Hoa Thi Le
YOU?
Author Swipe
View article: mGem: Immune recognition and clearance of bacteriophages—implications for phage therapy
mGem: Immune recognition and clearance of bacteriophages—implications for phage therapy Open
Bacteriophages (phages) hold significant promise as targeted antibacterial therapies in the era of rising multidrug-resistant infections. Despite their therapeutic potential, the clinical application of phages for human infections has been…
View article: Nasal-spraying Bacillus spore probiotics for pneumonia in children with respiratory syncytial virus and bacterial co-infections: a randomized clinical trial
Nasal-spraying Bacillus spore probiotics for pneumonia in children with respiratory syncytial virus and bacterial co-infections: a randomized clinical trial Open
Background Our study addresses the pressing need for safe and effective treatments for pneumonia in young children caused by respiratory syncytial virus (RSV) and bacterial co-infections. This issue is particularly urgent given the absence…
View article: Pharmacokinetics and Metabolism of Broad-Spectrum Antivirals Remdesivir and Obeldesivir with a Consideration to Metabolite GS-441524: Same, Similar, or Different?
Pharmacokinetics and Metabolism of Broad-Spectrum Antivirals Remdesivir and Obeldesivir with a Consideration to Metabolite GS-441524: Same, Similar, or Different? Open
RNA viruses with pandemic potential pose a significant global health risk. The adenosine nucleoside analog GS-441524 is metabolized to its active GS-443902 triphosphate metabolite to inhibit a broad spectrum of RNA viruses. Intravenous (IV…
View article: P-111. Promising Efficacy of Nasal-Spraying <i>Bacillus</i> Spore probiotics for Supportive Treatment of Pneumonia in Children with RSV and Bacterial Co-infections
P-111. Promising Efficacy of Nasal-Spraying <i>Bacillus</i> Spore probiotics for Supportive Treatment of Pneumonia in Children with RSV and Bacterial Co-infections Open
Background : Respiratory syncytial virus (RSV) and bacterial co-infections are primary cause of pneumonia. Recently, nasal-spraying Bacillus spore probiotics (LiveSpo NAVAX containing ≥ 5 billion/5mL B. subtilis and B. clausii spores) have…
View article: Experimental promoter identification of a foodborne pathogen Salmonella enterica subsp. enterica serovar Typhimurium with near single base-pair resolution
Experimental promoter identification of a foodborne pathogen Salmonella enterica subsp. enterica serovar Typhimurium with near single base-pair resolution Open
Salmonella enterica serovar Typhimurium ( S. Typhimurium) is a common foodborne pathogen which is frequently used as the reference strain for Salmonella . Investigating the sigma factor network and protomers is crucial to understand the ge…
View article: Enrichment and Maldi-Tof Ms/Ms Analysis of Phosphatidylinositol Bisphosphates in Brain Tissue
Enrichment and Maldi-Tof Ms/Ms Analysis of Phosphatidylinositol Bisphosphates in Brain Tissue Open
View article: P2.31-10 Clinical Outcomes of Real-World Treatment for Metastatic EGFRm NSCLC after Osimertinib and Platinum-Based Chemotherapy
P2.31-10 Clinical Outcomes of Real-World Treatment for Metastatic EGFRm NSCLC after Osimertinib and Platinum-Based Chemotherapy Open
View article: Characteristic of multiple-antibiotic-resistant \(\textit{ Salmonella enteritica }\) from Muscovy duck in Hanoi
Characteristic of multiple-antibiotic-resistant \(\textit{ Salmonella enteritica }\) from Muscovy duck in Hanoi Open
Nowadays, as the global population grows, the demand for food is also becoming higher each day. Together with the rise in food demand, Muscovy duck has been gradually bred industrially as a poultry food supply along with the chicken. The c…
View article: ChEAP: ChIP-exo analysis pipeline and the investigation of Escherichia coli RpoN protein-DNA interactions
ChEAP: ChIP-exo analysis pipeline and the investigation of Escherichia coli RpoN protein-DNA interactions Open
View article: Sustainable biosynthesis of chemicals from methane and glycerol via reconstruction of multi‐carbon utilizing pathway in obligate methanotrophic bacteria
Sustainable biosynthesis of chemicals from methane and glycerol via reconstruction of multi‐carbon utilizing pathway in obligate methanotrophic bacteria Open
Summary Obligate methanotrophic bacteria can utilize methane, an inexpensive carbon feedstock, as a sole energy and carbon substrate, thus are considered as the only nature‐provided biocatalyst for sustainable biomanufacturing of fuels and…
View article: Developments of Riboswitches and Toehold Switches for Molecular Detection—Biosensing and Molecular Diagnostics
Developments of Riboswitches and Toehold Switches for Molecular Detection—Biosensing and Molecular Diagnostics Open
Riboswitches and toehold switches are considered to have potential for implementation in various fields, i.e., biosensing, metabolic engineering, and molecular diagnostics. The specific binding, programmability, and manipulability of these…
View article: RL extraction of syntax-based chunks for sentence compression
RL extraction of syntax-based chunks for sentence compression Open
International audience
View article: Investigation of the absolute bioavailability and human mass balance of navoximod, a novel IDO1 inhibitor
Investigation of the absolute bioavailability and human mass balance of navoximod, a novel IDO1 inhibitor Open
Aims Navoximod (GDC‐0919, NLG‐919) is a small molecule inhibitor of indoleamine‐2,3‐dioxygenase 1 (IDO1), developed to treat the acquired immune tolerance associated with cancer. The primary objectives of this study were to assess navoximo…
View article: Combination of Microwave-Assisted Girard Derivatization with Ionic Liquid Matrix for Sensitive MALDI-TOF MS Analysis of Human Serum N-Glycans
Combination of Microwave-Assisted Girard Derivatization with Ionic Liquid Matrix for Sensitive MALDI-TOF MS Analysis of Human Serum N-Glycans Open
We developed a new method for MALDI-TOF MS detection of N-glycans derived from human serum. The synergistic combination of microwave-assisted Girard T derivatization, solid-phase extraction desalting, and an ionic liquid matrix (2, 5-dihyd…
View article: Multi-task dialog act and sentiment recognition on Mastodon
Multi-task dialog act and sentiment recognition on Mastodon Open
International audience
View article: Scaffold-Hopping Approach To Discover Potent, Selective, and Efficacious Inhibitors of NF-κB Inducing Kinase
Scaffold-Hopping Approach To Discover Potent, Selective, and Efficacious Inhibitors of NF-κB Inducing Kinase Open
NF-κB-inducing kinase (NIK) is a protein kinase central to the noncanonical NF-κB pathway downstream from multiple TNF receptor family members, including BAFF, which has been associated with B cell survival and maturation, dendritic cell a…
View article: Genetic diversity of the extremely rare Habenaria dentata and the rare Habenaria linearifolia (Orchidaceae) in South Korea: implications for population history and conservation
Genetic diversity of the extremely rare Habenaria dentata and the rare Habenaria linearifolia (Orchidaceae) in South Korea: implications for population history and conservation Open
Background and aims – Since historical events often leave an indelible mark on levels of genetic diversity of plant populations, one may indirectly infer their evolutionary history with the help of current patterns of genetic diversity. Th…
View article: Comparison of genetic variation between northern and southern populations of Lilium cernuum (Liliaceae): Implications for Pleistocene refugia
Comparison of genetic variation between northern and southern populations of Lilium cernuum (Liliaceae): Implications for Pleistocene refugia Open
The so-called "Baekdudaegan" (BDDG), a mountain range that stretches along the Korean Peninsula, has been recently proposed as a major "southern" glacial refugium for boreal or temperate plant species based on palaeoecological and, especia…
View article: Enhanced antidiabetic efficacy and safety of compound K⁄β-cyclodextrin inclusion complex in zebrafish
Enhanced antidiabetic efficacy and safety of compound K⁄β-cyclodextrin inclusion complex in zebrafish Open