Hongbin Zhu
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View article: Correction: Impact of comorbid depression on quality of life and disease progression in chronic obstructive pulmonary disease: a correlational analysis
Correction: Impact of comorbid depression on quality of life and disease progression in chronic obstructive pulmonary disease: a correlational analysis Open
[This corrects the article DOI: 10.3389/fpsyt.2025.1667902.].
View article: Impact of comorbid depression on quality of life and disease progression in chronic obstructive pulmonary disease: a correlational analysis
Impact of comorbid depression on quality of life and disease progression in chronic obstructive pulmonary disease: a correlational analysis Open
Introduction Depression is a prevalent comorbidity in patients with Chronic Obstructive Pulmonary Disease (COPD), particularly during acute exacerbations (AECOPD), significantly impacting prognosis and quality of life. This study aimed to …
View article: A novel prognostic risk score associated with resistance to docetaxel chemotherapy for predicting biochemical recurrence-free survival in patients with prostate cancer
A novel prognostic risk score associated with resistance to docetaxel chemotherapy for predicting biochemical recurrence-free survival in patients with prostate cancer Open
View article: GPM6B inhibits tumor progression by targeting HPGD in lung adenocarcinoma
GPM6B inhibits tumor progression by targeting HPGD in lung adenocarcinoma Open
Lung adenocarcinoma (LUAD) is the most prevalent form of lung cancer and the predominant cause of cancer-associated mortality. Given the low survival rate of patients with LUAD, there is a need to identify new therapeutic targets. Glycopro…
View article: Development and validation of a predictive model for acute exacerbation in chronic obstructive pulmonary disease patients with comorbid insomnia
Development and validation of a predictive model for acute exacerbation in chronic obstructive pulmonary disease patients with comorbid insomnia Open
Aim To develop and validate a risk prediction model for estimating the likelihood of insomnia in patients with acute exacerbations of chronic obstructive pulmonary disease (AECOPD). Methods This prospective study enrolled 253 patients with…
View article: Investigating the risk factors for the coexistence of insomnia and its exacerbation in AECOPD
Investigating the risk factors for the coexistence of insomnia and its exacerbation in AECOPD Open
Insomnia coexisting with AECOPD is prevalent, with the patient's gender, educational level, smoking history, severity of clinical symptoms, and the type of treatment influencing their sleep status.
View article: CTSG is a prognostic marker involved in immune infiltration and inhibits tumor progression though the MAPK signaling pathway in non-small cell lung cancer
CTSG is a prognostic marker involved in immune infiltration and inhibits tumor progression though the MAPK signaling pathway in non-small cell lung cancer Open
CTSG inhibits NSCLC development by suppressing the MAPK signaling pathway and is also associated with tumor immunity.
View article: Characteristics of strong earthquake preparation in main-seismic type and multi-seismic type earthquake segments in the North China tectonic region
Characteristics of strong earthquake preparation in main-seismic type and multi-seismic type earthquake segments in the North China tectonic region Open
The North China Tectonic Zone (NCTZ) is the most seismically active area in eastern China, where a large number of strong earthquakes, especially M8 or so, had occurred. In order to study the risk of future strong earthquakes in the NCTZ, …
View article: A single-center, retrospective study-spring-evaluating the efficacy and safety of recombinant human vascular endothelial inhibitor combined with anti-PD-1 in elderly patients aged 80 and above with NSCLC
A single-center, retrospective study-spring-evaluating the efficacy and safety of recombinant human vascular endothelial inhibitor combined with anti-PD-1 in elderly patients aged 80 and above with NSCLC Open
Aim To investigate the efficacy and safety of combining Recombinant Human Endostatin Injection (marketed as Endo) with anti-PD-1 in elderly patients aged 80 and above with non-small cell lung cancer (NSCLC). Methods Retrospective analysis …
View article: Loading/Unloading Effect Analysis of Strong Earthquakes in Northern North China
Loading/Unloading Effect Analysis of Strong Earthquakes in Northern North China Open
Based on the numerical simulation method and Coulomb stress change, we calculate the stress change of strong earthquakes of Ms≥6.5 in northern North China, and discuss the loading/unloading effect of strong shock on the future event. The r…
View article: HIV associated factors among men who have sex with men in Maanshan, China: a cross-sectional study
HIV associated factors among men who have sex with men in Maanshan, China: a cross-sectional study Open
View article: HIV associated factors among men who have sex with men in Maanshan, China: a cross-sectional study
HIV associated factors among men who have sex with men in Maanshan, China: a cross-sectional study Open
Background: This study conducted a survey of men who have sex with men (MSM) in Maanshan City of Anhui Province to assess the risk behaviors related to human immunodeficiency virus (HIV) infection.. Methods: A cross-sectional survey was co…
View article: Retinoic Acid-Induced 2 (RAI2) Is a Novel Antagonist of Wnt/β-Catenin Signaling Pathway and Potential Biomarker of Chemosensitivity in Colorectal Cancer
Retinoic Acid-Induced 2 (RAI2) Is a Novel Antagonist of Wnt/β-Catenin Signaling Pathway and Potential Biomarker of Chemosensitivity in Colorectal Cancer Open
Objective Aberrant activation of Wnt/β-catenin signaling contributes to the maintenance of cancer stem cells and chemoresistance in colorectal cancer (CRC). Retinoic acid-induced 2 (RAI2) was proved to be a tumor suppressor in CRC in our p…
View article: Chronic Stress Activates PlexinA1/VEGFR2-JAK2-STAT3 in Vascular Endothelial Cells to Promote Angiogenesis
Chronic Stress Activates PlexinA1/VEGFR2-JAK2-STAT3 in Vascular Endothelial Cells to Promote Angiogenesis Open
It is known that chronic stress modulates multiple processes in a complex microenvironment, such as angiogenesis and immune function. However, the role of chronic stress inducing tumor angiogenesis and how it contributes to tumor progressi…
View article: Investigation and Analysis of Iron-Deficiency Anemia Complicated by Splenomegaly
Investigation and Analysis of Iron-Deficiency Anemia Complicated by Splenomegaly Open
IDA is correlated with the incidence of splenomegaly, and the incidence of splenomegaly significantly increases as the severity of IDA increases. This is considered to be caused by extramedullary hematopoiesis.
View article: Security assessment of power data link based on dynamic weight change
Security assessment of power data link based on dynamic weight change Open
The Data link security assessment is to ensure the security of data transmission, data storage and data usage in the link. It is an important standard to reflect the safety of data link in time and accurately. We proposed a data link secur…
View article: Semi-Supervised Fuzzy C-Means Clustering Optimized by Simulated Annealing and Genetic Algorithm for Fault Diagnosis of Bearings
Semi-Supervised Fuzzy C-Means Clustering Optimized by Simulated Annealing and Genetic Algorithm for Fault Diagnosis of Bearings Open
As a popular clustering algorithms, fuzzy c-means (FCM) algorithm has been used in various fields, including fault diagnosis, machine learning. To overcome the sensitivity to outliers problem and the local minimum problem of the fuzzy c-me…
View article: Efficacy of Autologous Bone Marrow Mononuclear Cell Transplantation Therapy for Type 2 Diabetes Mellitus: An Updated Meta-Analysis
Efficacy of Autologous Bone Marrow Mononuclear Cell Transplantation Therapy for Type 2 Diabetes Mellitus: An Updated Meta-Analysis Open
Autologous stem cell therapy showed a beneficial effect on T2DM.
View article: Association between interleukin 37 (rs3811047) polymorphism and multiple autoimmune diseases in a Chinese population
Association between interleukin 37 (rs3811047) polymorphism and multiple autoimmune diseases in a Chinese population Open
The IL- 37 (rs3811047) polymorphism contributes to the development of ADs in a Chinese population.
View article: Combining the Multi‐Genetic Algorithm and Support Vector Machine for Fault Diagnosis of Bearings
Combining the Multi‐Genetic Algorithm and Support Vector Machine for Fault Diagnosis of Bearings Open
Overstudy or understudy phenomena can sometimes occur due to the strong dependence of support vector machine (SVM) algorithms on particular parameters and the lack of systems theory relating to parameter selection. In this paper, a paramet…
View article: Abnormal Detection of Electric Management System based on Spatial-temporal User Profile
Abnormal Detection of Electric Management System based on Spatial-temporal User Profile Open
Abnormal detection of user behavior is essential for Electric Management Information System to ensure its stable operations. In this paper, we propose a user profile based abnormal behavior detection algorithm based on spatial-temporal dat…
View article: User Behavior Auditing in Electric Management Information System based on Graph Clustering
User Behavior Auditing in Electric Management Information System based on Graph Clustering Open
In this paper, we propose a user behavior auditing algorithm based on graph clustering. First, we record the user operations in the electric management information system (MIS) and convert the log data into graph representation which inclu…
View article: Characterization and interstrain transfer of prophage pp3 of Pseudomonas aeruginosa
Characterization and interstrain transfer of prophage pp3 of Pseudomonas aeruginosa Open
Prophages are major contributors to horizontal gene transfer and drive the evolution and diversification of bacteria. Here, we describe the characterization of a prophage element designated pp3 in the clinical Pseudomonas aeruginosa isolat…
View article: Anti-obesity Effect of Capsaicin in Mice Fed with High-Fat Diet Is Associated with an Increase in Population of the Gut Bacterium Akkermansia muciniphila
Anti-obesity Effect of Capsaicin in Mice Fed with High-Fat Diet Is Associated with an Increase in Population of the Gut Bacterium Akkermansia muciniphila Open
Capsaicin (CAP) reduces body weight mainly through activation of transient receptor potential vanilloid 1 (TRPV1) cation channel. However, recent evidence indicates that the gut microbiota influences many physiological processes in host an…
View article: Self-mixing birefringent dual-frequency laser Doppler velocimeter
Self-mixing birefringent dual-frequency laser Doppler velocimeter Open
A self-mixing birefringent dual-frequency laser Doppler velocimeter (SBD-LDV) for high-resolution velocity measurements is presented in this paper. The velocity information of the object can be accurately extracted from the self-mixing Dop…
View article: Loss of PRRX1 induces epithelial-mesenchymal transition and cancer stem cell-like properties in A549 cells.
Loss of PRRX1 induces epithelial-mesenchymal transition and cancer stem cell-like properties in A549 cells. Open
Epithelial-mesenchymal transition (EMT) plays crucial role in tumor metastasis and patient prognosis. Previous studies indicated that paired-related homeobox 1 (PRRX1), a newly identified EMT inducer, plays opposing roles in different tumo…
View article: The role of PRRX1 in the apoptosis of A549 cells induced by cisplatin.
The role of PRRX1 in the apoptosis of A549 cells induced by cisplatin. Open
Paired related homeobox1 (PRRX1) was a newly identified Epithelial mesenchymal transition (EMT) inducer. It was found that the decreased expression of PRRX1 in breast cancer and liver cancer could enable tumor cells to obtain tumor stem ce…
View article: Protective effect of geraniol inhibits inflammatory response, oxidative stress and apoptosis in traumatic injury of the spinal cord through modulation of NF-κB and p38 MAPK
Protective effect of geraniol inhibits inflammatory response, oxidative stress and apoptosis in traumatic injury of the spinal cord through modulation of NF-κB and p38 MAPK Open
Geraniol is a type of monoterpenoid with a rose scent and a slightly sweet flavor. It is found in the volatile oil of various plants, and has anti-inflammatory and anti-oxidant effects. The present study aimed to investigate the protective…
View article: Genomic analyses of multidrug resistant <i>Pseudomonas aeruginosa</i> PA1 resequenced by single-molecule real-time sequencing
Genomic analyses of multidrug resistant <i>Pseudomonas aeruginosa</i> PA1 resequenced by single-molecule real-time sequencing Open
As a third-generation sequencing (TGS) method, single-molecule real-time (SMRT) technology provides long read length, and it is well suited for resequencing projects and de novo assembly. In the present study, Pseudomonas aeruginosa PA1 wa…
View article: Characterization and Comparative Genomic Analyses of Pseudomonas aeruginosa Phage PaoP5: New Members Assigned to PAK_P1-like Viruses
Characterization and Comparative Genomic Analyses of Pseudomonas aeruginosa Phage PaoP5: New Members Assigned to PAK_P1-like Viruses Open