Explanipedia

Implementation Challenges of Remote Cancer Symptom Management With Electronic Patient‑Reported Outcomes in China’s Primary Health Care Settings: Qualitative Study Open

Min Li, Jingyu Zhang, Jundi Zheng, Changjin Wu, Zezhong Shao , et al. · 2025

Background Electronic patient-reported outcomes (ePROs)–based cancer symptom management presents an opportunity to improve patient outcomes by optimizing symptom detection and prompting clinician interventions in tertiary hospitals. Howeve…

Pain and Its Treatment Among Outpatients with Malignant Tumors in China Open

Peiyang Mao, Xin Tian, Yinxia Zhan, Feng Gao, Xiangyu Tan , et al. · 2025

Pain management is challenging for patients aged ≥60 years. Therefore, tailored interventions are needed to enhance care quality.

Sex-related differences in postoperative patient-reported outcomes among lung cancer patients: a multicenter cohort study Open

Jia Liao, Xiaoqun Hu, Xing Wei, Wei Dai, Hongfan Yu , et al. · 2025

Efficacy of digital therapeutics for perioperative management in patients with lung cancer: a randomized controlled trial Open

Jinming Xu, Heng Ni, Hanyu Zhan, Hongfan Yu, Zhongjie Lu , et al. · 2025

ChiCTR2200064723.

Long‐Term Function Recovery Following Upper Versus Lower Lobectomy for Lung Cancer: A Multicenter Longitudinal Cohort Study Open

Xing Wei, Hongfan Yu, Bellinda L. King‐Kallimanis, Yangjun Liu, Lin Huang , et al. · 2024

Background The effects of lobectomy at various lung sites on postoperative function and recovery vary. This study aimed at assessing the long‐term impact of upper versus lower lobectomy on patients' postoperative daily function by analyzin…

Perceptions of clinicians and research ethics boards regarding ethical issues in investigator-initiated trials: a multicenter qualitative study in China Open

Jing Li, Hongfan Yu, Xing Wei, Lei Cheng, Jingyu Zhang , et al. · 2024

Purpose This multicenter qualitative study aimed to explore the perceptions of clinicians and research ethics boards (REBs) regarding ethical issues in Investigator Initiated Trials (IITs). Methods Between February and April 2024, semi-str…

Establishment of electronic patient-reported-outcome symptom monitoring- alerting-intervening (ePRO-SMAI) pathway with metastatic cancer: a protocol for a mixed-design longitudinal cohort study Open

Li Tang, Hongfan Yu, Da Miao, Jingyu Zhang, Lei Cheng , et al. · 2024

Introduction: Patient-reported outcome (PRO)-based symptom assessment and evaluation of oncological treatment recovery are becoming increasingly important in clinical practice. Although electronic PRO systems are promising, their proactive…

Patient-reported walking difficulty predicting the post-discharge overall function in patients with lung cancer undergoing minimally invasive surgery Open

Xin Tian, Peiyang Mao, Lei Cheng, Hongfan Yu, Wei Dai , et al. · 2024

Background Postoperative mobility of patients with lung cancer is crucial for their physical rehabilitation. This study aimed to identify severe walking difficulty and establish a threshold for predicting the functional recovery of patient…

Joint use of population pharmacokinetics and machine learning for prediction of valproic acid plasma concentration in elderly epileptic patients Open

Pan Ma, Shenglan Shang, Yifan Huang, Ruixiang Liu, Hongfan Yu , et al. · 2024

Our model was specifically tailored for elderly epileptic patients, providing an efficient and cost-effective approach to predict VPA plasma concentration. The model combined classical PPK with machine learning, and underwent optimization …

Electronic patient-reported outcome-based surveillance system to evaluate safety and efficacy of preoperative immunochemotherapy with or without short-term chemoradiation in patients with esophageal squamous cell carcinoma (ePRO-PICCRT): protocol for a prospective, single-arm, phase II study Open

Shujie Huang, Hongfan Yu, Zijie Li, Yong Tang, Li-Ling Luo , et al. · 2024

This study is registered at Clinicaltrials.gov (NCT05596890).

Electronic symptom monitoring after lung cancer surgery: establishing a core set of patient-reported outcomes for surgical oncology care in a longitudinal cohort study Open

Hongfan Yu, Lei Cheng, Xing Wei, Yaqin Wang, Wei Xu , et al. · 2024

Background: Electronic symptom monitoring via patient-reported outcomes in surgical oncology is limited owing to lengthy instruments and non-specific items in common patient-reported outcome instruments. To establish electronic symptom mon…

Comparison of early patient-reported outcomes between uniportal thoracoscopic segmentectomy and wedge resection for peripheral small-sized non-small-cell lung cancer Open

Yingzhi Zhao, Wenwu Liu, Xin Gao, Kaixin Zhang, Wei Dai , et al. · 2024

Background Analysis of patient-reported outcomes (PROs) offers valuable insights into distinguishing the effects of closely related medical procedures from the patient’s perspective. In this study we compared symptom burden in patients und…

Electronic Patient-Reported Outcome–Based Symptom Management Versus Usual Care After Lung Cancer Surgery: Long-Term Results of a Multicenter, Randomized, Controlled Trial Open

Wei Dai, Yaqin Wang, Jia Liao, Xing Wei, Zhen Dai , et al. · 2024

Clinical trials frequently include multiple end points that mature at different times. The initial report, typically based on the primary end point, may be published when key planned co-primary or secondary analyses are not yet available. …

Multidisciplinary management and surgical resection of a rare posterior mediastinal haemangioma Open

Kaixin Zhang, Wei Dai, Hongfan Yu, Qiuling Shi, Shaohua Xie , et al. · 2024

Mediastinal haemangiomas pose diagnostic and therapeutic challenges owing to their rarity and complex anatomy. A 36-year-old man, with a history of smoking and drinking, presented with a posterior mediastinal mass with back pain. Initial i…

Extended radical resection and chest wall reconstruction for a pulmonary sarcomatoid carcinoma: a case report Open

Yingzhi Zhao, Shaohua Xie, Haoqian Zheng, Kaixin Zhang, Xin Gao , et al. · 2024

Background Pulmonary sarcomatoid carcinoma (PSC) is a rare and highly malignant type of non-small cell lung cancer (NSCLC), for which the treatment of choice is surgery. For peripheral PSC growing outward and invading the chest wall, a com…

Comparison of early patient-reported outcomes between uniportal thoracoscopic segmentectomy and wedge resection for peripheral small-sized non-small-cell lung cancer Open

Yingzhi ZHAO, Wenhao Liu, Xin GAO, Kaixin Zhang, Wei Dai , et al. · 2023

Background: Analysis of patient-reported outcomes (PROs) offers valuable insights into distinguishing the effects of closely related medical procedures from the patient’s perspective. In this study we compared symptom burden in patients un…

Remote research burden of follow-up in longitudinal patient-reported outcomes (PROs) data collection: An exploratory sequential mixed-methods study (Preprint) Open

Ruoyan Gong, Lijun Zhang, Xueyao Su, Lei Cheng, Hongfan Yu , et al. · 2023

BACKGROUND Longitudinal patient-reported outcomes studies require questionnaire assessments to be administered remotely multiple times, burdening research staff. OBJECTIVE To define and quantify the burden that researcher may experience…

Using Clinician-Patient WeChat Group Communication Data to Identify Symptom Burdens in Patients With Uterine Fibroids Under Focused Ultrasound Ablation Surgery Treatment: Qualitative Study Open

Jiayuan Zhang, Wei Xu, Lei Cheng, Yang Pu, Yubo Zhang , et al. · 2023

Background Unlike research project–based health data collection (questionnaires and interviews), social media platforms allow patients to freely discuss their health status and obtain peer support. Previous literature has pointed out that …

Using Clinician-Patient WeChat Group Communication Data to Identify Symptom Burdens in Patients With Uterine Fibroids Under Focused Ultrasound Ablation Surgery Treatment: Qualitative Study (Preprint) Open

Jiayuan Zhang, Wei Xu, Lei Cheng, Yang Pu, Yubo Zhang , et al. · 2022

BACKGROUND Unlike research project–based health data collection (questionnaires and interviews), social media platforms allow patients to freely discuss their health status and obtain peer support. Previous literature has pointed out that…

Shortness of breath on day 1 after surgery alerting the presence of postoperative pulmonary complications in patients with lung cancer Open

Qingsong Yu, Hongfan Yu, Wei Xu, Yang Pu, Yuxian Nie , et al. · 2022

Background: Patient-reported outcome (PRO)-based symptom assessment with a threshold can facilitate the early alert of adverse events. The purpose of this study was to determine whether shortness of breath (SOB) on postoperative day 1 (POD…

Profiling symptom burden and its influencing factors at discharge for patients undergoing lung cancer surgery: a cross-sectional analysis Open

Jia Liao, Yaqin Wang, Wei Dai, Xing Wei, Hongfan Yu , et al. · 2022

Background Following lung cancer surgery, patients often experience severe symptoms which are not properly assessed at discharge. The aim of this study was to identify the clinical presentation at discharge and the influencing factors of p…

Protocol of an iterative qualitative study to develop a molecular testing decision aid for shared decision-making in patients with lung cancer after surgery Open

Xing Wei, Yangjun Liu, Hongfan Yu, Wei Dai, Ding Yang , et al. · 2022

Introduction Although molecular testing is crucial for many patients with lung cancer, the decision to carry out molecular testing is not easy to make in actual clinical scenarios. Using a specific decision aid (DA) to conduct shared decis…

Correction to: Establishment of Minimal Clinically Important Improvement for Patient-Reported Symptoms to Define Recovery After Video-Assisted Thoracoscopic Surgery Open

Wei Xu, Wei Dai, Zhen Gao, Xin Shelley Wang, Li Tang , et al. · 2022

Shortness of Breath on Day 1 After Surgery Alerting the Presence of Early Respiratory Complications After Surgery in Lung Cancer Patients Open

Qingsong Yu, Hongfan Yu, Wei Xu, Yang Pu, Yuxian Nie , et al. · 2022

Qingsong Yu,1 Hongfan Yu,1 Wei Xu,1 Yang Pu,1 Yuxian Nie,2 Wei Dai,3 Xing Wei,3 Xin Shelley Wang,4 Charles S Cleeland,4 Qiang Li,3 Qiuling Shi1,2,5 1School of Public Health and Management, Chongqing Medical University, Chongqing, People’s …

Implementation of an Evidence-Based Electronic Patient-Reported-Outcome Symptom Monitoring-Alerting-Responding System (ePRO-SMARS) for Thoracic Surgery: A Longitudinal Cohort Study Open

Cheng Deng, Hongfan Yu, Yinghong Wu, Cheng Zeng, Xu Wang , et al. · 2022

Data Quality of Longitudinally Collected Patient-Reported Outcomes After Thoracic Surgery: Comparison of Paper- and Web-Based Assessments Open

Hongfan Yu, Qingsong Yu, Yuxian Nie, Wei Xu, Yang Pu , et al. · 2021

Background High-frequency patient-reported outcome (PRO) assessments are used to measure patients' symptoms after surgery for surgical research; however, the quality of those longitudinal PRO data has seldom been discussed. Objective The a…

Correction to: Patient-Reported Outcomes of Video-Assisted Thoracoscopic Surgery Versus Thoracotomy for Locally Advanced Lung Cancer: A Longitudinal Cohort Study Open

Xing Wei, Hongfan Yu, Wei Dai, Yunfei Mu, Yaqin Wang , et al. · 2021

Middle-aged and elderly users’ continuous usage intention of health maintenance-oriented WeChat official accounts: empirical study based on a hybrid model in China Open

Xu Lin, Pengfei Li, Xiaorong Hou, Hongfan Yu, Tingting Tang , et al. · 2021

Profiling Patient-Reported Symptom Recovery from Esophagectomy for Patients with Esophageal Squamous Cell Carcinoma: A Real World Longitudinal Study Open

Xi Luo, Qin Xie, Qiuling Shi, Yan Miao, Qingsong Yu , et al. · 2021

Purpose: Esophageal squamous cell carcinoma (ESCC) patients have severe symptom burden after esophagectomy; however, longitudinal studies of symptom recovery after surgery are scarce. This study used longitudinal patient-reported outcome (…

Discrepancy in perception of symptoms among patients and medical staff after lung cancer surgery Open

Xing Wei, Hongfan Yu, Wei Dai, Wei Xu, Qingsong Yu , et al. · 2021

Context: Patients undergoing surgery for lung cancer experience a variety of symptoms such as pain and coughing, which interfere patients’ daily function after surgery. However, there may be some differences between the perception of sympt…

Hongfan Yu YOU? Author Swipe