Hock Chuan Yeo
YOU?
Author Swipe
View article: Identifying effective evolutionary strategies-based protocol for uncovering reaction kinetic parameters under the effect of measurement noises
Identifying effective evolutionary strategies-based protocol for uncovering reaction kinetic parameters under the effect of measurement noises Open
View article: Identifying effective evolutionary strategies for uncovering reaction kinetic parameters under the effect of measurement noises
Identifying effective evolutionary strategies for uncovering reaction kinetic parameters under the effect of measurement noises Open
The transition from explanative modelling of fitted data to the predictive modelling of unseen data for systems biology endeavors necessitates the effective recovery of reaction parameters. Yet, the relative efficacy of optimization algori…
View article: <scp>HISTONE DEACETYLASE</scp> 9 promotes hypocotyl‐specific auxin response under shade
<span>HISTONE DEACETYLASE</span> 9 promotes hypocotyl‐specific auxin response under shade Open
SUMMARY Vegetative shade causes an array of morphological changes in plants called shade avoidance syndrome, which includes hypocotyl and petiole elongation, leaf hyponasty, reduced leaf growth, early flowering and rapid senescence. Here, …
View article: Metabolomics and modelling approaches for systems metabolic engineering
Metabolomics and modelling approaches for systems metabolic engineering Open
View article: Machine learning alternative to systems biology should not solely depend on data
Machine learning alternative to systems biology should not solely depend on data Open
In recent years, artificial intelligence (AI)/machine learning has emerged as a plausible alternative to systems biology for the elucidation of biological phenomena and in attaining specified design objective in synthetic biology. Although…
View article: Comparative Transcriptome Analysis Reveals Coordinated Transcriptional Regulation of Central and Secondary Metabolism in the Trichomes of Cannabis Cultivars
Comparative Transcriptome Analysis Reveals Coordinated Transcriptional Regulation of Central and Secondary Metabolism in the Trichomes of Cannabis Cultivars Open
Cannabis is one of the few plant genera capable of producing cannabinoids, the effects of which are synergized by terpene interactions. As the biosynthesis of both metabolite classes requires the same intracellular feedstocks, this work de…
View article: Comparative phenotypic and transcriptomic analyses unravel conserved and distinct mechanisms underlying shade avoidance syndrome in Brassicaceae vegetables
Comparative phenotypic and transcriptomic analyses unravel conserved and distinct mechanisms underlying shade avoidance syndrome in Brassicaceae vegetables Open
Background Plants grown under shade are exposed to low red/far-red ratio, thereby triggering an array of altered phenotypes called shade avoidance syndrome (SAS). Shade negatively influences plant growth, leading to a reduction in agricult…
View article: Combined multivariate statistical and flux balance analyses uncover media bottlenecks to the growth and productivity of CHO cell cultures
Combined multivariate statistical and flux balance analyses uncover media bottlenecks to the growth and productivity of CHO cell cultures Open
Chinese hamster ovary (CHO) cells are widely used for producing recombinant proteins. To enhance their growth, productivity, and product quality, practically media reformulation has been one of key focuses with several technical challenges…
View article: Additional file 4 of Comparative phenotypic and transcriptomic analyses unravel conserved and distinct mechanisms underlying shade avoidance syndrome in Brassicaceae vegetables
Additional file 4 of Comparative phenotypic and transcriptomic analyses unravel conserved and distinct mechanisms underlying shade avoidance syndrome in Brassicaceae vegetables Open
Additional file 4. Supplementary Dataset 3 listing 95 and 430 common DEGs (associated with Fig. 4).
View article: Additional file 3 of Comparative phenotypic and transcriptomic analyses unravel conserved and distinct mechanisms underlying shade avoidance syndrome in Brassicaceae vegetables
Additional file 3 of Comparative phenotypic and transcriptomic analyses unravel conserved and distinct mechanisms underlying shade avoidance syndrome in Brassicaceae vegetables Open
Additional file 3. Supplementary Dataset 2 listing 139 and 297 common DEGs (associated with Fig. 3).
View article: Additional file 2 of Comparative phenotypic and transcriptomic analyses unravel conserved and distinct mechanisms underlying shade avoidance syndrome in Brassicaceae vegetables
Additional file 2 of Comparative phenotypic and transcriptomic analyses unravel conserved and distinct mechanisms underlying shade avoidance syndrome in Brassicaceae vegetables Open
Additional file 2. Supplementary Dataset 1 indicating GO analysis of 8 DEGs clusters (associated with Fig. S5).
View article: Enzyme capacity-based genome scale modelling of CHO cells
Enzyme capacity-based genome scale modelling of CHO cells Open
Chinese hamster ovary (CHO) cells are most prevalently used for producing recombinant therapeutics in biomanufacturing. Recently, more rational and systems approaches have been increasingly exploited to identify key metabolic bottlenecks a…
View article: Mammalian Systems Biotechnology Reveals Global Cellular Adaptations in a Recombinant CHO Cell Line
Mammalian Systems Biotechnology Reveals Global Cellular Adaptations in a Recombinant CHO Cell Line Open
View article: Genome-Wide Transcriptome and Binding Sites Analyses Identify Early FOX Expressions for Enhancing Cardiomyogenesis Efficiency of hESC Cultures
Genome-Wide Transcriptome and Binding Sites Analyses Identify Early FOX Expressions for Enhancing Cardiomyogenesis Efficiency of hESC Cultures Open