Hitoshi Morikawa
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View article: Isradipine Enhancement of Virtual Reality Cue Exposure Therapy is Effective for Individuals with Higher Baseline Cue-Induced Craving
Isradipine Enhancement of Virtual Reality Cue Exposure Therapy is Effective for Individuals with Higher Baseline Cue-Induced Craving Open
Background: Evidence based treatments for smoking cessation have high relapse rates. Targeting cue-induced craving, a strong predictor of relapse, may be critical to promoting sustained abstinence. We previously found that isradipine, an F…
View article: ANALYTICAL DISCUSSION ON APPLICABILITY OF FREQUENCY DOMAIN DECOMPOSITION METHOD TO SYSTEMS EXCITED BY AN IMPULSE FORCE
ANALYTICAL DISCUSSION ON APPLICABILITY OF FREQUENCY DOMAIN DECOMPOSITION METHOD TO SYSTEMS EXCITED BY AN IMPULSE FORCE Open
This paper focuses on the use of vibration measurements for the purpose of cost-effective performance evaluation for the safety management and maintenance of Japan’s social infrastructure like bridges. Since modal properties are often used…
View article: Isradipine augmentation of virtual reality cue exposure therapy for tobacco craving: a triple-blind randomized controlled trial
Isradipine augmentation of virtual reality cue exposure therapy for tobacco craving: a triple-blind randomized controlled trial Open
Preclinical research with rodents suggests that the L-type calcium channel blocker isradipine can enhance long-term extinction of conditioned place preference for addictive substances when it is administered in conjunction with extinction …
View article: Isradipine augmentation of virtual reality cue exposure therapy for tobacco craving: a triple-blind randomized controlled trial
Isradipine augmentation of virtual reality cue exposure therapy for tobacco craving: a triple-blind randomized controlled trial Open
Preclinical research with rodents suggests that the L-type calcium channel blocker isradipine can enhance long-term extinction of conditioned place preference for addictive substances when it is administered in conjunction with extinction …
View article: Method for estimating azimuthal intensity distribution of microtremors using simple arrays
Method for estimating azimuthal intensity distribution of microtremors using simple arrays Open
SUMMARY In this paper, a method is proposed for estimating the intensity distribution of microtremors for the arrival direction, from simultaneous observations of vertical motion, using an array of simple geometry consisting of only three …
View article: Estimation of phase velocity using array observation of microtremors with arbitrary shape
Estimation of phase velocity using array observation of microtremors with arbitrary shape Open
To estimate the phase velocity using the array observations of microtremors, some algorithms for the estimation include constraints on the array shape, such as equilateral triangles or the placement of receivers on a circle, in order to re…
View article: An Energy-based Overset Finite Element Method for Pseudo-static Structural Analysis
An Energy-based Overset Finite Element Method for Pseudo-static Structural Analysis Open
This paper addresses a simple energy-based overset finite element method (EbO-FEM) to solve pseudo-static deformation problems consisting of overlapped meshes based on the domain composition method (DCM). This scheme is a non-iterative equ…
View article: Non-destructive high-throughput measurement of elastic-viscous properties of maize using a novel ultra-micro sensor array and numerical validation
Non-destructive high-throughput measurement of elastic-viscous properties of maize using a novel ultra-micro sensor array and numerical validation Open
Maize is the world's most produced cereal crop, and the selection of maize cultivars with a high stem elastic modulus is an effective method to prevent cereal crop lodging. We developed an ultra-compact sensor array inspired by earthquake …
View article: Applications of isradipine in human addiction studies: A systematic literature review.
Applications of isradipine in human addiction studies: A systematic literature review. Open
Given the personal and public health burden of addictive disorders, innovative approaches to treatment are sorely needed. This systematic review examined the use of the pharmacological agent isradipine in the context of potential applicati…
View article: Effect of Platelet-Rich Plasma on Autologous Chondrocyte Implantation for Chondral Defects: Results Using an In Vivo Rabbit Model
Effect of Platelet-Rich Plasma on Autologous Chondrocyte Implantation for Chondral Defects: Results Using an In Vivo Rabbit Model Open
Background: Articular cartilage repair remains challenging despite the availability of techniques, including autologous chondrocyte implantation (ACI) for repairing large cartilage defects. Platelet-rich plasma (PRP) therapy, a novel thera…
View article: Decision letter: Temporal derivative computation in the dorsal raphe network revealed by an experimentally driven augmented integrate-and-fire modeling framework
Decision letter: Temporal derivative computation in the dorsal raphe network revealed by an experimentally driven augmented integrate-and-fire modeling framework Open
Article Figures and data Abstract Editor's evaluation Introduction Results Discussion Materials and methods Appendix 1 Data availability References Decision letter Author response Article and author information Metrics Abstract By means of…
View article: ESTIMATION METHOD FOR THE SHAPE OF ENGINEERING BEDROCK USING THE VERTICAL FOURIER SPECTRUM BY MICROTREMOR OBSERVATIONS
ESTIMATION METHOD FOR THE SHAPE OF ENGINEERING BEDROCK USING THE VERTICAL FOURIER SPECTRUM BY MICROTREMOR OBSERVATIONS Open
工学的基盤が傾斜する地点では，水平成層地点と比較して地震動が局所的に増幅する可能性がある．よって，例えば，鉄道構造物の耐震設計では，工学的基盤の傾斜が1:10以上の地点で地盤不整形性による地盤増幅の影響を考慮している．不整形性はボーリング調査結果から判断するが，現状では調査箇所間の変動を補間で推測する．線状に建設される鉄道・道路構造物は地点ごとに地盤構造が大きく変動し，調査を補間するだけでは不整形性を見落とす可能性がある．そこで，常時微動観測とボーリング調査結果を併用した工…
View article: Simulation of wooden house collapse prediction in a whole city using the ASI-Gauss Code
Simulation of wooden house collapse prediction in a whole city using the ASI-Gauss Code Open
2011 年東北地方太平洋沖地震・津波,および 2016 年熊本地震では多数の木造家屋が倒壊した.倒壊家屋による大量の瓦礫は,道路を閉塞することで即時避難の妨げとなるだけでなく,撤去作業等に時間・コストがかかり復旧復興に遅れを生じさせるなどの要因となった.たとえば,東海・東南海地方において,同規模以上の地震・津波被害が生じる危険性が高いことが危惧されており,巨大地震時に発生しうる瓦礫の総量と拡散状況を事前評価し,災害後の非常事態に備えた復旧計画を予め立てておくことなどの災害…
View article: New insights on neurobiological mechanisms underlying alcohol addiction
New insights on neurobiological mechanisms underlying alcohol addiction Open
Alcohol dependence/addiction is mediated by complex neural mechanisms that involve multiple brain circuits and neuroadaptive changes in a variety of neurotransmitter and neuropeptide systems. Although recent studies have provided substanti…
View article: Isradipine enhancement of virtual reality cue exposure for smoking cessation: Rationale and study protocol for a double-blind randomized controlled trial
Isradipine enhancement of virtual reality cue exposure for smoking cessation: Rationale and study protocol for a double-blind randomized controlled trial Open
Cigarette smoking remains a leading cause of preventable death in the United States, contributing to over 480,000 deaths each year. Although significant strides have been made in the development of effective smoking cessation treatments, m…
View article: A METHOD TO IDENTIFY MODAL PROPERTIES OF SMALL-SCALED SEDIMENTARY BASIN
A METHOD TO IDENTIFY MODAL PROPERTIES OF SMALL-SCALED SEDIMENTARY BASIN Open
堆積盆地や埋積谷のような不整形地盤ではその基盤形状を反映した堆積層の振動モードが形成されることが知られている．このことは観測記録等から堆積層の振動モードを同定できればその基盤形状をも推定できる可能性を示唆している．しかし，小規模な埋積谷では狭い周波数帯に振動モードが多数含まれる上ノイズも混在するため，モード同定そのものが難しいことが予想される．本研究では小規模な埋積谷の振動モード特性同定に関する基礎研究として，詳細な工学的基盤形状が既知の埋積谷を対象に多点常時微動観測を行い…
View article: AN EXPERIMENTAL STUDY FOR APPLICATION OF ACCELEROMETER MADE OF QUARTZ OSCILLATOR TO MICROTREMOR SURVEY
AN EXPERIMENTAL STUDY FOR APPLICATION OF ACCELEROMETER MADE OF QUARTZ OSCILLATOR TO MICROTREMOR SURVEY Open
水晶振動子をセンサとして採用した加速度計(本稿では水晶加速度計と呼ぶ)は振り子の動きを電気信号に変換して記録する従来型の加速度計と全く異なる動作原理に基づくセンサである．水晶加速度計はその動作原理から理論的には小型のセンサであっても高い感度と精度が期待できる．そのため，観測システムに対して高感度，低ノイズ，小型，軽量，低消費電力といった相反する性能が要求される微動探査において水晶加速度計は高い親和性を有する．本稿では実際に想定される運用環境のもとでの観測を通して水晶加速度計…
View article: A point-estimate based method for soil amplification estimation using high resolution model under uncertainty of stratum boundary geometry
A point-estimate based method for soil amplification estimation using high resolution model under uncertainty of stratum boundary geometry Open
This study provides a practical technique for stochastically estimating soil amplification under uncertainty of the geometry of stratum boundary. To evaluate the possible values of the non-linear soil response under ambiguity, a nonlinear …
View article: A Corticotropin Releasing Factor Network in the Extended Amygdala for Anxiety
A Corticotropin Releasing Factor Network in the Extended Amygdala for Anxiety Open
The central amygdala (CeA) is important for fear responses to discrete cues. Recent findings indicate that the CeA also contributes to states of sustained apprehension that characterize anxiety, although little is known about the neural ci…