Luqiao Wang
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View article: Comparative chloroplast genomics of Rutaceae: structural divergence, adaptive evolution, and phylogenomic implications
Comparative chloroplast genomics of Rutaceae: structural divergence, adaptive evolution, and phylogenomic implications Open
The study of chloroplast genome evolutionary dynamics provides critical insights into plant adaptive evolution and phylogenetic relationships. This research conducted a systematic comparative analysis of chloroplast genomes across 35 speci…
View article: Associations between genetic predispositions for specific gut microbiota, serum ferritin, and blood lipids: A Mendelian randomization study
Associations between genetic predispositions for specific gut microbiota, serum ferritin, and blood lipids: A Mendelian randomization study Open
Our study explores the bidirectional causal relationship between gut microbiota and serum ferritin and investigates the mediation of serum ferritin in the causal relationship between specific gut microbiota and circulating lipids. We utili…
View article: Olive Intake and Coronary Heart Disease: A Mendelian Randomization Study
Olive Intake and Coronary Heart Disease: A Mendelian Randomization Study Open
Objective: This study aimed to explore the causal link between olive intake and the occurrence of coronary heart disease (CHD) using Mendelian randomization (MR). Methods: In this study, genome-wide association study data from IEU OpenGWAS…
View article: CircRNA Networks in CAD: Multi-Cellular Mechanisms and Clinical Potential
CircRNA Networks in CAD: Multi-Cellular Mechanisms and Clinical Potential Open
Coronary artery disease (CAD), is a global cardiovascular disease that is characterized by myocardial ischemia and hypoxia caused by coronary artery occlusion. Circular RNAs (CircRNAs) is a particular kind of endogenous non-coding RNA, whi…
View article: Machine learning for predicting all-cause mortality of metabolic dysfunction-associated fatty liver disease: a longitudinal study based on NHANES
Machine learning for predicting all-cause mortality of metabolic dysfunction-associated fatty liver disease: a longitudinal study based on NHANES Open
View article: Erratum for the Clinical and Translational Medicine “Multi‐omics integration reveals the oncogenic role of eccDNAs in diffuse large B‐cell lymphoma through STING signalling” by Zijuan Wu et al.
Erratum for the Clinical and Translational Medicine “Multi‐omics integration reveals the oncogenic role of eccDNAs in diffuse large B‐cell lymphoma through STING signalling” by Zijuan Wu et al. Open
View article: Retraction Notice to: Overexpression of circRNA circUCK2 Attenuates Cell Apoptosis in Cerebral Ischemia-Reperfusion Injury via miR-125b-5p/GDF11 Signaling
Retraction Notice to: Overexpression of circRNA circUCK2 Attenuates Cell Apoptosis in Cerebral Ischemia-Reperfusion Injury via miR-125b-5p/GDF11 Signaling Open
View article: Bioinformatics analysis of immune infiltration in human diabetic retinopathy and identification of immune-related hub genes and their ceRNA networks
Bioinformatics analysis of immune infiltration in human diabetic retinopathy and identification of immune-related hub genes and their ceRNA networks Open
View article: Multi‐omics integration reveals the oncogenic role of eccDNAs in diffuse large B‐cell lymphoma through STING signalling
Multi‐omics integration reveals the oncogenic role of eccDNAs in diffuse large B‐cell lymphoma through STING signalling Open
Background Extrachromosomal circular DNAs (eccDNAs), a type of double‐stranded DNAs (dsDNAs) that facilitate the activation of the DNA sensing machinery, have been implicated in the progression and prognosis of various diseases. While the …
View article: Identification and validation of prognostic signature and immune infiltrate characteristics for acute myocardial infarction based on neutrophil extracellular traps
Identification and validation of prognostic signature and immune infiltrate characteristics for acute myocardial infarction based on neutrophil extracellular traps Open
Background Coronary artery blockage can lead to acute myocardial infarction (AMI), characterized by myocardial ischemia, necrosis, and compromised cardiac function. Recent studies highlight the significance of neutrophil extracellular trap…
View article: CD22-targeted glyco-engineered natural killer cells offer a further treatment option for B-cell acute lymphoblastic leukemia
CD22-targeted glyco-engineered natural killer cells offer a further treatment option for B-cell acute lymphoblastic leukemia Open
Not available.
View article: Ferroptosis and Lipid Metabolism in Acute Myocardial Infarction
Ferroptosis and Lipid Metabolism in Acute Myocardial Infarction Open
Acute myocardial infarction (AMI) is triggered by the blockage of coronary arteries, leading to restricted blood flow to the myocardium, which results in damage and cell death. While the traditional understanding of cell death primarily re…
View article: Study on the relationship between oxidative stress gene and sepsis-induced cardiomyopathy (SIC) based on ceRNA network
Study on the relationship between oxidative stress gene and sepsis-induced cardiomyopathy (SIC) based on ceRNA network Open
Sepsis-induced cardiomyopathy (SIC) is a kind of cardiac dysfunction caused by severe sepsis, which increases the risk of heart failure and death. The molecular mechanism of its pathogenesis is still unclear. It is reported that oxidative …
View article: Integrated analysis and validation of ferroptosis-related genes and immune infiltration in acute myocardial infarction
Integrated analysis and validation of ferroptosis-related genes and immune infiltration in acute myocardial infarction Open
Background Acute myocardial infarction (AMI) is indeed a significant cause of mortality and morbidity in individuals with coronary heart disease. Ferroptosis, an iron-dependent cell death, is characterized by the accumulation of intracellu…
View article: RBM25 binds to and regulates alternative splicing levels of <i>Slc38a9, Csf1,</i> and <i>Coro6</i> to affect immune and inflammatory processes in H9c2 cells
RBM25 binds to and regulates alternative splicing levels of <i>Slc38a9, Csf1,</i> and <i>Coro6</i> to affect immune and inflammatory processes in H9c2 cells Open
Background Alternative splicing (AS) is a biological process that allows genes to be translated into diverse proteins. However, aberrant AS can predispose cells to aberrations in biological mechanisms. RNA binding proteins (RBPs), closely …
View article: Inherent-attribute-aware dual-graph autoencoder for rating prediction
Inherent-attribute-aware dual-graph autoencoder for rating prediction Open
Autoencoder-based rating prediction methods with external attributes have received wide attention due to their ability to accurately capture users' preferences. However, existing methods still have two significant limitations: i) External …
View article: Promising roles of non-exosomal and exosomal non-coding RNAs in the regulatory mechanism and as diagnostic biomarkers in myocardial infarction
Promising roles of non-exosomal and exosomal non-coding RNAs in the regulatory mechanism and as diagnostic biomarkers in myocardial infarction Open
Non-exosomal non-coding RNAs (non-exo-ncRNAs) and exosomal ncRNAs (exo-ncRNAs) have been associated with the pathological development of myocardial infarction (MI). Accordingly, this analytical review provides an overview of current MI stu…
View article: Role of LncRNAs in the Pathogenesis of Coronary Artery Disease
Role of LncRNAs in the Pathogenesis of Coronary Artery Disease Open
Coronary artery disease (CAD), caused by coronary artery occlusion, is a common cardiovascular disease worldwide. Long non-coding RNAs (lncRNAs) are implicated in the regulation of endothelial cell injury, angiogenesis, plaque formation, a…
View article: Dual-Tower Model with Semantic Perception and Timespan-Coupled Hypergraph for Next Basket Recommendation
Dual-Tower Model with Semantic Perception and Timespan-Coupled Hypergraph for Next Basket Recommendation Open
View article: Longitudinal Associations of Work Stress with Changes in Quality of Life among Patients after Acute Coronary Syndrome: A Hospital-Based Study
Longitudinal Associations of Work Stress with Changes in Quality of Life among Patients after Acute Coronary Syndrome: A Hospital-Based Study Open
(1) Background: Targeting a sample of Chinese employees in this study, the correlation of work stress with changes in quality of life (QoL) was explored subsequent to acute coronary syndrome (ACS). (2) Methods: Patients suffering from the …
View article: Identification of immune-related hub genes and miRNA-mRNA pairs involved in immune infiltration in human septic cardiomyopathy by bioinformatics analysis
Identification of immune-related hub genes and miRNA-mRNA pairs involved in immune infiltration in human septic cardiomyopathy by bioinformatics analysis Open
Septic cardiomyopathy (SCM) is a serious complication caused by sepsis that will further exacerbate the patient's prognosis. However, immune-related genes (IRGs) and their molecular mechanism during septic cardiomyopathy are largely unknow…
View article: Integrated bioinformatics analysis for novel miRNAs markers and ceRNA network in diabetic retinopathy
Integrated bioinformatics analysis for novel miRNAs markers and ceRNA network in diabetic retinopathy Open
In order to seek a more outstanding diagnosis and treatment of diabetic retinopathy (DR), we predicted the miRNA biomarkers of DR and explored the pathological mechanism of DR through bioinformatics analysis. Method: Based on public omics …
View article: CircRIC8B regulates the lipid metabolism of chronic lymphocytic leukemia through miR199b-5p/LPL axis
CircRIC8B regulates the lipid metabolism of chronic lymphocytic leukemia through miR199b-5p/LPL axis Open
Objective Circular RNAs (circRNAs) play a critical role in the modulation of tumor metabolism. However, the expression patterns and metabolic function of circRNAs in chronic lymphocytic leukemia (CLL) remain largely unknown. This study aim…
View article: Exploring the significance of <scp>PAK1</scp> through chromosome conformation signatures in ibrutinib‐resistant chronic lymphocytic leukaemia
Exploring the significance of <span>PAK1</span> through chromosome conformation signatures in ibrutinib‐resistant chronic lymphocytic leukaemia Open
Ibrutinib exerts promising anticancer effects in chronic lymphocytic leukaemia (CLL). However, acquired resistance occurs during treatment, necessitating the exploration of underlying mechanisms. Although three‐dimensional genome organizat…
View article: Identification and Validation of Immune-Related Biomarker Gene and Construction of ceRNA Networks in Septic Cardiomyopathy
Identification and Validation of Immune-Related Biomarker Gene and Construction of ceRNA Networks in Septic Cardiomyopathy Open
Septic cardiomyopathy (SCM) is a cardiac dysfunction caused by severe sepsis, which greatly increases the risk of heart failure and death, and its molecular mechanism is unclear. The immune response has been reported to be an important pro…
View article: Single‐cell profiling‐guided combination therapy of c‐Fos and histone deacetylase inhibitors in diffuse large B‐cell lymphoma
Single‐cell profiling‐guided combination therapy of c‐Fos and histone deacetylase inhibitors in diffuse large B‐cell lymphoma Open
Background Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of non‐Hodgkin lymphoma. Histone deacetylase inhibitors (HDACis) have been widely applied in multiple tumours, but the expected efficacy was not observed in DLBCL.…
View article: Identification of Key ncRNAs and ceRNA Network in DR via Bioinformation Analysis
Identification of Key ncRNAs and ceRNA Network in DR via Bioinformation Analysis Open
This study aimed to find potential diagnostic biomarkers for diabetic retinopathy (DR) , explore its ceRNA mechanism and analyze the role of immune cell infiltration in DR. Method. Three microarray datasets for human retina tissues and aqu…
View article: Additional file 9 of CircRIC8B regulates the lipid metabolism of chronic lymphocytic leukemia through miR199b-5p/LPL axis
Additional file 9 of CircRIC8B regulates the lipid metabolism of chronic lymphocytic leukemia through miR199b-5p/LPL axis Open
Additional file 1: Table S1. Primer sequences used in qRT-PCR and PCR analysis
View article: Additional file 7 of CircRIC8B regulates the lipid metabolism of chronic lymphocytic leukemia through miR199b-5p/LPL axis
Additional file 7 of CircRIC8B regulates the lipid metabolism of chronic lymphocytic leukemia through miR199b-5p/LPL axis Open
Additional file 3: Table S3. Genes that positively correlated with circRIC8B (R>0.5).
View article: Additional file 6 of CircRIC8B regulates the lipid metabolism of chronic lymphocytic leukemia through miR199b-5p/LPL axis
Additional file 6 of CircRIC8B regulates the lipid metabolism of chronic lymphocytic leukemia through miR199b-5p/LPL axis Open
Additional file 2: Table S2. Metabolic score of 53 CLL patients