Homaira Hamidzada
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View article: Primitive macrophages enable long-term vascularization of human heart-on-a-chip platforms
Primitive macrophages enable long-term vascularization of human heart-on-a-chip platforms Open
View article: Primitive macrophages induce sarcomeric maturation and functional enhancement of developing human cardiac microtissues via efferocytic pathways
Primitive macrophages induce sarcomeric maturation and functional enhancement of developing human cardiac microtissues via efferocytic pathways Open
View article: Knockout of endoplasmic reticulum‐localized molecular chaperone <scp>HSP90</scp>.7 impairs seedling development and cellular auxin homeostasis in Arabidopsis
Knockout of endoplasmic reticulum‐localized molecular chaperone <span>HSP90</span>.7 impairs seedling development and cellular auxin homeostasis in Arabidopsis Open
SUMMARY The Arabidopsis endoplasmic reticulum‐localized heat shock protein HSP90.7 modulates tissue differentiation and stress responses; however, complete knockout lines have not been previously reported. In this study, we identified and …
View article: Modeling cardiac fibroblast heterogeneity from human pluripotent stem cell-derived epicardial cells
Modeling cardiac fibroblast heterogeneity from human pluripotent stem cell-derived epicardial cells Open
View article: Modeling cardiac fibroblast heterogeneity from human pluripotent stem cell-derived epicardial cells
Modeling cardiac fibroblast heterogeneity from human pluripotent stem cell-derived epicardial cells Open
(Summary) Cardiac fibroblasts play an essential role in the development of the heart and have been implicated in disease progression in the context of fibrosis and regeneration. Here, we established a simple organoid culture platform using…
View article: Microbial energy metabolism fuels an intestinal macrophage niche in solitary isolated lymphoid tissues through purinergic signaling
Microbial energy metabolism fuels an intestinal macrophage niche in solitary isolated lymphoid tissues through purinergic signaling Open
Maintaining macrophage (MΦ) heterogeneity is critical to ensure intestinal tissue homeostasis and host defense. The gut microbiota and host factors are thought to synergistically guide intestinal MΦ development, although the exact nature, …
View article: Facilitated Study Groups for Undergraduate Organic Chemistry: Experience from a Large Public Canadian University
Facilitated Study Groups for Undergraduate Organic Chemistry: Experience from a Large Public Canadian University Open
Undergraduate organic chemistry courses have a reputation for being difficult among students in biological and physical sciences programs. Due to the extensive problem-solving, visualization, and depiction of chemical structures/reactions …
View article: Knockout of endoplasmic reticulum localized molecular chaperone HSP90.7 impairs seeding development and cellular auxin homeostasis in Arabidopsis
Knockout of endoplasmic reticulum localized molecular chaperone HSP90.7 impairs seeding development and cellular auxin homeostasis in Arabidopsis Open
SUMMARY The Arabidopsis endoplasmic reticulum localized heat shock protein HSP90.7 modulates tissue differentiation and stress responses; however, complete knockout lines have not been previously reported. In this study, we identified and …
View article: Microbial Energy Metabolism Fuels a CSF2-dependent Intestinal Macrophage Niche within Tertiary Lymphoid Organs
Microbial Energy Metabolism Fuels a CSF2-dependent Intestinal Macrophage Niche within Tertiary Lymphoid Organs Open
Summary Maintaining intestinal macrophage (MP) heterogeneity is critical to ensure tissue homeostasis and host defense. The gut microbiota and host factors are thought to synergistically shape colonic MP development, although there remains…
View article: Single cell biology—a Keystone Symposia report
Single cell biology—a Keystone Symposia report Open
Single cell biology has the potential to elucidate many critical biological processes and diseases, from development and regeneration to cancer. Single cell analyses are uncovering the molecular diversity of cells, revealing a clearer pict…
View article: Pleiotropic Roles of Cytokines in HIV-1 Pathogenesis and Control: A Literature Review
Pleiotropic Roles of Cytokines in HIV-1 Pathogenesis and Control: A Literature Review Open
Introduction: Human Immunodeficiency Virus (HIV) is a retrovirus that infects human immune cells, primarily CD4+ T cells and macrophages. During HIV disease progression, infected individuals have declining CD4+ T cell counts and increasing…