Hsiao‐Lin Hwa
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View article: Association between childhood polyvictimization, telomere length, and post‐traumatic stress disorder
Association between childhood polyvictimization, telomere length, and post‐traumatic stress disorder Open
Background Child maltreatment is related to adverse psychosocial outcomes and may be associated with telomere erosion. Longitudinal research on mental health problems and telomere length (TL) in victimized children in Asian societies is sc…
View article: Endothelial progenitor cell-derived conditioned medium mitigates chronic cerebral ischemic injury through macrophage migration inhibitory factor-activated AKT pathway
Endothelial progenitor cell-derived conditioned medium mitigates chronic cerebral ischemic injury through macrophage migration inhibitory factor-activated AKT pathway Open
Background Chronic cerebral ischemia (CCI) is considered as a prelude to neurodegeneration. Endothelial progenitor cells (EPCs) have been implicated in revascularization and vascular repair in ischemic cerebrovascular diseases. However, du…
View article: Outcomes after fertility‐sparing surgery of early‐stage ovarian cancer: A nationwide population‐based study
Outcomes after fertility‐sparing surgery of early‐stage ovarian cancer: A nationwide population‐based study Open
Background Fertility‐sparing surgery (FSS) is an alternative choice of young patients who have not completed their family planning and still have fertility needs. The aims of this study were to compare the outcomes of early‐stage epithelia…
View article: EPCs-derived conditioned medium mitigates chronic cerebral ischemic injury through the MIF-activated AKT pathway
EPCs-derived conditioned medium mitigates chronic cerebral ischemic injury through the MIF-activated AKT pathway Open
Background Chronic cerebral ischemia (CCI) is considered as a prelude to neurodegeneration. Endothelial progenitor cells (EPCs) have been implicated in revascularization and vascular repair in cerebral ischemic diseases. Due to the safety …
View article: Parent-Youth Relationships and Youth Alcohol Use: The Moderating Role of Parental Alcohol Use
Parent-Youth Relationships and Youth Alcohol Use: The Moderating Role of Parental Alcohol Use Open
Previous studies have shown that strong parent-youth relationships serve as a protective factor inhibiting early alcohol use onset among youth, while parental alcohol use as a risk factor. However, little is known about the moderating effe…
View article: DNA mixture analyses of autosomal single nucleotide polymorphisms for individual identification using droplet digital polymerase-chain reaction and massively parallel sequencing in combination with EuroFormix
DNA mixture analyses of autosomal single nucleotide polymorphisms for individual identification using droplet digital polymerase-chain reaction and massively parallel sequencing in combination with EuroFormix Open
Droplet digital polymerase-chain reaction (ddPCR) and massively parallel sequencing (MPS) can be used to detect an extremely low proportion of non-overlapping single nucleotide polymorphisms (SNPs) of a minor contributor in a DNA mixture. …
View article: Genetic Investigation of the Origin of an Allograft Ureteral Carcinoma with Short Tandem Repeats: From Recipient or Donor?
Genetic Investigation of the Origin of an Allograft Ureteral Carcinoma with Short Tandem Repeats: From Recipient or Donor? Open
Purpose: The purpose of this study was to demonstrate the usefulness of genetic analysis with short tandem repeats (STRs) to identify the cellular origin of an unusual allograft urothelial carcinoma (UC). Materials and Methods: A 30-year-o…
View article: Outcomes After Fertility-sparing Surgery of Early-stage Ovarian Cancer: a Nationwide Population-based Study
Outcomes After Fertility-sparing Surgery of Early-stage Ovarian Cancer: a Nationwide Population-based Study Open
Here we investigated the outcomes of early-stage epithelial ovarian cancer (EOC) following fertility-sparing surgery (FSS)or radical comprehensive staging surgery (RCS), as well as the suitability of FSS.Our analysis included 1297 early-st…
View article: A proposed approach to confirm heroin administration – Regional differences in heroin purity is a major factor
A proposed approach to confirm heroin administration – Regional differences in heroin purity is a major factor Open
In forensic toxicology, a marker of street heroin use is urgent especially in the absence of urinary 6-monoacetylmorphine. ATM4G, the Glucuronide of Acetylated product of Thebaine compound 4 Metabolite (ATM4), arising from byproducts of st…
View article: Ecological Predictors and Trajectory of Internet Addiction from Childhood through Adolescence: A Nationally Representative Longitudinal Study
Ecological Predictors and Trajectory of Internet Addiction from Childhood through Adolescence: A Nationally Representative Longitudinal Study Open
We examined multidimensional factors within four systems (individual, family, school, and community) that influence internet addiction across time among children through adolescence in Taiwan. We hypothesize that internet addiction increas…
View article: DNA mixture interpretation using linear regression and neural networks on massively parallel sequencing data of single nucleotide polymorphisms
DNA mixture interpretation using linear regression and neural networks on massively parallel sequencing data of single nucleotide polymorphisms Open
Massively parallel sequencing (MPS) enables concurrent analysis of multiple single nucleotide polymorphisms (SNPs) and detection of alleles from minor contributors to extremely imbalanced DNA mixtures. To interpret the complex MPS data obt…
View article: Outcome and Subsequent Pregnancy after Fertility-Sparing Surgery of Early-Stage Cervical Cancers
Outcome and Subsequent Pregnancy after Fertility-Sparing Surgery of Early-Stage Cervical Cancers Open
We aimed to investigate the outcomes and subsequent pregnancies of early-stage cervical cancer patients who received conservative fertility-sparing surgery. Women with early-stage cervical cancer who underwent conservative or fertility-spa…
View article: HLA-G Expression in Human Mesenchymal Stem Cells (MSCs) Is Related to Unique Methylation Pattern in the Proximal Promoter as well as Gene Body DNA
HLA-G Expression in Human Mesenchymal Stem Cells (MSCs) Is Related to Unique Methylation Pattern in the Proximal Promoter as well as Gene Body DNA Open
Multipotent human mesenchymal stem cells (MSCs) harbor clinically relevant immunomodulation, and HLA-G, a non-classical MHC class I molecule with highly restricted tissue expression, is one important molecule involved in these processes. U…
View article: Characteristics of analytically confirmed illicit substance-using patients in the Emergency Department
Characteristics of analytically confirmed illicit substance-using patients in the Emergency Department Open
Our study provided the acute illicit substance complications at ED by LC-MS/MS analysis in Taiwan. Our study showed that more than one-third cases studied were NPS users. Young adults and polysubstance users were more common among NPS user…
View article: Determination of synthetic cathinone α‐pyrrolidinovalero‐phenone and its metabolite in urine using solid‐phase extraction and gas chromatography–mass spectrometry
Determination of synthetic cathinone α‐pyrrolidinovalero‐phenone and its metabolite in urine using solid‐phase extraction and gas chromatography–mass spectrometry Open
Rationale The presence of α‐pyrrolidinovalerophenone (α‐PVP) and its metabolites in urine is evidence of the administration of α‐PVP. A toxicological challenge is that the metabolites of α‐PVP exhibit amphoteric properties, which make them…
View article: Relationships between Parent-Reported Parenting, Child-Perceived Parenting, and Children’s Mental Health in Taiwanese Children
Relationships between Parent-Reported Parenting, Child-Perceived Parenting, and Children’s Mental Health in Taiwanese Children Open
The current study examines the relationship between parents’ and children’s reports of parenting and their effects on children’s mental health symptoms. Six hundred and sixty-six parent-child dyads in Taiwan participated in this study. The…
View article: Short tandem repeat analysis for confirmation of uterine non-gestational choriocarcinoma in a postmenopausal Taiwanese woman
Short tandem repeat analysis for confirmation of uterine non-gestational choriocarcinoma in a postmenopausal Taiwanese woman Open
STRs aid precise classification of rare choriocarcinoma. We encourage using the method to analyze suspicious choriocarcinoma.
View article: Cultural Perspective on Parenting, Trait Emotional Intelligence and Mental Health in Taiwanese Children
Cultural Perspective on Parenting, Trait Emotional Intelligence and Mental Health in Taiwanese Children Open
The current study aims to clarify the associations as well as the pathways through which
\nparenting and children's emotional intelligence (EI) may influence children's mental
\nhealth with a cross-sectional sample of 675 school pupils (fo…
View article: Associations between child maltreatment, PTSD, and internet addiction among Taiwanese students
Associations between child maltreatment, PTSD, and internet addiction among Taiwanese students Open
This study examines (1) the associations between multiple types of child maltreatment and Internet addiction, and (2) the mediating effects of post-traumatic stress disorder (PTSD) on these associations. We collected data from a national p…
View article: The Major Prognostic Features of Nuclear Receptor<i>NR5A2</i>in Infiltrating Ductal Breast Carcinomas
The Major Prognostic Features of Nuclear Receptor<i>NR5A2</i>in Infiltrating Ductal Breast Carcinomas Open
Background . Gene expression profiles of 181 breast cancer samples were analyzed to identify prognostic features of nuclear receptors NR5A1 and NR5A2 based upon their associated transcriptional networks. Methods . A supervised network anal…