Hoa Binh Nguyen
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View article: Preparation of diclofenac epolamine on a 100 g batch scale
Preparation of diclofenac epolamine on a 100 g batch scale Open
Diclofenac epolamine offers distinct advantages in solubility and permeability over other diclofenac salts, making it an excellent candidate for formulating transdermal patches or gels. Despite these benefits, existing published methods fo…
View article: From trials to programmatic scale-up: treatment outcomes of rifampicin-resistant tuberculosis during transition to short oral regimens in Vietnam (2021–2022)
From trials to programmatic scale-up: treatment outcomes of rifampicin-resistant tuberculosis during transition to short oral regimens in Vietnam (2021–2022) Open
During the transition from injectable-containing to all-oral short regimens, nationwide data showed 71.2% RR-TB treatment success in Vietnam. The wider use of STRs and addressing LTFU may further improve outcomes. More robust and better ma…
View article: Cardiopulmonary Resuscitation Induced Consciousness in Asystolic Cardiac Arrest: A Case Report from Vinmec Smart City Hospital, Vietnam
Cardiopulmonary Resuscitation Induced Consciousness in Asystolic Cardiac Arrest: A Case Report from Vinmec Smart City Hospital, Vietnam Open
Background: Cardiopulmonary resuscitation–induced consciousness (CPRIC) refers to the presence of awareness, motor activity, or purposeful movements during ongoing chest compressions in the absence of return of spontaneous circulation (ROS…
View article: Diagnostic Accuracy of the STANDARD F TB-Feron FIA Assay for Tuberculosis Infection in Vietnam: A Cross-Sectional Study
Diagnostic Accuracy of the STANDARD F TB-Feron FIA Assay for Tuberculosis Infection in Vietnam: A Cross-Sectional Study Open
Background Tuberculosis (TB) infection is a driver of the global TB epidemic. Accurate, affordable, and simpler diagnostics are crucial for identifying people for preventive therapy. We evaluated the diagnostic performance of the STANDARD …
View article: Potential impact, costs, and benefits of population-wide screening interventions for tuberculosis in Viet Nam: A mathematical modelling study
Potential impact, costs, and benefits of population-wide screening interventions for tuberculosis in Viet Nam: A mathematical modelling study Open
Population-wide screening may accelerate the decline of tuberculosis (TB) incidence, but the optimal screening algorithm and duration must weigh resource considerations. We calibrated a deterministic transmission model to TB epidemiology i…
View article: Impact of Case Detection and COVID-19-Related Disruptions on Tuberculosis in Vietnam: A Modeling Analysis
Impact of Case Detection and COVID-19-Related Disruptions on Tuberculosis in Vietnam: A Modeling Analysis Open
Background Vietnam, a high-burden tuberculosis (TB) country, experienced marked declines in TB notifications during the COVID-19 pandemic. We assessed the impact of pandemic-related disruptions on TB case detection and transmission using a…
View article: Evaluating the cost-effectiveness of levofloxacin therapy for household contacts of multidrug-resistant tuberculosis in Vietnam
Evaluating the cost-effectiveness of levofloxacin therapy for household contacts of multidrug-resistant tuberculosis in Vietnam Open
National Health and Medical Research Council Project Grant (#1081443). GJF was supported by a NHMRC Leadership Fellowship (Level 1) (#2007920).
View article: Optimizing use of data and evidence-related tools to complement routine surveillance systems for tuberculosis program planning
Optimizing use of data and evidence-related tools to complement routine surveillance systems for tuberculosis program planning Open
Background Challenges and gaps with routine tuberculosis (TB) data and surveillance systems are well-known. To address them, numerous TB data and evidence-related tools (e.g. surveys, assessments) have been developed to help countries coll…
View article: Long-term Outcomes Among People With Multidrug-Resistant Tuberculosis in Vietnam: A Prospective Cohort Study
Long-term Outcomes Among People With Multidrug-Resistant Tuberculosis in Vietnam: A Prospective Cohort Study Open
Background Existing rates of death and recurrent tuberculosis (TB) among people treated for rifampicin- or multidrug-resistant tuberculosis (RR/MDR-TB) are likely underestimates. We determined long-term disease outcomes among a cohort of p…
View article: A STUDY OF EXPERIMENTAL FUZZY CONTROL FOR BALL AND TUBE SYSTEM
A STUDY OF EXPERIMENTAL FUZZY CONTROL FOR BALL AND TUBE SYSTEM Open
This paper presents a fuzzy logic control approach for a real ball-in-tube system, which is a classical single-input, single-output (SISO) nonlinear system. The primary objective is to balance the ball's position at a fixed set point while…
View article: A life that’s worth living – measuring health-related quality of life among people treated for tuberculosis in Viet Nam: a longitudinal EQ-5D-5L survey
A life that’s worth living – measuring health-related quality of life among people treated for tuberculosis in Viet Nam: a longitudinal EQ-5D-5L survey Open
View article: Examining the challenges in sustaining user engagement with a mobile app to enhance multidrug-resistant tuberculosis (MDR-TB) care in Vietnam and its implications for implementing person-centred mHealth interventions
Examining the challenges in sustaining user engagement with a mobile app to enhance multidrug-resistant tuberculosis (MDR-TB) care in Vietnam and its implications for implementing person-centred mHealth interventions Open
Digital health technologies, especially mobile application (mHealth), offer great potential for enhancing person-centred care and managing MDR-TB. The rapid expansion of digital infrastructure in Vietnam presents a valuable opportunity for…
View article: Comparison of different Lunit INSIGHT CXR software versions when reading chest radiographs for tuberculosis
Comparison of different Lunit INSIGHT CXR software versions when reading chest radiographs for tuberculosis Open
New versions of computer-aided detection (CAD) software for chest X-ray (CXR) interpretation during tuberculosis (TB) screening are regularly released which purport to have incremental performance gains. No studies have independently asses…
View article: Prevalence of Xpert MTB/RIF Ultra Trace Call Results and Associated Risk Factors During Active Tuberculosis Case Finding in Viet Nam: A Programmatic Evaluation
Prevalence of Xpert MTB/RIF Ultra Trace Call Results and Associated Risk Factors During Active Tuberculosis Case Finding in Viet Nam: A Programmatic Evaluation Open
Background: The Xpert MTB/RIF Ultra assay (Ultra) is a second-generation molecular diagnostic test for tuberculosis (TB). The “Trace Call” result was added as a semi-quantitative category for extremely low bacillary loads. The prevalence a…
View article: Impact of Case Detection and COVID-19-Related Disruptions on Tuberculosis in Vietnam: A Modelling Analysis
Impact of Case Detection and COVID-19-Related Disruptions on Tuberculosis in Vietnam: A Modelling Analysis Open
Background Vietnam, a high-burden tuberculosis (TB) country, experienced marked declines in TB notifications during the COVID-19 pandemic. We assessed the impact of pandemic-related disruptions on TB case detection and transmission using a…
View article: An <scp>mHealth</scp> app technology to strengthen adverse event management of multi‐drug‐resistant tuberculosis in Vietnam: Protocol for a process evaluation of the V‐<scp>SMART</scp> trial
An <span>mHealth</span> app technology to strengthen adverse event management of multi‐drug‐resistant tuberculosis in Vietnam: Protocol for a process evaluation of the V‐<span>SMART</span> trial Open
Background Drug‐related adverse events cause poorer treatment outcomes amongst people with multi‐drug‐resistant tuberculosis, exacerbating a major global public health problem. The Harnessing new mHealth technologies to Strengthen the Mana…
View article: Distributional Surgery for Language Model Activations
Distributional Surgery for Language Model Activations Open
Language models, while capable of generating remarkably coherent and seemingly accurate text, can occasionally produce undesirable content, including harmful or toxic outputs. In this paper, we present a new two-stage approach to detect an…
View article: Bayesian spatio-temporal modelling of tuberculosis in Vietnam: Insights from a local-area analysis
Bayesian spatio-temporal modelling of tuberculosis in Vietnam: Insights from a local-area analysis Open
Spatial analysis and disease mapping have the potential to enhance understanding of tuberculosis (TB) dynamics, whose spatial dynamics may be complicated by the mix of short and long-range transmission and long latency periods. TB notifica…
View article: Active case finding to detect symptomatic and subclinical pulmonary tuberculosis disease: implementation of computer-aided detection for chest radiography in Viet Nam
Active case finding to detect symptomatic and subclinical pulmonary tuberculosis disease: implementation of computer-aided detection for chest radiography in Viet Nam Open
Objective: In Viet Nam, tuberculosis (TB) prevalence surveys revealed that approximately 98% of individuals with pulmonary TB have TB-presumptive abnormalities on chest radiographs, while 32% have no TB symptoms. This prompted the adoption…
View article: Potential impact, costs, and benefits of population-wide screening interventions for tuberculosis in Viet Nam: a mathematical modelling study
Potential impact, costs, and benefits of population-wide screening interventions for tuberculosis in Viet Nam: a mathematical modelling study Open
Background Population-wide screening may accelerate the decline of tuberculosis (TB) incidence, but the optimal screening algorithm and duration must weigh resource considerations. Methods We calibrated a deterministic transmission model t…
View article: A life that’s worth living – measuring health-related quality of life among people treated for tuberculosis in Viet Nam: a longitudinal EQ-5D-5L survey
A life that’s worth living – measuring health-related quality of life among people treated for tuberculosis in Viet Nam: a longitudinal EQ-5D-5L survey Open
Background In many settings, Tuberculosis (TB) represents a catastrophic life event that substantially impairs a person’s Health-Related Quality of Life (HRQoL). We aimed to measure the impact of TB disease and treatment on HRQoL in Viet N…
View article: Beyond the Binary: Investigating the Differential Effects of Microcredit on Poor and Near-Poor Households
Beyond the Binary: Investigating the Differential Effects of Microcredit on Poor and Near-Poor Households Open
This study employs difference-in-differences methodology to examine the impact of formal microcredit on income levels of poor and near-poor households in Vietnam using panel data from 2016-2018. Findings reveal microcredit participation le…
View article: Urine lipoarabinomannan concentrations among HIV-negative adults with pulmonary or extrapulmonary tuberculosis disease in Vietnam
Urine lipoarabinomannan concentrations among HIV-negative adults with pulmonary or extrapulmonary tuberculosis disease in Vietnam Open
Lipoarabinomannan (LAM) is a promising target biomarker for diagnosing subclinical and clinical tuberculosis (TB). Urine LAM (uLAM) testing using rapid diagnostic tests (RDTs) has been approved for people living with HIV (PLWH), however th…
View article: The implementation of whole-genome sequencing for <i>Mycobacterium tuberculosis</i> in Vietnam
The implementation of whole-genome sequencing for <i>Mycobacterium tuberculosis</i> in Vietnam Open
View article: An Effective Health System Approach to End TB: Implementing the Double X Strategy in Vietnam
An Effective Health System Approach to End TB: Implementing the Double X Strategy in Vietnam Open
Countries that are high burden for TB must reverse the COVID-19 pandemic's devastating effects to accelerate progress toward ending TB. Vietnam's Double X (2X) strategy uses chest radiography (CXR) and GeneXpert (Xpert) rapid diagnostic te…
View article: An mHealth technology to strengthen adverse event management of Multi-Drug Resistant Tuberculosis in Vietnam: Protocol for a process evaluation of the V-SMART trial
An mHealth technology to strengthen adverse event management of Multi-Drug Resistant Tuberculosis in Vietnam: Protocol for a process evaluation of the V-SMART trial Open
Background Drug-related adverse events cause poorer treatment outcomes among people with multi-drug-resistant tuberculosis (MDR/RR-TB), exacerbating a major global public health problem. The V-SMART trial tests whether a mobile health appl…
View article: Towards universal health coverage in Vietnam: a mixed-method case study of enrolling people with tuberculosis into social health insurance
Towards universal health coverage in Vietnam: a mixed-method case study of enrolling people with tuberculosis into social health insurance Open
Background Vietnam’s primary mechanism of achieving sustainable funding for universal health coverage (UHC) and financial protection has been through its social health insurance (SHI) scheme. Steady progress towards access has been made an…
View article: Is convenience really king? Comparative evaluation of catastrophic costs due to tuberculosis in the public and private healthcare sectors of Viet Nam: a longitudinal patient cost study
Is convenience really king? Comparative evaluation of catastrophic costs due to tuberculosis in the public and private healthcare sectors of Viet Nam: a longitudinal patient cost study Open
View article: Rifampicin resistant Mycobacterium tuberculosis in Vietnam, 2020–2022
Rifampicin resistant Mycobacterium tuberculosis in Vietnam, 2020–2022 Open
Drug resistance among most MDR-TB strains in Vietnam's two largest cities is confined largely to first-line drugs. Living with HIV is the main risk factor among patients with MDR-TB for having had a previous episode of tuberculosis.
View article: Tobacco smoking clusters in households affected by tuberculosis in an individual participant data meta-analysis of national tuberculosis prevalence surveys: Time for household-wide interventions?
Tobacco smoking clusters in households affected by tuberculosis in an individual participant data meta-analysis of national tuberculosis prevalence surveys: Time for household-wide interventions? Open
Tuberculosis (TB) and non-communicable diseases (NCD) share predisposing risk factors. TB-associated NCD might cluster within households affected with TB requiring shared prevention and care strategies. We conducted an individual participa…