Hisayuki Kato
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View article: A single-center retrospective study of dabrafenib plus trametinib combination therapy in patients with BRAF V600E-positive thyroid cancer
A single-center retrospective study of dabrafenib plus trametinib combination therapy in patients with BRAF V600E-positive thyroid cancer Open
Background BRAF V600E mutation is a key oncogenic driver commonly found in papillary thyroid carcinoma (PTC) and anaplastic thyroid carcinoma (ATC). Dabrafenib plus trametinib combination therapy targeting this mutation has shown promising…
View article: A single-center retrospective study of dabrafenib plus trametinib combination therapy in patients with BRAF V600E-positive thyroid cancer
A single-center retrospective study of dabrafenib plus trametinib combination therapy in patients with BRAF V600E-positive thyroid cancer Open
Background: BRAF V600E mutation is a key oncogenic driver commonly found in papillary thyroid carcinoma (PTC) and anaplastic thyroid carcinoma (ATC). Dabrafenib plus trametinib combination therapy targeting this mutation has shown promisin…
View article: Retrospective study of definitive therapy for head and neck mucosal melanoma: The RESUME study
Retrospective study of definitive therapy for head and neck mucosal melanoma: The RESUME study Open
Background: Head and neck mucosal melanoma (HNMM) is a rare melanoma. Surgery and radiotherapy (RT) are commonly used; however, their effectiveness remains unclear. In addition, the role of immune checkpoint inhibitors (ICIs) in improving …
View article: A case of tracheotomy using the Ex Utero Intrapartum Treatment (EXIT) procedure in cooperation with multiple professions.
A case of tracheotomy using the Ex Utero Intrapartum Treatment (EXIT) procedure in cooperation with multiple professions. Open
In this study, we report a case of tracheotomy using the ex utero intrapartum treatment (EXIT) procedure in a fetus that was pointed out as having bilateral giant cervical cysts at prenatal diagnosis and whose postnatal airway occlusion wa…
View article: Objective assessment of nasal obstruction.
Objective assessment of nasal obstruction. Open
There are many methods and types of equipment for measuring the nasal airway, but there is no consensus regarding the results of various clinical studies on nasal obstruction. In this review, we discuss the two major methods of objectively…
View article: Current Status of Transoral Surgery for Patients With Early-Stage Pharyngeal and Laryngeal Cancers in Japan
Current Status of Transoral Surgery for Patients With Early-Stage Pharyngeal and Laryngeal Cancers in Japan Open
As the laryngopharynx is closely related to swallowing, speech, and phonation, it is necessary to consider not only disease control but also a minimally invasive approach for the treatment of laryngopharyngeal cancer. Transoral surgery has…
View article: IL13 May Play an Important Role in Developing Eosinophilic Chronic Rhinosinusitis and Eosinophilic Otitis Media with Severe Asthma
IL13 May Play an Important Role in Developing Eosinophilic Chronic Rhinosinusitis and Eosinophilic Otitis Media with Severe Asthma Open
A woman in her 50s was a super responder to benralizumab administered for the treatment of severe bronchial asthma (BA) with eosinophilic chronic rhinosinusitis with nasal polyp (ECRS) and eosinophilic otitis media (EOM). She exhibited the…
View article: Laryngeal allergy.
Laryngeal allergy. Open
Many patients with allergic rhinitis have accompanying laryngeal symptoms such as persistent cough and/or globus. Chronic laryngeal allergy is suspected to be an important cause of these laryngeal symptoms. We have been working toward esta…
View article: Optimization of therapeutic strategy for p16‐positive oropharyngeal squamous cell carcinoma: Multi‐institutional observational study based on the national Head and Neck Cancer Registry of Japan
Optimization of therapeutic strategy for p16‐positive oropharyngeal squamous cell carcinoma: Multi‐institutional observational study based on the national Head and Neck Cancer Registry of Japan Open
Background Although the American Joint Committee on Cancer TNM classification has been amended to include human papillomavirus (HPV)–related oropharyngeal squamous cell carcinoma (OPSCC) as an independent entity, to the authors' knowledge …
View article: Assessing nasal resistance in Japanese children by active anterior rhinomanometry
Assessing nasal resistance in Japanese children by active anterior rhinomanometry Open
Objectives: The mean bilateral nasal resistance in normal Japanese adults is 0.25±0.12 Pa/cm3/s, but this value in children remains unknown. This study aimed to determine the mean nasal resistance values in Japanese children. Methods: We m…
View article: A Case of Pharyngeal/Cervical Trauma Due to an Epileptic Attack during Brushing of the Teeth
A Case of Pharyngeal/Cervical Trauma Due to an Epileptic Attack during Brushing of the Teeth Open
Herein, we report a case of pharyngeal/cervical trauma sustained due to an epileptic attack that developed while the patient was brushing her teeth. The patient was a 20-year-old woman with schizophrenia and epileptic psychosis, who was ho…
View article: A Case of Papillary Carcinoma Arising from the Thyroglossal Duct
A Case of Papillary Carcinoma Arising from the Thyroglossal Duct Open
We report a case of papillary carcinoma arising from the thyroglossal duct. The patient was a 53-year-old woman who presented with an anterior neck mass. CT revealed a relatively well-delineated tumor in front of the hyoid bone, with minut…
View article: Correspondence between anatomical locations and points on the area–distance curve of acoustic rhinometry in an artificial model of a 5-year-old Japanese child
Correspondence between anatomical locations and points on the area–distance curve of acoustic rhinometry in an artificial model of a 5-year-old Japanese child Open
Determining the correspondence between points on the area–distance curve derived from acoustic rhinometry and the anatomical landmarks in the nasal and nasopharyngeal airway is important for the clinical evaluation of obstructive sleep apn…
View article: Surgical removal of hearing aid ear mold impression material from the middle ear: a report of two cases
Surgical removal of hearing aid ear mold impression material from the middle ear: a report of two cases Open
A hearing aid effectively improves the quality of life of hard-of-hearing people, but complications after obtaining an ear mold to facilitate fitting the hearing aid have been reported. We treated two patients in whom we surgically removed…
View article: A Case of Bronchial Foreign Body Lodged over a Long Term
A Case of Bronchial Foreign Body Lodged over a Long Term Open
今回われわれは，長期間介在した気管支異物の1例を報告した。症例は1歳4カ月の男児で，主訴は長期間持続する咳嗽であり，前医で肺炎と診断されて治療を受けていたが，治癒しなかった。4カ月後に胸部CTで気管支異物と診断された。気管支鏡で異物を摘出した。異物はセロハンテープであった。気管支異物の診断が遅れた理由は，X線透過性異物であったことと初診医が気管支異物を疑わなかったことと考えられた。
View article: Oropharyngeal Cancer and HPV
Oropharyngeal Cancer and HPV Open
At present, there are no high-impact biomarkers for deciding the course of treatment in patients with head and neck cancer. While smoking and alcohol abuse are among the most common risk factors for head and neck cancer, in the last decade…