Hiyoung Kim
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View article: Anti-Obesity Effects of Acid-Processed Citrus reticulata Blanco Peel Extract Enriched in Highly Bioactive Polymethoxyflavones: Inhibition of 3T3-L1 Adipocyte Differentiation and Therapeutic Efficacy in ob/ob Mice
Anti-Obesity Effects of Acid-Processed Citrus reticulata Blanco Peel Extract Enriched in Highly Bioactive Polymethoxyflavones: Inhibition of 3T3-L1 Adipocyte Differentiation and Therapeutic Efficacy in ob/ob Mice Open
Background/Objectives: Chronic diseases linked to obesity represent a major global health challenge. Although pharmaceutical treatments show efficacy, their use is often limited by side effects. Methods: This study investigated the anti-ob…
View article: Diversity and composition of sponge-associated microbiomes from Korean sponges revealed by full-length 16S rRNA analysis
Diversity and composition of sponge-associated microbiomes from Korean sponges revealed by full-length 16S rRNA analysis Open
Marine sponges host diverse and specialized microbial communities that serve essential functions in nutrient cycling, ecosystem stability, and biotechnological applications. This study investigates the diversity and composition of sponge-a…
View article: Immunoenhancing Effects of Jeju Agastache rugosa Extracts on NK Cell Activity and Lymphocyte Proliferation in Cyclophosphamide-Induced Immunosuppression
Immunoenhancing Effects of Jeju Agastache rugosa Extracts on NK Cell Activity and Lymphocyte Proliferation in Cyclophosphamide-Induced Immunosuppression Open
Background/objectives: This study evaluated the immunoenhancing effects of Agastache rugosa extract in a cyclophosphamide-induced immunosuppressed mouse model. Methods: Jeju A. rugosa was processed via hot water extraction and 20% ethanol …
View article: Metagenomic insights and biosynthetic potential of <i>Candidatus</i> Entotheonella symbiont associated with <i>Halichondria</i> marine sponges
Metagenomic insights and biosynthetic potential of <i>Candidatus</i> Entotheonella symbiont associated with <i>Halichondria</i> marine sponges Open
Korea, being surrounded by the sea, provides a rich habitat for marine sponges, which have been a prolific source of bioactive natural products. Although a diverse array of structurally novel natural products has been isolated from Korean …
View article: Ameliorative Effects of Korean-Red-Ginseng-Derived Polysaccharide on Antibiotic-Associated Diarrhea
Ameliorative Effects of Korean-Red-Ginseng-Derived Polysaccharide on Antibiotic-Associated Diarrhea Open
This study evaluated the ameliorative effects of Korean-red-ginseng-derived polysaccharide (KRG-P) on antibiotic-associated diarrhea (AAD) induced by administering lincomycin in mice. Changes of intestinal barrier proteins, the intestinal …
View article: Development and Validation of Quantitative Analysis Method for Phenanthrenes in Peels of the <i>Dioscorea</i> Genus
Development and Validation of Quantitative Analysis Method for Phenanthrenes in Peels of the <i>Dioscorea</i> Genus Open
Phenanthrenes are bioactive phenolic compounds found in genus Dioscorea, in which they are distributed more in peel than in flesh. Recent studies on phenanthrenes from Dioscorea sp. peels have revealed the potential for valua…
View article: A Medicinal Halophyte Ipomoea pes-caprae (Linn.) R. Br.: A Review of Its Botany, Traditional Uses, Phytochemistry, and Bioactivity
A Medicinal Halophyte Ipomoea pes-caprae (Linn.) R. Br.: A Review of Its Botany, Traditional Uses, Phytochemistry, and Bioactivity Open
Ipomoea pes-caprae (Linn.) R. Br. (Convolvulaceae) is a halophytic plant that favorably grows in tropical and subtropical countries in Asia, America, Africa, and Australia. Even though this plant is considered a pan-tropical plant, I. pes-…
View article: Saccharobisindole, Neoasterric Methyl Ester, and 7-Chloro-4(1H)-quinolone: Three New Compounds Isolated from the Marine Bacterium Saccharomonospora sp.
Saccharobisindole, Neoasterric Methyl Ester, and 7-Chloro-4(1H)-quinolone: Three New Compounds Isolated from the Marine Bacterium Saccharomonospora sp. Open
Analysis of the chemical components from the culture broth of the marine bacterium Saccharomonospora sp. CNQ-490 has yielded three novel compounds: saccharobisindole (1), neoasterric methyl ester (2), and 7-chloro-4(1H)-quinolone (3), in a…
View article: Antibacterial Bicyclic Fatty Acids from a Korean Colonial Tunicate Didemnum sp.
Antibacterial Bicyclic Fatty Acids from a Korean Colonial Tunicate Didemnum sp. Open
Five new bicyclic carboxylic acids were obtained by antibacterial activity-guided isolation from a Korean colonial tunicate Didemnum sp. Their structures were elucidated by the interpretation of NMR, MS and CD spectroscopic data. They all …
View article: Comparative Genomics Reveals a Remarkable Biosynthetic Potential of the <i>Streptomyces</i> Phylogenetic Lineage Associated with Rugose-Ornamented Spores
Comparative Genomics Reveals a Remarkable Biosynthetic Potential of the <i>Streptomyces</i> Phylogenetic Lineage Associated with Rugose-Ornamented Spores Open
It is now well recognized that members of the genus Streptomyces still harbor a large number of cryptic BGCs in their genomes, which are mostly silent under laboratory culture conditions. Activation of transcriptionally silent BGCs is tech…
View article: Molecular identification of Ergalatax contracta from Yeongdo island, Korea
Molecular identification of Ergalatax contracta from Yeongdo island, Korea Open
The current study reports the cytochrome oxidase subunit 1 sequence of Gastropoda Ergalatax contracta from Busan, Korea. Four specimens were collected and extracted to obtain genomic DNA for the sequencing analysis. This is the first E. co…
View article: The Halicylindramides, Farnesoid X Receptor Antagonizing Depsipeptides from a <i>Petrosia</i> sp. Marine Sponge Collected in Korea
The Halicylindramides, Farnesoid X Receptor Antagonizing Depsipeptides from a <i>Petrosia</i> sp. Marine Sponge Collected in Korea Open
Three new structurally related depsipeptides, halicylindramides F-H (1-3), and two known halicylindramides were isolated from a Petrosia sp. marine sponge collected off the shore of Youngdeok-Gun, East Sea, Republic of Korea. Their planar …
View article: Acredinones A and B, Voltage-Dependent Potassium Channel Inhibitors from the Sponge-Derived Fungus <i>Acremonium</i> sp. F9A015
Acredinones A and B, Voltage-Dependent Potassium Channel Inhibitors from the Sponge-Derived Fungus <i>Acremonium</i> sp. F9A015 Open
Two new benzophenones, acredinones A (1) and B (2), were isolated from a marine-sponge-associated Acremonium sp. fungus. Their chemical structures were elucidated on the interpretation of spectroscopic data. The structure of 1 was confirme…