Explanipedia

Development and optimization of a Defined Serum-Free Medium for Muscle satellite cells towards sustainable meat cultivation Open

Jiawei Du, Q. Qin, Linzi Li, Hafiz Qadeer Ahmed, Sihu Wang , et al. · 2025

Cultured meat offers a promising alternative to conventional meat but relies heavily on fetal bovine serum (FBS), limiting scalability. Therefore, the creation of scalable, animal-free, and biologically compatible culture systems is essent…

‘Jimei’—A Late-maturing Pear Cultivar Open

Hongbao Wang, Yongbo Wang, Yaru Wang, Jin Wang, Yuekun Yang , et al. · 2025

Knowledge, attitude, and practice toward coronary heart disease secondary prevention among coronary heart disease patients in Shanghai, China Open

Hao Wang, Bo Wu, Wenqi Guan, Zhou Tan, Hongbao Wang , et al. · 2025

Background This study aimed to investigate knowledge, attitude, and practice (KAP) toward coronary heart disease (CHD) secondary prevention among CHD patients. Methods This web-based cross-sectional study enrolled patients with CHD who vis…

Study on the Regional Applicability of Solar-Powered Zero-Carbon Refrigerated Display Cabinet Across China Open

Bo Zhang, Ming Bao, Lina Gong, Huadong Zhou, Fang Li , et al. · 2025

Genetical and Morphological Identification of Prosthogonimus pellucidus (Digenea, Prosthogonimidae) in Grus japonensis Open

Yu Cao, Ye Li, Zhong-Yan Gao, Xianguang Zhang, Botao Jiang , et al. · 2024

Species of the family Prosthogonimidae are considered the most pathogenic trematodes of poultry and wild birds worldwide, causing heavy economic losses in many countries. Prosthogonimosis was a common parasitic disease of Grus japonensis (…

Genome-wide analysis reveals genomic diversity and signatures of selection in Qinchuan beef cattle Open

Hengwei Yu, Ke Zhang, Gong Cheng, Chugang Mei, Hongbao Wang , et al. · 2024

Study on the Regional Applicability of Solar-Powered Zero-Carbon Refrigerated Display Cabinet Across China Open

Bo Zhang, Ming Bao, Lina Gong, Huadong Zhou, Fang Li , et al. · 2024

Mechanism of positive electret inhibition of Staphylococcus aureus biofilms Open

Hongbao Wang, Hejuan Liang, Xin Dong Guo, Jiajie Xu, Jian Jiang , et al. · 2023

Bacterial biofilm is an important factor in bacterial drug resistance. Recently, it has been proved that electret films can inhibit the bacterial biofilm, while its mechanism of action on biofilms is under further investigation. In this wo…

Symmetric inheritance of parental histones contributes to safeguarding the fate of mouse embryonic stem cells during differentiation Open

Qing Wen, Jiaqi Zhou, Congcong Tian, Xinran Li, Guibing Song , et al. · 2023

Electret prevents the formation of bacterial biofilm Open

Zhipeng Sun, Hongbao Wang, Xin Dong Guo, Jiajie Xu, Hejuan Liang , et al. · 2023

Bacterial biofilm formation is an important factor in bacterial resistance. The commonly used methods to inhibit bacterial biofilms are synthetic drugs such as antimicrobial peptides, but physical methods are often safe, non‐toxic and simp…

DYRK1A: A promising protein kinase target for cardiomyocyte cycling and cardiac repair through epigenetic modifications Open

Yihua Bei, Hongbao Wang, Junjie Xiao · 2022

Biological Control Efficacy of Bacillus Licheniformis Hg03 Against Soft Rot Disease of Postharvest Peach Open

Yunpeng Wang, Xiaoli Wang, Jingfeng Zhu, Huan Wei, Zhipeng Ding , et al. · 2022

Downregulation of circ-ZNF609 Promotes Heart Repair by Modulating RNA N 6 -Methyladenosine-Modified Yap Expression Open

Lijun Wang, Pujiao Yu, Jiaqi Wang, Gui-e Xu, Tianhui Wang , et al. · 2022

Circular RNAs take crucial roles in several pathophysiological processes. The regulatory role and its underlying mechanisms of circ-ZNF609 in the heart remains largely unknown. Here, we report that circ-ZNF609 is upregulated during myocard…

Identification of genetic variants the CCKAR gene and based on body measurement and carcass quality characteristics in Qinchuan beef cattle (Bos taurus) Open

Nurgulsim Kaster, Sayed Haidar Abbas Raza, Rajwali Khan, Mujahid Ali Shah, Ali Raza Jahejo , et al. · 2021

Background: This study aimed to explore genetic polymorphisms of the CCKAR gene and their relationship with the growth and development of Qinchuan cattle which could be used as molecular markers for the improvement of the breeding of Qinch…

Function and Transcriptional Regulation of Bovine TORC2 Gene in Adipocytes: Roles of C/EBPγ, XBP1, INSM1 and ZNF263 Open

Rajwali Khan, Sayed Haidar Abbas Raza, Zainaguli Junjvlieke, Xiaoyu Wang, Matthew Garcia , et al. · 2019

The TORC2 gene is a member of the transducer of the regulated cyclic adenosine monophosphate (cAMP) response element binding protein gene family, which plays a key role in metabolism and adipogenesis. In the present study, we confirmed the…

The MEDEA FAR-EAST Study: Conceptual framework, methods and first findings of a multicenter cross-sectional observational study Open

Sophia Hoschar, Jiangqi Pan, Zhen Wang, Xiaoyan Fang, Xiane Tang , et al. · 2019

Overexpression of the Rybp Gene Inhibits Differentiation of Bovine Myoblasts into Myotubes Open

Xiao‐Tong Su, Yanfang Zhao, Yaning Wang, Le Zhang, Zan Lin-sen , et al. · 2018

RING1 and YY1 binding protein (Rybp) genes inhibit myogenesis in mice, but there are no reports on the effects of these genes in cattle. The aim of this study is to investigate the roles of the Rybp gene on bovine skeletal muscle developme…

Genetic Variants in STAT3 Promoter Regions and Their Application in Molecular Breeding for Body Size Traits in Qinchuan Cattle Open

Sen Wu, Yaning Wang, Yue Ning, Hongfang Guo, Xiaoyu Wang , et al. · 2018

Signal transducer and activator of transcription 3 (STAT3) plays a critical role in leptin-mediated regulation of energy metabolism. This study investigated genetic variation in STAT3 promoter regions and verified their contribution to bov…

Transcriptional Regulation by CpG Sites Methylation in the Core Promoter Region of the Bovine SIX1 Gene: Roles of Histone H4 and E2F2 Open

Dawei Wei, Anning Li, Chunping Zhao, Hongbao Wang, Chugang Mei , et al. · 2018

DNA methylation is a major epigenetic modification of the genome and has an essential role in muscle development. The SIX1 gene is thought to play a principal role in mediating skeletal muscle development. In the present study, we determin…

Transcriptome analysis of mRNA and microRNAs in intramuscular fat tissues of castrated and intact male Chinese Qinchuan cattle Open

Yingying Zhang, Hongbao Wang, Yaning Wang, Hongcheng Wang, Song Zhang , et al. · 2017

Intramuscular fat (IMF) is known to enhance beef palatability and can be markedly increased by castration. However, there is little understanding of the molecular mechanism underlying the IMF deposition after castration of beef cattle. We …

Cardiac cell proliferation is not necessary for exercise‐induced cardiac growth but required for its protection against ischaemia/reperfusion injury Open

Yihua Bei, Siyi Fu, Xiangming Chen, Mei Chen, Qiulian Zhou , et al. · 2017

The adult heart retains a limited ability to regenerate in response to injury. Although exercise can reduce cardiac ischaemia/reperfusion (I/R) injury, the relative contribution of cardiac cell proliferation including newly formed cardiomy…

Bioinformatics Analysis Reveals MicroRNAs Regulating Biological Pathways in Exercise-Induced Cardiac Physiological Hypertrophy Open

Jiahong Xu, Yang Liu, Yuan Xie, Cuimei Zhao, Hongbao Wang · 2017

Exercise-induced physiological cardiac hypertrophy is generally considered to be a type of adaptive change after exercise training and is beneficial for cardiovascular diseases. This study aims at investigating exercise-regulated microRNAs…

Ectopical expression of FABP4 gene can induce bovine muscle-derived stem cells adipogenesis Open

Le Zhang, Yanfang Zhao, Yue Ning, Hongbao Wang, Linsen Zan · 2016

Fatty acid binding protein 4 (FABP4) plays a key role in Fatty acid catabolism in mammals. Findings from our previous studies have indicated that FABP4 neither affect the differentiation of bovine preadipocytes nor does it change the expre…

Telocytes in exercise‐induced cardiac growth Open

Junjie Xiao, Ping Chen, Yi Qu, Pujiao Yu, Jianhua Yao , et al. · 2016

Exercise can induce physiological cardiac growth, which is featured by enlarged cardiomyocyte cell size and formation of new cardiomyocytes. Telocytes ( TC s) are a recently identified distinct interstitial cell type, existing in many tiss…

miR-19b attenuates H2O2-induced apoptosis in rat H9C2 cardiomyocytesviatargeting PTEN Open

Jiahong Xu, Yu Tang, Yihua Bei, Shengguang Ding, Lin Che , et al. · 2016

Myocardial ischemia-reperfusion (I-R) injury lacks effective treatments. The miR-17-92 cluster plays important roles in regulating proliferation, apoptosis, cell cycle and other pivotal processes. However, their roles in myocardial I-R inj…

Whole-genome sequencing of the endangered bovine species Gayal (Bos frontalis) provides new insights into its genetic features Open

Chugang Mei, Hongcheng Wang, Wenjuan Zhu, Hongbao Wang, Gong Cheng , et al. · 2016

Gayal ( Bos frontalis ) is a semi-wild and endangered bovine species that differs from domestic cattle ( Bos taurus and Bos indicus ) and its genetic background remains unclear. Here, we performed whole-genome sequencing of one Gayal for t…

Circulating miR-21, miR-378, and miR-940 increase in response to an acute exhaustive exercise in chronic heart failure patients Open

Tianzhao Xu, Qiulian Zhou, Lin Che, Saumya Das, Lemin Wang , et al. · 2016

Congestive heart failure (CHF) is a major cause of hospitalizations, morbidity, and mortality in Western societies. In addition to optimal medical and device therapy, exercise training is an important adjunct treatment option for CHF patie…

Deregulated Cardiac Specific MicroRNAs in Postnatal Heart Growth Open

Pujiao Yu, Hongbao Wang, Yuan Xie, Jinzhe Zhou, Jianhua Yao , et al. · 2016

The heart is recognized as an organ that is terminally differentiated by adulthood. However, during the process of human development, the heart is the first organ with function in the embryo and grows rapidly during the postnatal period. M…

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