Hossam El‐Sheikh Ali
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View article: Expression pattern of the HIFα-family in equine chorioallantois during pregnancy and placental pathology
Expression pattern of the HIFα-family in equine chorioallantois during pregnancy and placental pathology Open
Equine placental dysfunction impairs fetal growth and disrupts pregnancy outcomes. Despite many advances in diagnosis, the molecular pathophysiology of equine placentitis and premature placental separation remains poorly understood. Howeve…
View article: Staging discordance in apparent early-stage ovarian neoplasms: prevalence, prognosis, and practical risk stratification
Staging discordance in apparent early-stage ovarian neoplasms: prevalence, prognosis, and practical risk stratification Open
Up to 1 in 13 patients with apparent early-stage ovarian neoplasms harbor occult advanced disease, posing a diagnostic dilemma with major therapeutic implications that remains poorly characterized. We conducted a retrospective consecutive …
View article: Life Saving Cure, Harmful Turn: PTU-Induced Neutropenia in a Patient with Thyroid Storm
Life Saving Cure, Harmful Turn: PTU-Induced Neutropenia in a Patient with Thyroid Storm Open
Though it stands as the first line and life-saving therapeutic option in thyroid storms, Propylthiouracil (PTU) remains a double-edged sword, fraught with rare yet potentially life-threatening adverse effects. This case report underscores …
View article: Decoding the amniotic membrane transcriptome during equine ascending placentitis
Decoding the amniotic membrane transcriptome during equine ascending placentitis Open
Despite its critical role in protecting the fetus, the amniotic membrane remains poorly understood in the context of disease response. The equine amniotic membrane is an important physical barrier to the amniotic compartment, and there is …
View article: Gestation-Stage Related Changes in the IGF System Components in the Equine Placenta
Gestation-Stage Related Changes in the IGF System Components in the Equine Placenta Open
The insulin-like growth factor (IGF) system regulates implantation, placental development, and angiogenesis in eutherian mammals. However, little is known about the changes in this system in equine placenta (chorioallantois; CA) and the en…
View article: Antioxidant Effect of Hibiscus sabdariffa Calyces Aqueous Extract Against Sleep Deprivation-induced Pituitary, Testicular and Epidydimal Oxidative Damage in Wistar Rats
Antioxidant Effect of Hibiscus sabdariffa Calyces Aqueous Extract Against Sleep Deprivation-induced Pituitary, Testicular and Epidydimal Oxidative Damage in Wistar Rats Open
Sleep deprivation can significantly impact male fertility. Ensuring sufficient and quality sleep is crucial for maintaining optimal reproductive health. This study evaluated the effect of Hibiscus sabdariffa calyces against sleep deprivati…
View article: The Ameliorative Potentials of L-Citrulline on Short Term Memory Deficit and Oxidative Changes in Paraquat-induced Parkinsonism in Adult Male Wistar Rats
The Ameliorative Potentials of L-Citrulline on Short Term Memory Deficit and Oxidative Changes in Paraquat-induced Parkinsonism in Adult Male Wistar Rats Open
Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by the loss of dopamine-producing neurons in the substantia nigra, affecting movement and cognition. While genetics and aging play roles in its onset, envir…
View article: Investigating computed tomography radiographers’ expertise in responding to severe contrast media reactions: a cross-sectional study
Investigating computed tomography radiographers’ expertise in responding to severe contrast media reactions: a cross-sectional study Open
View article: Safety of Misoprostol in Labor Induction for Twin Pregnancies: A Systematic Review
Safety of Misoprostol in Labor Induction for Twin Pregnancies: A Systematic Review Open
View article: Determinants of obstetric vesicovaginal fistula surgery at the National Reference Center for Obstetric Fistula (CNRFO)
Determinants of obstetric vesicovaginal fistula surgery at the National Reference Center for Obstetric Fistula (CNRFO) Open
Vesicovaginal fistula is a major public health problem in sub-Saharan Africa in general and in Niger in particular. The objective was to study the determinants of obstetric surgery of the vesicovaginal fistula. This was a cross-sectional, …
View article: Antimicrobial Resistance in Equines: A Growing Threat to Horse Health and Beyond—A Comprehensive Review
Antimicrobial Resistance in Equines: A Growing Threat to Horse Health and Beyond—A Comprehensive Review Open
The equine industry holds substantial economic importance not only in the USA but worldwide. The occurrence of various infectious bacterial diseases in horses can lead to severe health issues, economic losses, and restrictions on horse mov…
View article: Characterization of the equine placental microbial population during nocardioform placentitis
Characterization of the equine placental microbial population during nocardioform placentitis Open
View article: Isolated pseudo‑abducens palsy and contralateral occipital headache with thalamic stroke: A case report and mini‑review of the literature
Isolated pseudo‑abducens palsy and contralateral occipital headache with thalamic stroke: A case report and mini‑review of the literature Open
The abducens nerve (sixth cranial nerve) is essential for lateral eye movement, and its malfunction can cause a variety of issues with vision. Pseudo-abducens palsy is a rare neurological condition that causes a limitation in eye abduction…
View article: Epidemiological Study of Prevalence of Entrapment Neuropathies Among Pregnant Women Attending the Hospital and Health Care Center in New Damietta
Epidemiological Study of Prevalence of Entrapment Neuropathies Among Pregnant Women Attending the Hospital and Health Care Center in New Damietta Open
Background: Reproductive hormone release during pregnancy induces a cascade of other physiological changes that can have an impact on the peripheral nerve. Meralgia paresthetica and carpal tunnel syndrome are two entrapment neuropathies th…
View article: Characterization of the equine placental microbial population in healthy pregnancies
Characterization of the equine placental microbial population in healthy pregnancies Open
View article: Dynamics of the Equine Placental DNA Methylome and Transcriptome from Mid- to Late Gestation
Dynamics of the Equine Placental DNA Methylome and Transcriptome from Mid- to Late Gestation Open
The placenta is a temporary organ that is essential for the survival of the fetus, with a lifelong effect on the health of both the offspring and the dam. The functions of the placenta are controlled by its dynamic gene expression during g…
View article: Galectins in Equine Placental Disease
Galectins in Equine Placental Disease Open
Galectins are proteins that bind to glycans in targeted cells and function in cell-to-cell signaling throughout the body. Galectins have been found to be involved in various reproductive processes, including placental dysfunction, but this…
View article: The effect of season and ovarian storage time on oocytes recovery and quality in dromedary camel
The effect of season and ovarian storage time on oocytes recovery and quality in dromedary camel Open
View article: Galectinology of Equine Pregnancy
Galectinology of Equine Pregnancy Open
Galectins are a family of proteins that bind to glycans, acting in a cytokine-like manner throughout the body. In the majority of mammalians, galectins have been found to be involved in pregnancy maintenance, but few studies have evaluated…
View article: Importance of Antioxidant Supplementation during In Vitro Maturation of Mammalian Oocytes
Importance of Antioxidant Supplementation during In Vitro Maturation of Mammalian Oocytes Open
The in vitro embryo production (IVEP) technique is widely used in the field of reproductive biology. In vitro maturation (IVM) is the first and most critical step of IVEP, during which, the oocyte is matured in an artificial maturation med…
View article: Lycopene Reduces the In Vitro Aging Phenotypes of Mouse Oocytes by Improving Their Oxidative Status
Lycopene Reduces the In Vitro Aging Phenotypes of Mouse Oocytes by Improving Their Oxidative Status Open
Postovulatory aging is a major problem that limits the success of many assisted reproductive technologies (ARTs). Oxidative stress is a leading cause of oocyte aging. This study investigated the effects of lycopene supplementation of in vi…
View article: Online medical education in Egypt during the COVID-19 pandemic: a nationwide assessment of medical students’ usage and perceptions
Online medical education in Egypt during the COVID-19 pandemic: a nationwide assessment of medical students’ usage and perceptions Open
Background The coronavirus (COVID-19) pandemic required a transformation of medical education in Egypt. Public health measures necessitated a rapid shift from traditional face to face lectures to largely online platforms following campus c…
View article: Lycopene Improves Maturation Rate and Antioxidant Status of in vitro Matured Mouse Oocytes
Lycopene Improves Maturation Rate and Antioxidant Status of in vitro Matured Mouse Oocytes Open
The present study aimed to investigate the effect of lycopene supplementation to the in vitro maturation (IVM) medium of mouse oocytes on their maturation rate and oxidative biomarkers levels. Lycopene concentrations of 50, 100, 200, and 4…
View article: Transcriptional and Histochemical Signatures of Bone Marrow Mononuclear Cell-Mediated Resolution of Synovitis
Transcriptional and Histochemical Signatures of Bone Marrow Mononuclear Cell-Mediated Resolution of Synovitis Open
Osteoarthritis (OA) may result from impaired ability of synovial macrophages to resolve joint inflammation. Increasing macrophage counts in inflamed joints through injection with bone marrow mononuclear cells (BMNC) induces lasting resolut…
View article: Transcriptomic analysis of equine chorioallantois reveals immune networks and molecular mechanisms involved in nocardioform placentitis
Transcriptomic analysis of equine chorioallantois reveals immune networks and molecular mechanisms involved in nocardioform placentitis Open
View article: A community-Based Epidemiological Study of Epilepsy among Students of Primary and Preparatory School Stages in New Damietta City
A community-Based Epidemiological Study of Epilepsy among Students of Primary and Preparatory School Stages in New Damietta City Open
Background:Even though Epilepsy is a common neurological disorder globally, developing countries still have insufficient epidemiological data regarding epilepsy. Aim of the Work:We aimed to estimate the prevalence of epilepsy in primary an…
View article: Serum amyloid A, Serum Amyloid A1 and Haptoglobin in pregnant mares and their fetuses after experimental induction of placentitis
Serum amyloid A, Serum Amyloid A1 and Haptoglobin in pregnant mares and their fetuses after experimental induction of placentitis Open
View article: Parental bias in expression and interaction of genes in the equine placenta
Parental bias in expression and interaction of genes in the equine placenta Open
Significance The placenta is the fetomaternal interface, which is essential for fetal growth and survival, playing a central role in the health of both the fetus and its mother. The dynamic gene expression during pregnancy dramatically con…
View article: Equine cervical remodeling during placentitis and the prepartum period: a transcriptomic approach
Equine cervical remodeling during placentitis and the prepartum period: a transcriptomic approach Open
Cervical remodeling is a critical component in both term and preterm labor in eutherian mammals. However, the molecular mechanisms underlying cervical remodeling remain poorly understood in the mare. The current study compared the transcri…
View article: Paternally expressed retrotransposon Gag-like 1 gene, <i>RTL1</i>, is one of the crucial elements for placental angiogenesis in horses
Paternally expressed retrotransposon Gag-like 1 gene, <i>RTL1</i>, is one of the crucial elements for placental angiogenesis in horses Open
RTL1 (retrotransposon Gag-like 1) is an essential gene in the development of the human and murine placenta. Several fetal and placental abnormalities such as intrauterine growth restriction (IUGR) and hydrops conditions have been associate…