biomarkers offers a compelling strategy for noninvasive diagnosis of diseases such as cancer. Biohybrid sensors employing sensor cells that express olfactory receptors—with finely tuned molecular recognition capa…
View article: Nuclear Assembly in Giant Unilamellar Vesicles Encapsulating <i>Xenopus</i> Egg Extract
Nuclear Assembly in Giant Unilamellar Vesicles Encapsulating <i>Xenopus</i> Egg Extract Open
The reconstitution of a cell nucleus in a lipid bilayer‐enclosed synthetic cell makes great strides in bottom‐up synthetic biology. In this study, a method for assembling a nucleus in giant unilamellar vesicles (GUVs) is proposed. To induc…
View article: Effective Dissolution of a Gaseous Odorant in Liquid Using Gas Flow
Effective Dissolution of a Gaseous Odorant in Liquid Using Gas Flow Open
Olfactory receptors are known for their high specificity, sensitivity, and nanometer‐sized sensing element, making them ideal for in situ odorant sensor applications. However, one of the major limitations of these sensors is the requiremen…
View article: Nuclear assembly in giant unilamellar vesicles encapsulating<i>Xenopus</i>egg extract
Nuclear assembly in giant unilamellar vesicles encapsulating<i>Xenopus</i>egg extract Open
The reconstitution of a cell nucleus in a lipid bilayer-enclosed synthetic cell makes great strides in bottom-up synthetic biology. In this study, we propose a method for assembling a nucleus in giant unilamellar vesicles (GUVs). To induce…
View article: Back Cover, Volume 2, Number 3, July 2023
Back Cover, Volume 2, Number 3, July 2023 Open
Back Cover: The cover image is based on the Research Article Reproducible reformation of a bilayer lipid membrane using microair bubbles by Hashimoto et al. A microair bubble facilitates the self-assembly of an amphiphilic lipid monolayer …
View article: Reproducible reformation of a bilayer lipid membrane using microair bubbles
Reproducible reformation of a bilayer lipid membrane using microair bubbles Open
Planar bilayer lipid membranes (BLMs) are widely used as models for cell membranes in various applications, including drug discovery and biosensors. However, the nanometer‐thick bilayer structure, assembled through hydrophobic interactions…
View article: Highly sensitive VOC detectors using insect olfactory receptors reconstituted into lipid bilayers
Highly sensitive VOC detectors using insect olfactory receptors reconstituted into lipid bilayers Open
A highly sensitive odorant sensor was developed by using insect olfactory receptors reconstituted into a lipid bilayer membrane.
View article: A Lipid-Bilayer-On-A-Cup Device for Pumpless Sample Exchange
A Lipid-Bilayer-On-A-Cup Device for Pumpless Sample Exchange Open
Lipid-bilayer devices have been studied for on-site sensors in the fields of diagnosis, food and environmental monitoring, and safety/security inspection. In this paper, we propose a lipid-bilayer-on-a-cup device for serial sample measurem…
View article: Rapid Detection of Analyte using Nanopore Sensor under Solution Mixing
Rapid Detection of Analyte using Nanopore Sensor under Solution Mixing Open
Nanopore sensor attracts attention as a highly sensitive and selective detection mechanism of analytes at single molecule level. In previous studies, nanopore sensors were applied for detection of nucleic acids, organic molecules, and meta…
View article: Gas flow system for cell-based odorant sensor
Gas flow system for cell-based odorant sensor Open
We examined a gas-flow channel developed for cell-based odorant sensor for dissolution of odorant molecules into liquid phase. Cell-based sensors using insect olfactory receptors attract increasing attention as highly sensitive and selecti…